Trimi vs Yucca Health: Which GLP-1 Program Is Better? (2026)

A detailed side-by-side comparison of Trimi and Yucca Health to help you choose the right GLP-1 weight loss program based on pricing, medications, medical support, and more.

Eduard Cristea
Eduard Cristea
Dr. A. Goher, MD
Medically reviewed by Dr. A. Goher, MD
Published:

Quick Verdict

We recommend Trimi

Between these two providers, Trimi is our pick for most users. It offers a higher overall rating (9.2 vs 8.9), more affordable pricing. That said, Yucca Health may be the better fit if you are looking for users who want a legitscript-certified provider with verified patient reviews and flexible financing.

Trimi scores 9.2/10 in our evaluation at $99/month, while Yucca Health scores 8.9/10 at $125/month. Both programs include a licensed physician consultation and ship medication directly to your door. Our rating considers five factors: safety and medical oversight (30%), pricing transparency (25%), cost value (20%), clinical support quality (15%), and onboarding speed (10%). We earn affiliate commissions from some providers, disclosed on this page; no provider can pay to fake safety, licensing, or hide the downsides. Prices verified April 2026.

Side-by-Side Comparison

Monthly Price
Trimi
Yucca Health
Rating
Trimi
9.2 / 10
Yucca Health
8.9 / 10
Medication Type
Trimi
Compounded Only
Yucca Health
Compounded Only
Insurance Accepted
Trimi
No
Yucca Health
No
States Available
Trimi
47 states
Yucca Health
All 50 states
Consultation Fee
Trimi
Included
Yucca Health
Free
Shipping
Trimi
Free Shipping
Yucca Health
Free Shipping
Cancel Anytime
Trimi
Yes
Yucca Health
No
Medical Support
Trimi
US-licensed clinicians, telehealth consults, dose adjustments
Yucca Health
Licensed U.S. physicians (Dr. Wasef, Dr. Sakla), provider-guided care, 24hr review

Prices reflect starting rates without insurance. Actual costs may vary by plan and medication. Last updated April 2026.

Trimi: Detailed Look

Trimi

Compounded GLP-1 from $99 with US-licensed clinicians

9.2/10
Great

Pros

  • Tirzepatide at $125/month — lowest tirzepatide price among verified programs
  • Semaglutide at $99/month matches the market floor
  • US-licensed clinicians with dose-adjustment support
  • Free shipping to your door

Cons

  • New program with a short independent track record
  • No brand-name (Wegovy/Zepbound) pathway
Best For

Cash-pay users who want the cheapest tirzepatide from a US-licensed program

Yucca Health: Detailed Look

Yucca Health

LegitScript-certified GLP-1 provider with named physicians and BNPL financing

8.9/10
Excellent

Pros

  • LegitScript certified — pharmacy and telehealth verified
  • 4.6/5 Trustpilot rating from 1,000+ verified patient reviews
  • Named physicians: Dr. Michael Wasef, MD and Dr. Andrew Sakla, DO
  • Buy now, pay later via Klarna, Affirm, and Afterpay

Cons

  • Best pricing requires 6-month commitment
  • Compounded medications only — no brand-name options
Best For

Users who want a LegitScript-certified provider with verified patient reviews and flexible financing

Which Should You Choose?

The right choice depends on your specific needs and priorities. Here is a quick decision framework:

You want the lowest monthly cost

Go with Trimi at $99/month. Semaglutide $99/mo and tirzepatide $125/mo on the annual plan ($1,188 / $1,500 billed once yearly); 6-month $120 / $175, quarterly $145 / $199, month-to-month with no commitment $175 / $235. Same price at every dose, free overnight shipping, 'no hidden fees or memberships' — consultation, prescription, medication and shipping included. Verified September 6, 2026..

You want the highest-rated program

Trimi has the edge with a 9.2 rating.

You want comprehensive medical support

Compare their support: Trimi offers us-licensed clinicians, telehealth consults, dose adjustments, while Yucca Health provides licensed u.s. physicians (dr. wasef, dr. sakla), provider-guided care, 24hr review.

You are willing to invest more for premium care

Yucca Health at $125/month may offer features that justify the premium.

Trimi

Starting at $99/mo · Great

Visit Trimi

Yucca Health

Starting at $125/mo · Excellent

Read Yucca Health Review

Frequently Asked Questions

Is Trimi better than Yucca Health?

Trimi has a 9.2 rating while Yucca Health has a 8.9 rating. The better choice depends on your priorities — Trimi is best for cash-pay users who want the cheapest tirzepatide from a us-licensed program, while Yucca Health is best for users who want a legitscript-certified provider with verified patient reviews and flexible financing.

How much does Trimi cost compared to Yucca Health?

Trimi starts at $99/month (semaglutide $99/mo and tirzepatide $125/mo on the annual plan ($1,188 / $1,500 billed once yearly); 6-month $120 / $175, quarterly $145 / $199, month-to-month with no commitment $175 / $235. same price at every dose, free overnight shipping, 'no hidden fees or memberships' — consultation, prescription, medication and shipping included. verified september 6, 2026.), while Yucca Health starts at $125/month ($125/mo semaglutide and $225/mo tirzepatide on the advertised 6-month plan ($750 / $1,350 total); month-to-month runs $146 / $258. klarna/affirm/afterpay available.).

Do Trimi and Yucca Health accept insurance?

Trimi does not accept insurance. Yucca Health does not accept insurance.

Which GLP-1 medications does Trimi offer vs Yucca Health?

Trimi offers Compounded Semaglutide, Compounded Tirzepatide. Yucca Health offers Compounded Semaglutide+, Compounded Tirzepatide+.

Can I cancel Trimi or Yucca Health at any time?

Trimi allows cancel anytime. Yucca Health may have cancellation restrictions.

Are Trimi and Yucca Health available in my state?

Trimi is available in 47 states. Yucca Health is available in all 50 states.

Not sure Trimi or Yucca Health is right for you?

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