Trimi vs Yucca Health: Which GLP-1 Program Is Better? (2026)
A detailed side-by-side comparison of Trimi and Yucca Health to help you choose the right GLP-1 weight loss program based on pricing, medications, medical support, and more.
Quick Verdict
We recommend Yucca Health
Between these two providers, Yucca Health is our pick for most users. It offers a higher overall rating (9.2 vs 8.3), availability in all 50 states. That said, Trimi may be the better fit if you are looking for cash-pay users who want the cheapest tirzepatide from a us-licensed program.
Yucca Health scores 9.2/10 in our independent evaluation at $146/month, while Trimi scores 8.3/10 at $99/month. Both programs include a licensed physician consultation and ship medication directly to your door. Our rating considers five factors: safety and medical oversight (30%), pricing transparency (25%), cost value (20%), clinical support quality (15%), and onboarding speed (10%). This comparison was independently produced — neither provider pays for placement or higher ratings. Prices verified April 2026.
Side-by-Side Comparison
| Feature | Trimi | Yucca Health |
|---|---|---|
| Monthly Price | $99 | $146 |
| Rating | 8.3 / 10 | 9.2 / 10 |
| Medication Type | Compounded Only | Compounded Only |
| Insurance Accepted | No | No |
| States Available | 47 states | All 50 states |
| Consultation Fee | Included | Free |
| Shipping | Free Shipping | Free Shipping |
| Cancel Anytime | Yes | No |
| Medical Support | US-licensed clinicians, telehealth consults, dose adjustments | Licensed U.S. physicians (Dr. Wasef, Dr. Sakla), provider-guided care, 24hr review |
Prices reflect starting rates without insurance. Actual costs may vary by plan and medication. Last updated April 2026.
Trimi: Detailed Look
Trimi
Compounded GLP-1 from $99 with US-licensed clinicians
Pros
- Tirzepatide at $125/month — lowest tirzepatide price among verified programs
- Semaglutide at $99/month matches the market floor
- US-licensed clinicians with dose-adjustment support
- Free shipping to your door
Cons
- New program with a short independent track record
- No brand-name (Wegovy/Zepbound) pathway
Cash-pay users who want the cheapest tirzepatide from a US-licensed program
Yucca Health: Detailed Look
Yucca Health
LegitScript-certified GLP-1 provider with named physicians and BNPL financing
Pros
- LegitScript certified — pharmacy and telehealth verified
- 4.6/5 Trustpilot rating from 1,000+ verified patient reviews
- Named physicians: Dr. Michael Wasef, MD and Dr. Andrew Sakla, DO
- Buy now, pay later via Klarna, Affirm, and Afterpay
Cons
- Best pricing requires 6-month commitment
- Compounded medications only — no brand-name options
Users who want a LegitScript-certified provider with verified patient reviews and flexible financing
Which Should You Choose?
The right choice depends on your specific needs and priorities. Here is a quick decision framework:
Go with Trimi at $99/month. Semaglutide $99/mo; tirzepatide $125/mo — cheapest tirzepatide floor we track.
Yucca Health has the edge with a 9.2 rating.
Compare their support: Trimi offers us-licensed clinicians, telehealth consults, dose adjustments, while Yucca Health provides licensed u.s. physicians (dr. wasef, dr. sakla), provider-guided care, 24hr review.
Yucca Health at $146/month may offer features that justify the premium.
Frequently Asked Questions
Is Trimi better than Yucca Health?
Trimi has a 8.3 rating while Yucca Health has a 9.2 rating. The better choice depends on your priorities — Trimi is best for cash-pay users who want the cheapest tirzepatide from a us-licensed program, while Yucca Health is best for users who want a legitscript-certified provider with verified patient reviews and flexible financing.
How much does Trimi cost compared to Yucca Health?
Trimi starts at $99/month (semaglutide $99/mo; tirzepatide $125/mo — cheapest tirzepatide floor we track), while Yucca Health starts at $146/month ($146/mo semaglutide on 6-month plan, $258/mo tirzepatide. klarna/affirm/afterpay available.).
Do Trimi and Yucca Health accept insurance?
Trimi does not accept insurance. Yucca Health does not accept insurance.
Which GLP-1 medications does Trimi offer vs Yucca Health?
Trimi offers Compounded Semaglutide, Compounded Tirzepatide. Yucca Health offers Compounded Semaglutide+, Compounded Tirzepatide+.
Can I cancel Trimi or Yucca Health at any time?
Trimi allows cancel anytime. Yucca Health may have cancellation restrictions.
Are Trimi and Yucca Health available in my state?
Trimi is available in 47 states. Yucca Health is available in all 50 states.
Not sure Trimi or Yucca Health is right for you?
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