Willow vs TMates: Which GLP-1 Program Is Better? (2026)
A detailed side-by-side comparison of Willow and TMates to help you choose the right GLP-1 weight loss program based on pricing, medications, medical support, and more.
Quick Verdict
We recommend TMates
Between these two providers, TMates is our pick for most users. It offers a higher overall rating (7.8 vs 6.9), more affordable pricing, insurance acceptance. That said, Willow may be the better fit if you are looking for women who want a tablet option and 24/7 support and will pay a premium for it.
TMates scores 7.8/10 in our independent evaluation at $158/month, while Willow scores 6.9/10 at $299/month. Both programs include a licensed physician consultation and ship medication directly to your door. TMates accepts insurance, which can significantly reduce costs. Our rating considers five factors: safety and medical oversight (30%), pricing transparency (25%), cost value (20%), clinical support quality (15%), and onboarding speed (10%). We earn affiliate commissions from some providers, disclosed on this page; no provider can pay to fake safety, licensing, or hide the downsides. Prices verified April 2026.
Side-by-Side Comparison
| Feature | Willow | TMates |
|---|---|---|
| Monthly Price | $299 | $158 |
| Rating | 6.9 / 10 | 7.8 / 10 |
| Medication Type | Compounded Only | Compounded Only |
| Insurance Accepted | No | Yes |
| States Available | 38 states | 45 states |
| Consultation Fee | Free | Included |
| Shipping | Free Shipping | Free Shipping |
| Cancel Anytime | Yes | Yes |
| Medical Support | Licensed physicians, unlimited doctor access, 24/7 online care team | Licensed providers, SMS coaching, digital check-ins |
Prices reflect starting rates without insurance. Actual costs may vary by plan and medication. Last updated April 2026.
Willow: Detailed Look
Willow
Personalized GLP-1 weight loss with ongoing clinical support
Pros
- Injectable or dissolving-tablet semaglutide and tirzepatide at the same price
- Unlimited doctor access plus a 24/7 online care team
- Displays a LegitScript certification seal; HSA/FSA eligible
- Free shipping; cancel anytime (full refund if you cancel before the prescription goes to the pharmacy)
Cons
- $299/mo semaglutide and $399/mo tirzepatide — among the most expensive compounded plans we track, with no multi-month discount
- Serves 38 states — not available in AL, AK, AR, DE, KS, LA, MS, ND, RI, SD, UT or WV
- Newer platform — fewer long-term patient reviews available
Women who want a tablet option and 24/7 support and will pay a premium for it
TMates: Detailed Look
TMates
GLP-1 weight loss program that accepts major insurance plans
Pros
- One of the few GLP-1 providers that accepts major insurance
- Flat-rate pricing includes meds, consults, coaching, and delivery
- 24/7 SMS-based coaching and digital check-ins
- Phentermine option for non-GLP-1 candidates
Cons
- Relatively newer platform with limited independent reviews
- Full program details require enrollment to verify
Users with insurance who want a coached GLP-1 program with multiple medication options
Which Should You Choose?
The right choice depends on your specific needs and priorities. Here is a quick decision framework:
Go with TMates at $158/month. Compounded semaglutide from $158/mo and tirzepatide from $167/mo, all-inclusive (visits, coaching, medication). Brand Zepbound/Wegovy pathway at $99/mo with insurance coverage..
TMates has the edge with a 7.8 rating.
TMates accepts insurance, which can significantly reduce your out-of-pocket cost.
Compare their support: Willow offers licensed physicians, unlimited doctor access, 24/7 online care team, while TMates provides licensed providers, sms coaching, digital check-ins.
Willow at $299/month may offer features that justify the premium.
Frequently Asked Questions
Is Willow better than TMates?
Willow has a 6.9 rating while TMates has a 7.8 rating. The better choice depends on your priorities — Willow is best for women who want a tablet option and 24/7 support and will pay a premium for it, while TMates is best for users with insurance who want a coached glp-1 program with multiple medication options.
How much does Willow cost compared to TMates?
Willow starts at $299/month (compounded semaglutide $299/mo and tirzepatide $399/mo, billed month-to-month with no plan tiers ('one time for $299 / subscribe for $299'); the same prices apply to willow's semaglutide and tirzepatide dissolving tablets. hsa/fsa eligible, free 2-day shipping, medical evaluation included. read on startwillow.com product pages september 18, 2026 — the previous $160 'starting price' matched nothing on the site.), while TMates starts at $158/month (compounded semaglutide from $158/mo and tirzepatide from $167/mo, all-inclusive (visits, coaching, medication). brand zepbound/wegovy pathway at $99/mo with insurance coverage.).
Do Willow and TMates accept insurance?
Willow does not accept insurance. TMates accepts insurance.
Which GLP-1 medications does Willow offer vs TMates?
Willow offers Compounded Semaglutide (Injectable), Compounded Tirzepatide (Injectable), Compounded Semaglutide (Tablets), Compounded Tirzepatide (Tablets). TMates offers Compounded Semaglutide, Compounded Tirzepatide, Phentermine.
Can I cancel Willow or TMates at any time?
Willow allows cancel anytime. TMates also allows cancel anytime.
Are Willow and TMates available in my state?
Willow is available in 38 states. TMates is available in 45 states.
Not sure Willow or TMates is right for you?
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