SkinnyRx vs Yucca Health: Which GLP-1 Program Is Better? (2026)
A detailed side-by-side comparison of SkinnyRx and Yucca Health to help you choose the right GLP-1 weight loss program based on pricing, medications, medical support, and more.
Quick Verdict
We recommend SkinnyRx
Between these two providers, SkinnyRx is our pick for most users. It offers a higher overall rating (8.5 vs 7.7). That said, Yucca Health may be the better fit if you are looking for price-sensitive users willing to commit to a 6-month plan for the lowest per-month cost.
Side-by-Side Comparison
| Feature | SkinnyRx | Yucca Health |
|---|---|---|
| Monthly Price | $199 | $146 |
| Rating | 8.5 / 10 | 7.7 / 10 |
| Medication Type | Compounded Only | Compounded Only |
| Insurance Accepted | No | No |
| States Available | 48 states | 45 states |
| Consultation Fee | Included | Free |
| Shipping | Free Shipping | Free Shipping |
| Cancel Anytime | Yes | No |
| Medical Support | Licensed U.S. physicians, 24-48hr prescription review | Licensed providers, asynchronous review |
Prices reflect starting rates without insurance. Actual costs may vary by plan and medication. Last updated March 2026.
SkinnyRx: Detailed Look
SkinnyRx
Semaglutide and tirzepatide in injectable, oral, and sublingual forms
Pros
- Three delivery forms: injectable, sublingual, and oral tablets
- Free overnight shipping from FDA-regulated U.S. pharmacies
- Month-to-month billing with no contracts
- 4.8/5 Trustpilot rating from thousands of verified reviews
Cons
- Cash-pay only — no insurance billing
- Compounded medications only — no brand-name options
Users who want multiple delivery forms (oral, sublingual, injectable) for their GLP-1
Yucca Health: Detailed Look
Yucca Health
Competitive GLP-1 pricing with fast 2-day shipping and flexible payment
Pros
- Competitive pricing on 6-month plans
- Fast UPS 2-Day Air shipping included
- Flexible payment via Affirm, Klarna, and Afterpay
- No live doctor visit required — fully asynchronous review
Cons
- Pricing only revealed after completing intake form
- Does not provide HSA/FSA receipts for reimbursement
Price-sensitive users willing to commit to a 6-month plan for the lowest per-month cost
Which Should You Choose?
The right choice depends on your specific needs and priorities. Here is a quick decision framework:
Go with Yucca Health at $146/month. $146/mo semaglutide on 6-month plan, $258/mo tirzepatide.
SkinnyRx has the edge with a 8.5 rating.
Compare their support: SkinnyRx offers licensed u.s. physicians, 24-48hr prescription review, while Yucca Health provides licensed providers, asynchronous review.
SkinnyRx at $199/month may offer features that justify the premium.
Frequently Asked Questions
Is SkinnyRx better than Yucca Health?
SkinnyRx has a 8.5 rating while Yucca Health has a 7.7 rating. The better choice depends on your priorities — SkinnyRx is best for users who want multiple delivery forms (oral, sublingual, injectable) for their glp-1, while Yucca Health is best for price-sensitive users willing to commit to a 6-month plan for the lowest per-month cost.
How much does SkinnyRx cost compared to Yucca Health?
SkinnyRx starts at $199/month ($199/mo semaglutide, up to $349/mo for tirzepatide), while Yucca Health starts at $146/month ($146/mo semaglutide on 6-month plan, $258/mo tirzepatide).
Do SkinnyRx and Yucca Health accept insurance?
SkinnyRx does not accept insurance. Yucca Health does not accept insurance.
Which GLP-1 medications does SkinnyRx offer vs Yucca Health?
SkinnyRx offers Compounded Semaglutide (Injectable), Compounded Semaglutide (Sublingual), Compounded Tirzepatide (Injectable), Compounded Tirzepatide (Tablets). Yucca Health offers Compounded Semaglutide+, Compounded Tirzepatide+.
Can I cancel SkinnyRx or Yucca Health at any time?
SkinnyRx allows cancel anytime. Yucca Health may have cancellation restrictions.
Are SkinnyRx and Yucca Health available in my state?
SkinnyRx is available in 48 states. Yucca Health is available in 45 states.