Hims vs PlexusDx: Which GLP-1 Program Is Better? (2026)
A detailed side-by-side comparison of Hims and PlexusDx to help you choose the right GLP-1 weight loss program based on pricing, medications, medical support, and more.
Quick Verdict
We recommend PlexusDx
Between these two providers, PlexusDx is our pick for most users. It offers a higher overall rating (7.6 vs 6.7), availability in all 50 states. That said, Hims may be the better fit if you are looking for people who want brand-name glp-1s, including oral options, through a mainstream telehealth brand.
PlexusDx scores 7.6/10 in our evaluation at $149/month, while Hims scores 6.7/10 at $149/month. Both programs include a licensed physician consultation and ship medication directly to your door. PlexusDx also offers oral GLP-1 options for patients who prefer pills over injections. Our rating considers five factors: safety and medical oversight (30%), pricing transparency (25%), cost value (20%), clinical support quality (15%), and onboarding speed (10%). We earn affiliate commissions from some providers, disclosed on this page; no provider can pay to fake safety, licensing, or hide the downsides. Prices verified April 2026.
Side-by-Side Comparison
| Feature | Hims | PlexusDx |
|---|---|---|
| Monthly Price | $149 | $149 |
| Rating | 6.7 / 10 | 7.6 / 10 |
| Medication Type | Brand-Name Only | Compounded Only |
| Insurance Accepted | No | No |
| States Available | 45 states | All 50 states |
| Consultation Fee | $0 | Included |
| Shipping | Free Shipping | Free Shipping |
| Cancel Anytime | Yes | Yes |
| Medical Support | Licensed healthcare providers via online consultation | US-licensed clinicians (LionMD network) via async intake, monthly check-ins and provider-reviewed refills; five states require a scheduled video consultation |
Prices reflect starting rates without insurance. Actual costs may vary by plan and medication. Last updated April 2026.
Hims: Detailed Look
Hims
Mainstream telehealth offering brand-name GLP-1s, including oral options
Pros
- Broad FDA-approved GLP-1 menu — Wegovy, Zepbound, Ozempic, plus newly approved oral Foundayo
- Oral GLP-1 options for needle-averse patients
- Large, established mainstream brand with a polished app and free shipping
- First month membership discounted to $39
Cons
- $149/mo membership adds on top of brand medication priced at Novo's own self-pay rate — realistic all-in $298–$448/mo
- No longer lists compounded semaglutide for new patients (March 2026 shift to FDA-approved products)
- Cash-pay only — does not bill insurance
- Trustpilot 2.9/5 on hims.com; subscription and billing complaints dominate recent reviews
- FDA warning letter (Sep 2025) over compounded-semaglutide claims; FTC + CA/UT lawsuit filed Jul 2026 (allegations, disputed by the company)
people who want brand-name GLP-1s, including oral options, through a mainstream telehealth brand
PlexusDx: Detailed Look
PlexusDx
All-inclusive compounded GLP-1 with flat pricing at every dose and an optional genetic test
Pros
- All-inclusive pricing with no membership fee: consult, prescription, medication, supplies and shipping in one monthly charge
- Flat price at every dose level, so the monthly cost does not rise as your dose is titrated up
- LegitScript certified (September 18, 2026), with its 503A compounding pharmacies named on the site
- Available in all 50 states, with injection, oral and low-dose microdose options
Cons
- Compounded medications are not FDA-approved
- Month-to-month pricing ($189 semaglutide, $289 tirzepatide) is well above the cheapest programs; the lower rates need a 3- or 6-month commitment
- No published refund policy, and the genetic test is an extra $99 that does not decide which medication you get
Users who want one all-inclusive price that never changes with dose, and are curious about an optional genetic report
Which Should You Choose?
The right choice depends on your specific needs and priorities. Here is a quick decision framework:
Go with Hims at $149/month. Medication 'from' prices ($149 Wegovy pill/Foundayo, $199 Wegovy pen, $299 Zepbound) plus a separate $149/mo membership ($39 first month), so realistic all-in cost is $298–$448/mo. Hims stopped advertising and listing compounded GLP-1s for new patients in March 2026 and moved to FDA-approved products (Novo Nordisk dismissed its suit the same day, without prejudice). Cash-pay only..
PlexusDx has the edge with a 7.6 rating.
Choose Hims which exclusively prescribes brand-name medications.
PlexusDx focuses on compounded medications at a lower price point.
Compare their support: Hims offers licensed healthcare providers via online consultation, while PlexusDx provides us-licensed clinicians (lionmd network) via async intake, monthly check-ins and provider-reviewed refills; five states require a scheduled video consultation.
Frequently Asked Questions
Is Hims better than PlexusDx?
Hims has a 6.7 rating while PlexusDx has a 7.6 rating. The better choice depends on your priorities — Hims is best for people who want brand-name glp-1s, including oral options, through a mainstream telehealth brand, while PlexusDx is best for users who want one all-inclusive price that never changes with dose, and are curious about an optional genetic report.
How much does Hims cost compared to PlexusDx?
Hims starts at $149/month (medication 'from' prices ($149 wegovy pill/foundayo, $199 wegovy pen, $299 zepbound) plus a separate $149/mo membership ($39 first month), so realistic all-in cost is $298–$448/mo. hims stopped advertising and listing compounded glp-1s for new patients in march 2026 and moved to fda-approved products (novo nordisk dismissed its suit the same day, without prejudice). cash-pay only.), while PlexusDx starts at $149/month (compounded semaglutide injections $189/mo month-to-month, $169/mo on the 3-month plan and $149/mo on the 6-month plan; compounded tirzepatide injections $289 / $269 / $249. oral semaglutide runs $289 / $269 / $249 and oral tirzepatide $349 / $299 / $279; a low-dose microdose glp-1 program is $129/mo. each price is all-inclusive (provider consult, prescription, medication, supplies and shipping), stays the same at every dose level, and carries no membership fee; nothing is charged until a provider approves the prescription. the site does not say whether the 3- and 6-month tiers are billed up front. an optional glp-1 & peptide pathways genetic test is offered for $99 (list $298) after the first program order. verified october 3, 2026.).
Do Hims and PlexusDx accept insurance?
Hims does not accept insurance. PlexusDx does not accept insurance.
Which GLP-1 medications does Hims offer vs PlexusDx?
Hims offers Wegovy (injectable), Wegovy (oral), Zepbound, Ozempic, Foundayo (oral orforglipron). PlexusDx offers Compounded Semaglutide, Compounded Semaglutide (oral), Compounded Tirzepatide, Compounded Tirzepatide (oral), Microdose GLP-1.
Can I cancel Hims or PlexusDx at any time?
Hims allows cancel anytime. PlexusDx also allows cancel anytime.
Are Hims and PlexusDx available in my state?
Hims is available in 45 states. PlexusDx is available in all 50 states.
Not sure Hims or PlexusDx is right for you?
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