SkinnyRx vs SynergyRx
Recorded prices, access and terms.
The short answer
- Cheapest to start, semaglutide: Neither has a recorded semaglutide monthly-plan rate. The sellers' own lines read SkinnyRx: "$99 first month, renewal not published". Those terms differ, so we do not rank them.
- Cheapest to start, tirzepatide: Neither has a recorded tirzepatide monthly-plan rate. The sellers' own lines read SkinnyRx: "$99 first month, renewal not published". Those terms differ, so we do not rank them.
- Cheapest over 12 months, semaglutide: Neither record holds a rate and term we can carry to 12 months for semaglutide.
- Cheapest over 12 months, tirzepatide: Neither record holds a rate and term we can carry to 12 months for tirzepatide.
- Broadest availability: SkinnyRx is recorded in 48 states, SynergyRx in 45.
- Drugs: SkinnyRx lists compounded medication only; SynergyRx lists brand-name and compounded medication.
Price lines compare recorded monthly-plan subtotals and term totals, as on our price pages. A lower recorded rate is not a complete cost: labs, dose changes and the amount due today can differ.
Decision table
The entries below are recorded provider statements unless a regulatory source is linked. A provider webpage does not independently verify its licenses or quality. SkinnyRx source · SynergyRx source.
| Compare | SkinnyRx | SynergyRx |
|---|---|---|
| Recorded monthly-plan price | Not recorded | Not recorded |
| Recorded medication/program subtotal | Seller's headline: $99 first month for injections, tablets $149 or $199 first month, renewal price not published. It may require prepayment, a specific dose or introductory terms. The full required cost is not established. | No monthly-plan rate is recorded. See the seller's site for current prices. The full required cost is not established. |
| Lowest 12-month total on the record | No rate and term we can carry to 12 months | No rate and term we can carry to 12 months |
| Full required monthly cost | Not established: consultation, labs, membership, dose changes and shipping must be checked | Not established: consultation, labs, membership, dose changes and shipping must be checked |
| Drug type listed | Compounded | Brand-name and compounded |
| Oral option | Listed | Injections only on the record |
| Consultation | Included in the record; current conditions unconfirmed | Included in the record; current conditions unconfirmed |
| Membership or program fee | Not separately recorded; do not assume zero. | Not separately recorded; do not assume zero. |
| Shipping | Recorded as included; confirm for your address | Recorded as included; confirm for your address |
| Labs | Required tests and any lab charge are not recorded. | Required tests and any lab charge are not recorded. |
| Insurance | Self-pay on the record | Self-pay on the record |
| Pharmacy license | Not independently verified. Obtain the dispensing pharmacy name and verify its state license. | Not independently verified. Obtain the dispensing pharmacy name and verify its state license. |
| Reported states | 48; confirm eligibility and clinician licensing in your state | 45; confirm eligibility and clinician licensing in your state |
| Cancellation | Cancellation reported; notice, minimum term and refund conditions unconfirmed | Cancellation reported; notice, minimum term and refund conditions unconfirmed |
| Clinician/support as reported | Licensed U.S. physicians, 24-48hr prescription review | Licensed providers, 24/7 messaging, unlimited check-ins |
| Trustpilot | 4.8/5 from 5,401 reviews (read Nov 5, 2026) | No Trustpilot profile we could quote |
| Recorded provider check | 2026-11-06 | No date recorded |
Price by plan and term
Each rate is a per-month amount for the plan named, from the seller's own page on the date shown. A term plan's rate needs the full term; the total under it is the rate times the months.
SkinnyRx
| Plan or term | Semaglutide | Tirzepatide | Source and read date |
|---|---|---|---|
| Seller's headline | $99 first month, renewal not published | $99 first month, renewal not published | SkinnyRx page, read Nov 6, 2026 |
Last published standing prices were $199/mo injectable semaglutide and $299/mo injectable tirzepatide (seen September 1, 2026). Since September 2 the homepage, both product pages and the FAQ show only a '$99 first month' price for each injectable (tablets $149 / $199 first month) under a '$99 GLP-1 Injections: While Supplies Last' banner, with no renewal rate anywhere, so it has no standing price on record. Plans are subscriptions with no contract, cancel anytime; the refund FAQ notes promotional discounts may be reversed if you cancel before the end of a promotional term. Re-checked September 26, 2026: still only first-month prices ($99 injections 'while supplies last', tablets $149 semaglutide / $199 tirzepatide first month). Re-read November 6, 2026: unchanged.
SynergyRx
No plan rate or seller headline is on our record. See SynergyRx's site for current prices.
On November 6, 2026 synergyrx.com pointed to a domain-parking service and redirected to a domain sale listing on sedo.com, with no provider site shown. These prices are from an earlier record and could not be re-read: $200/mo semaglutide, $299-347/mo tirzepatide.
What is included
SkinnyRx
Visits: consultation recorded as "Included". Care: Licensed U.S. physicians, 24-48hr prescription review.
Shipping: recorded as included.
Labs: Required tests and any lab charge are not recorded.
Dose increases: A price for each dose step is not recorded.
What SkinnyRx lists:
- Three delivery forms: injectable, sublingual, and oral tablets
- Month-to-month billing with no contracts
How it works, per SkinnyRx's page:
- Take an online assessment of your health history, goals and preferences.
- A licensed provider reviews it and decides whether prescription treatment is appropriate.
- If prescribed, fulfillment may be pharmacy pickup or direct delivery where available.
- The care team offers in-app support and progress tracking.
SynergyRx
Visits: consultation recorded as "Included". Care: Licensed providers, 24/7 messaging, unlimited check-ins.
Shipping: recorded as included.
Labs: Required tests and any lab charge are not recorded.
Dose increases: A price for each dose step is not recorded.
What SynergyRx lists:
- Free expedited shipping on all orders
- 24/7 support access with unlimited messaging
- Partners with multiple certified pharmacies for reliability
States served
SkinnyRx: 48 states
Recorded as available in 48 states.
The record names no excluded state. Confirm yours at intake.
SynergyRx: 45 states
Recorded as available in 45 states.
- May not be available in all 50 states
State-by-state costs and Medicaid notes are on the GLP-1 cost by state pages.
Drugs offered
SkinnyRx: compounded medication only
- Compounded Semaglutide (Injectable)
- Compounded Semaglutide (Sublingual)
- Compounded Tirzepatide (Injectable)
- Compounded Tirzepatide (Tablets)
An oral form is listed.
SynergyRx: brand-name and compounded medication
- Compounded Semaglutide
- Compounded Tirzepatide
- Ozempic
- Wegovy
- Mounjaro
Injections only on the record.
Compounded drugs are made by a pharmacy for a patient and are not the brand products. Compounded vs brand-name GLP-1.
Membership and other fees
- SkinnyRx: Not separately recorded; do not assume zero.
- SynergyRx: Not separately recorded; do not assume zero.
A fee missing from the record is unknown, not zero.
Cancellation and refunds
SkinnyRx
Recorded as cancel anytime, but introductory discounts may be reversed on early cancellation. Confirm notice and refund rules.
- A full refund is available until a licensed provider completes the prescription review.
- Partially used subscription periods are not refunded as a rule, and bundled subscriptions are non-refundable.
SynergyRx
Recorded as cancel anytime; notice deadlines, prepaid-plan limits and refund rights are not fully recorded.
Which should you choose?
SkinnyRx
On the record, SkinnyRx suits a reader who wants more states on the record (48 against 45) and an oral option.
SynergyRx
On the record, SynergyRx suits a reader who wants brand-name, FDA-approved medication.
Ask each provider for the full cost at your prescribed dose, required labs and visits, the dispensing pharmacy, the clinician's state license, renewal charges and written refund terms. Compare those answers with your clinician.
Compounded drugs are not FDA-approved and do not undergo FDA review for safety, effectiveness or quality before marketing. FDA source and recommendations.
SkinnyRx: evidence and terms
Recorded FDA letter (2026-02-20): FDA found claims on skinnyrx.com for compounded GLP-1 products false or misleading, making the products misbranded under FD&C Act sections 502(a) and 502(bb). FDA letter.
SynergyRx: evidence and terms
SkinnyRx vs SynergyRx: questions
Which is cheaper, SkinnyRx or SynergyRx?
Neither has a recorded semaglutide monthly-plan rate. The sellers' own lines read SkinnyRx: "$99 first month, renewal not published". Those terms differ, so we do not rank them. Neither has a recorded tirzepatide monthly-plan rate. The sellers' own lines read SkinnyRx: "$99 first month, renewal not published". Those terms differ, so we do not rank them. These are medication and recorded program-fee subtotals; labs, dose changes and other charges may be extra.
Which costs less over a year, SkinnyRx or SynergyRx?
Neither record holds a rate and term we can carry to 12 months for semaglutide. Neither record holds a rate and term we can carry to 12 months for tirzepatide. A term plan commits you for the full term, so check its refund rules first.
Is SkinnyRx or SynergyRx available in more states?
SkinnyRx is recorded in more states: 48 against 45. SynergyRx: May not be available in all 50 states. Confirm your state at intake.
Do SkinnyRx and SynergyRx offer brand-name or compounded GLP-1?
SkinnyRx lists compounded medication only (Compounded Semaglutide (Injectable), Compounded Semaglutide (Sublingual), Compounded Tirzepatide (Injectable), Compounded Tirzepatide (Tablets)). SynergyRx lists brand-name and compounded medication (Compounded Semaglutide, Compounded Tirzepatide, Ozempic, Wegovy, Mounjaro). Compounded drugs are not FDA-approved.
Does SkinnyRx or SynergyRx charge a membership fee?
SkinnyRx: Not separately recorded; do not assume zero. SynergyRx: Not separately recorded; do not assume zero.
Can you cancel SkinnyRx or SynergyRx at any time?
SkinnyRx: Recorded as cancel anytime, but introductory discounts may be reversed on early cancellation. Confirm notice and refund rules. SynergyRx: Recorded as cancel anytime; notice deadlines, prepaid-plan limits and refund rights are not fully recorded.
Are the visit and shipping included with SkinnyRx and SynergyRx?
SkinnyRx: consultation recorded as "Included", shipping recorded as included. SynergyRx: consultation recorded as "Included", shipping recorded as included.
Do SkinnyRx or SynergyRx take insurance?
Neither is recorded as accepting insurance; both are self-pay on our record.
Does SkinnyRx or SynergyRx offer a pill or tablet?
SkinnyRx lists an oral option; SynergyRx lists injections only on our record.
Compare the full provider directory · Compare recorded price subtotals