Trimi vs TMates: Which GLP-1 Program Is Better? (2026)
A detailed side-by-side comparison of Trimi and TMates to help you choose the right GLP-1 weight loss program based on pricing, medications, medical support, and more.
Quick Verdict
We recommend Trimi
Between these two providers, Trimi is our pick for most users. It offers a higher overall rating (8.3 vs 7.8), more affordable pricing. That said, TMates may be the better fit if you are looking for users with insurance who want a coached glp-1 program with multiple medication options.
Trimi scores 8.3/10 in our independent evaluation at $99/month, while TMates scores 7.8/10 at $199/month. Both programs include a licensed physician consultation and ship medication directly to your door. Our rating considers five factors: safety and medical oversight (30%), pricing transparency (25%), cost value (20%), clinical support quality (15%), and onboarding speed (10%). This comparison was independently produced — neither provider pays for placement or higher ratings. Prices verified April 2026.
Side-by-Side Comparison
| Feature | Trimi | TMates |
|---|---|---|
| Monthly Price | $99 | $199 |
| Rating | 8.3 / 10 | 7.8 / 10 |
| Medication Type | Compounded Only | Compounded Only |
| Insurance Accepted | No | Yes |
| States Available | 47 states | 45 states |
| Consultation Fee | Included | Included |
| Shipping | Free Shipping | Free Shipping |
| Cancel Anytime | Yes | Yes |
| Medical Support | US-licensed clinicians, telehealth consults, dose adjustments | Licensed providers, SMS coaching, digital check-ins |
Prices reflect starting rates without insurance. Actual costs may vary by plan and medication. Last updated April 2026.
Trimi: Detailed Look
Trimi
Compounded GLP-1 from $99 with US-licensed clinicians
Pros
- Tirzepatide at $125/month — lowest tirzepatide price among verified programs
- Semaglutide at $99/month matches the market floor
- US-licensed clinicians with dose-adjustment support
- Free shipping to your door
Cons
- New program with a short independent track record
- No brand-name (Wegovy/Zepbound) pathway
Cash-pay users who want the cheapest tirzepatide from a US-licensed program
TMates: Detailed Look
TMates
GLP-1 weight loss program that accepts major insurance plans
Pros
- One of the few GLP-1 providers that accepts major insurance
- Flat-rate pricing includes meds, consults, coaching, and delivery
- 24/7 SMS-based coaching and digital check-ins
- Phentermine option for non-GLP-1 candidates
Cons
- Relatively newer platform with limited independent reviews
- Full program details require enrollment to verify
Users with insurance who want a coached GLP-1 program with multiple medication options
Which Should You Choose?
The right choice depends on your specific needs and priorities. Here is a quick decision framework:
Go with Trimi at $99/month. Semaglutide $99/mo; tirzepatide $125/mo — cheapest tirzepatide floor we track.
Trimi has the edge with a 8.3 rating.
TMates accepts insurance, which can significantly reduce your out-of-pocket cost.
Compare their support: Trimi offers us-licensed clinicians, telehealth consults, dose adjustments, while TMates provides licensed providers, sms coaching, digital check-ins.
TMates at $199/month may offer features that justify the premium.
Frequently Asked Questions
Is Trimi better than TMates?
Trimi has a 8.3 rating while TMates has a 7.8 rating. The better choice depends on your priorities — Trimi is best for cash-pay users who want the cheapest tirzepatide from a us-licensed program, while TMates is best for users with insurance who want a coached glp-1 program with multiple medication options.
How much does Trimi cost compared to TMates?
Trimi starts at $99/month (semaglutide $99/mo; tirzepatide $125/mo — cheapest tirzepatide floor we track), while TMates starts at $199/month ($199/mo semaglutide, $297/mo tirzepatide).
Do Trimi and TMates accept insurance?
Trimi does not accept insurance. TMates accepts insurance.
Which GLP-1 medications does Trimi offer vs TMates?
Trimi offers Compounded Semaglutide, Compounded Tirzepatide. TMates offers Compounded Semaglutide, Compounded Tirzepatide, Phentermine.
Can I cancel Trimi or TMates at any time?
Trimi allows cancel anytime. TMates also allows cancel anytime.
Are Trimi and TMates available in my state?
Trimi is available in 47 states. TMates is available in 45 states.
Not sure Trimi or TMates is right for you?
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