Willow vs ShedRx: Which GLP-1 Program Is Better? (2026)
A detailed side-by-side comparison of Willow and ShedRx to help you choose the right GLP-1 weight loss program based on pricing, medications, medical support, and more.
Quick Verdict
We recommend ShedRx
Between these two providers, ShedRx is our pick for most users. It offers a higher overall rating (8.8 vs 6.9), more affordable pricing, availability in all 50 states, both brand-name and compounded medication options. That said, Willow may be the better fit if you are looking for women who want a tablet option and 24/7 support and will pay a premium for it.
ShedRx scores 8.8/10 in our independent evaluation at $159/month, while Willow scores 6.9/10 at $299/month. Both programs include a licensed physician consultation and ship medication directly to your door. ShedRx also offers oral GLP-1 options for patients who prefer pills over injections. Our rating considers five factors: safety and medical oversight (30%), pricing transparency (25%), cost value (20%), clinical support quality (15%), and onboarding speed (10%). We earn affiliate commissions from some providers, disclosed on this page; no provider can pay to fake safety, licensing, or hide the downsides. Prices verified April 2026.
Side-by-Side Comparison
| Feature | Willow | ShedRx |
|---|---|---|
| Monthly Price | $299 | $159 |
| Rating | 6.9 / 10 | 8.8 / 10 |
| Medication Type | Compounded Only | Brand & Compounded |
| Insurance Accepted | No | No |
| States Available | 38 states | All 50 states |
| Consultation Fee | Free | Included |
| Shipping | Free Shipping | Free Shipping |
| Cancel Anytime | Yes | No |
| Medical Support | Licensed physicians, unlimited doctor access, 24/7 online care team | Licensed physicians, health coaching, supplement guidance |
Prices reflect starting rates without insurance. Actual costs may vary by plan and medication. Last updated April 2026.
Willow: Detailed Look
Willow
Personalized GLP-1 weight loss with ongoing clinical support
Pros
- Injectable or dissolving-tablet semaglutide and tirzepatide at the same price
- Unlimited doctor access plus a 24/7 online care team
- Displays a LegitScript certification seal; HSA/FSA eligible
- Free shipping; cancel anytime (full refund if you cancel before the prescription goes to the pharmacy)
Cons
- $299/mo semaglutide and $399/mo tirzepatide — among the most expensive compounded plans we track, with no multi-month discount
- Serves 38 states — not available in AL, AK, AR, DE, KS, LA, MS, ND, RI, SD, UT or WV
- Newer platform — fewer long-term patient reviews available
Women who want a tablet option and 24/7 support and will pay a premium for it
ShedRx: Detailed Look
ShedRx
150K+ members with 5 medication forms — injections, oral drops, lozenges, tablets, and pills
Pros
- Most delivery forms of any provider: injections, oral drops, lozenges, tablets, and pills
- 120-day guarantee: lose 5% (or reach your goal weight) or your money back — first-time GLP-1 users, coaching and check-in conditions apply
- Both compounded and brand-name options (Wegovy, Zepbound)
- 150,000+ members, health coaching and supplements included
Cons
- 2-month minimum on every plan; the $159 rate needs a 12-month commitment ($199 month-to-month)
- Recurring Trustpilot complaints about cancellations, reaching support and unexpected charges
Users who want multiple medication delivery forms and a money-back weight loss guarantee
Which Should You Choose?
The right choice depends on your specific needs and priorities. Here is a quick decision framework:
Go with ShedRx at $159/month. Now trading as Shed (tryshed.com). Compounded semaglutide from $159/mo (12-month plan; $179 6-month, $199 monthly) and tirzepatide from $239/mo ($269 / $299). Oral options: lozenges from $199, liquid drops from $229, semaglutide tablets from $299. Brand pathway: Wegovy pill $149 / pen $199, Zepbound $349, Foundayo $149 — medication only, plus a $125/mo Shed membership. Every plan carries a 2-month minimum..
ShedRx has the edge with a 8.8 rating.
Willow focuses on compounded medications at a lower price point.
Compare their support: Willow offers licensed physicians, unlimited doctor access, 24/7 online care team, while ShedRx provides licensed physicians, health coaching, supplement guidance.
Willow at $299/month may offer features that justify the premium.
Frequently Asked Questions
Is Willow better than ShedRx?
Willow has a 6.9 rating while ShedRx has a 8.8 rating. The better choice depends on your priorities — Willow is best for women who want a tablet option and 24/7 support and will pay a premium for it, while ShedRx is best for users who want multiple medication delivery forms and a money-back weight loss guarantee.
How much does Willow cost compared to ShedRx?
Willow starts at $299/month (compounded semaglutide $299/mo and tirzepatide $399/mo, billed month-to-month with no plan tiers ('one time for $299 / subscribe for $299'); the same prices apply to willow's semaglutide and tirzepatide dissolving tablets. hsa/fsa eligible, free 2-day shipping, medical evaluation included. read on startwillow.com product pages september 18, 2026 — the previous $160 'starting price' matched nothing on the site.), while ShedRx starts at $159/month (now trading as shed (tryshed.com). compounded semaglutide from $159/mo (12-month plan; $179 6-month, $199 monthly) and tirzepatide from $239/mo ($269 / $299). oral options: lozenges from $199, liquid drops from $229, semaglutide tablets from $299. brand pathway: wegovy pill $149 / pen $199, zepbound $349, foundayo $149 — medication only, plus a $125/mo shed membership. every plan carries a 2-month minimum.).
Do Willow and ShedRx accept insurance?
Willow does not accept insurance. ShedRx does not accept insurance.
Which GLP-1 medications does Willow offer vs ShedRx?
Willow offers Compounded Semaglutide (Injectable), Compounded Tirzepatide (Injectable), Compounded Semaglutide (Tablets), Compounded Tirzepatide (Tablets). ShedRx offers Compounded Semaglutide, Compounded Tirzepatide, Wegovy, Zepbound, Foundayo (oral orforglipron).
Can I cancel Willow or ShedRx at any time?
Willow allows cancel anytime. ShedRx may have cancellation restrictions.
Are Willow and ShedRx available in my state?
Willow is available in 38 states. ShedRx is available in all 50 states.
Not sure Willow or ShedRx is right for you?
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