SynergyRx vs Yucca Health
Recorded prices, access and terms.
The short answer
- Cheapest to start, semaglutide: Only Yucca Health has a recorded semaglutide monthly-plan rate ($89/mo). SynergyRx has no semaglutide monthly-plan rate on our record.
- Cheapest to start, tirzepatide: Only Yucca Health has a recorded tirzepatide monthly-plan rate ($139/mo). SynergyRx has no tirzepatide monthly-plan rate on our record.
- Cheapest over 12 months, semaglutide: Only Yucca Health has enough on the record for a 12-month semaglutide figure: $1,068 on 12 months on the monthly plan.
- Cheapest over 12 months, tirzepatide: Only Yucca Health has enough on the record for a 12-month tirzepatide figure: $1,668 on 12 months on the monthly plan.
- Broadest availability: Yucca Health is recorded in 50 states, SynergyRx in 45.
- Drugs: SynergyRx lists brand-name and compounded medication; Yucca Health lists compounded medication only.
Price lines compare recorded monthly-plan subtotals and term totals, as on our price pages. A lower recorded rate is not a complete cost: labs, dose changes and the amount due today can differ.
Decision table
The entries below are recorded provider statements unless a regulatory source is linked. A provider webpage does not independently verify its licenses or quality. SynergyRx source · Yucca Health source.
| Compare | SynergyRx | Yucca Health |
|---|---|---|
| Recorded monthly-plan price | Not recorded | $89/mo semaglutide, $139/mo tirzepatide |
| Recorded medication/program subtotal | No monthly-plan rate is recorded. See the seller's site for current prices. The full required cost is not established. | Recorded medication and program subtotal: semaglutide: $89/month; tirzepatide: $139/month. Other required fees, labs, dose changes and renewal terms are not established. This is not a verified all-in treatment cost. |
| Lowest 12-month total on the record | No rate and term we can carry to 12 months | semaglutide $1,068 (12 months on the monthly plan); tirzepatide $1,668 (12 months on the monthly plan) |
| Full required monthly cost | Not established: consultation, labs, membership, dose changes and shipping must be checked | Not established: consultation, labs, membership, dose changes and shipping must be checked |
| Drug type listed | Brand-name and compounded | Compounded |
| Oral option | Injections only on the record | Injections only on the record |
| Consultation | Included in the record; current conditions unconfirmed | Free in the record; current conditions unconfirmed |
| Membership or program fee | Not separately recorded; do not assume zero. | Not separately recorded; do not assume zero. |
| Shipping | Recorded as included; confirm for your address | Recorded as included; confirm for your address |
| Labs | Required tests and any lab charge are not recorded. | Required tests and any lab charge are not recorded. |
| Insurance | Self-pay on the record | Self-pay on the record |
| Pharmacy license | Not independently verified. Obtain the dispensing pharmacy name and verify its state license. | Not independently verified. Obtain the dispensing pharmacy name and verify its state license. |
| Reported states | 45; confirm eligibility and clinician licensing in your state | 50; confirm eligibility and clinician licensing in your state |
| Cancellation | Cancellation reported; notice, minimum term and refund conditions unconfirmed | Commitment/restrictions reported; request the current cancellation and refund terms |
| Clinician/support as reported | Licensed providers, 24/7 messaging, unlimited check-ins | Licensed U.S. physicians (Dr. Wasef, Dr. Sakla), provider-guided care, 24hr review |
| Trustpilot | No Trustpilot profile we could quote | 4.6/5 from 1,216 reviews (read Nov 5, 2026) |
| Recorded provider check | No date recorded | 2026-11-06 |
Price by plan and term
Each rate is a per-month amount for the plan named, from the seller's own page on the date shown. A term plan's rate needs the full term; the total under it is the rate times the months.
SynergyRx
No plan rate or seller headline is on our record. See SynergyRx's site for current prices.
On November 6, 2026 synergyrx.com pointed to a domain-parking service and redirected to a domain sale listing on sedo.com, with no provider site shown. These prices are from an earlier record and could not be re-read: $200/mo semaglutide, $299-347/mo tirzepatide.
Yucca Health
| Plan or term | Semaglutide | Tirzepatide | Source and read date |
|---|---|---|---|
| Monthly plan | $89/mo | $139/mo | Yucca Health page, read Nov 6, 2026 |
| 6-month planSix-month plan totals $750/$1,350. Monthly option $146/$258. Financing is separate from cancellation or refund rights. | $125/mo$750 over 6 months | $225/mo$1,350 over 6 months | Yucca Health page, read Sep 6, 2026 |
Under a Black Friday banner on tryyucca.com (read November 6, 2026): semaglutide $89/mo billed monthly, $84 billed every 2 months, $75 on 6 months ($450), $69 on 12 months ($828); tirzepatide $139/mo billed monthly, $134, $125, $119 on the same terms. It shows these as locked in for life.
What is included
SynergyRx
Visits: consultation recorded as "Included". Care: Licensed providers, 24/7 messaging, unlimited check-ins.
Shipping: recorded as included.
Labs: Required tests and any lab charge are not recorded.
Dose increases: A price for each dose step is not recorded.
What SynergyRx lists:
- Free expedited shipping on all orders
- 24/7 support access with unlimited messaging
- Partners with multiple certified pharmacies for reliability
Yucca Health
Visits: consultation recorded as "Free". Care: Licensed U.S. physicians (Dr. Wasef, Dr. Sakla), provider-guided care, 24hr review.
Shipping: recorded as included.
Labs: Required tests and any lab charge are not recorded.
Dose increases: A price for each dose step is not recorded.
What Yucca Health lists:
- Buy now, pay later via Klarna, Affirm, and Afterpay
States served
SynergyRx: 45 states
Recorded as available in 45 states.
- May not be available in all 50 states
Yucca Health: 50 states
Recorded as available in all 50 states.
The record names no excluded state. Confirm yours at intake.
State-by-state costs and Medicaid notes are on the GLP-1 cost by state pages.
Drugs offered
SynergyRx: brand-name and compounded medication
- Compounded Semaglutide
- Compounded Tirzepatide
- Ozempic
- Wegovy
- Mounjaro
Injections only on the record.
Yucca Health: compounded medication only
- Compounded Semaglutide+
- Compounded Tirzepatide+
Injections only on the record.
Compounded drugs are made by a pharmacy for a patient and are not the brand products. Compounded vs brand-name GLP-1.
Membership and other fees
- SynergyRx: Not separately recorded; do not assume zero.
- Yucca Health: Not separately recorded; do not assume zero.
A fee missing from the record is unknown, not zero.
Cancellation and refunds
SynergyRx
Recorded as cancel anytime; notice deadlines, prepaid-plan limits and refund rights are not fully recorded.
Yucca Health
Complete notice, commitment and refund terms unknown.
Which should you choose?
SynergyRx
On the record, SynergyRx suits a reader who wants brand-name, FDA-approved medication.
Yucca Health
On the record, Yucca Health suits a reader who wants a published monthly-plan price we could record and more states on the record (50 against 45).
Ask each provider for the full cost at your prescribed dose, required labs and visits, the dispensing pharmacy, the clinician's state license, renewal charges and written refund terms. Compare those answers with your clinician.
Compounded drugs are not FDA-approved and do not undergo FDA review for safety, effectiveness or quality before marketing. FDA source and recommendations.
SynergyRx: evidence and terms
Yucca Health: evidence and terms
Price-only check 2026-11-06: Billed-monthly rates under a Black Friday banner. Longer terms are lower. Price source.
SynergyRx vs Yucca Health: questions
Which is cheaper, SynergyRx or Yucca Health?
Only Yucca Health has a recorded semaglutide monthly-plan rate ($89/mo). SynergyRx has no semaglutide monthly-plan rate on our record. Only Yucca Health has a recorded tirzepatide monthly-plan rate ($139/mo). SynergyRx has no tirzepatide monthly-plan rate on our record. These are medication and recorded program-fee subtotals; labs, dose changes and other charges may be extra.
Which costs less over a year, SynergyRx or Yucca Health?
Only Yucca Health has enough on the record for a 12-month semaglutide figure: $1,068 on 12 months on the monthly plan. Only Yucca Health has enough on the record for a 12-month tirzepatide figure: $1,668 on 12 months on the monthly plan. A term plan commits you for the full term, so check its refund rules first.
Is SynergyRx or Yucca Health available in more states?
Yucca Health is recorded in more states: 50 against 45. SynergyRx: May not be available in all 50 states. Confirm your state at intake.
Do SynergyRx and Yucca Health offer brand-name or compounded GLP-1?
SynergyRx lists brand-name and compounded medication (Compounded Semaglutide, Compounded Tirzepatide, Ozempic, Wegovy, Mounjaro). Yucca Health lists compounded medication only (Compounded Semaglutide+, Compounded Tirzepatide+). Compounded drugs are not FDA-approved.
Does SynergyRx or Yucca Health charge a membership fee?
SynergyRx: Not separately recorded; do not assume zero. Yucca Health: Not separately recorded; do not assume zero.
Can you cancel SynergyRx or Yucca Health at any time?
SynergyRx: Recorded as cancel anytime; notice deadlines, prepaid-plan limits and refund rights are not fully recorded. Yucca Health: Complete notice, commitment and refund terms unknown.
Are the visit and shipping included with SynergyRx and Yucca Health?
SynergyRx: consultation recorded as "Included", shipping recorded as included. Yucca Health: consultation recorded as "Free", shipping recorded as included.
Do SynergyRx or Yucca Health take insurance?
Neither is recorded as accepting insurance; both are self-pay on our record.
Compare the full provider directory · Compare recorded price subtotals