Trimi vs ShedRx: Which GLP-1 Program Is Better? (2026)
A detailed side-by-side comparison of Trimi and ShedRx to help you choose the right GLP-1 weight loss program based on pricing, medications, medical support, and more.
Quick Verdict
We recommend Trimi
Between these two providers, Trimi is our pick for most users. It offers a higher overall rating (9.2 vs 8.8), more affordable pricing. That said, ShedRx may be the better fit if you are looking for users who want multiple medication delivery forms and a money-back weight loss guarantee.
Trimi scores 9.2/10 in our evaluation at $99/month, while ShedRx scores 8.8/10 at $159/month. Both programs include a licensed physician consultation and ship medication directly to your door. Our rating considers five factors: safety and medical oversight (30%), pricing transparency (25%), cost value (20%), clinical support quality (15%), and onboarding speed (10%). We earn affiliate commissions from some providers, disclosed on this page; no provider can pay to fake safety, licensing, or hide the downsides. Prices verified April 2026.
Side-by-Side Comparison
| Feature | Trimi | ShedRx |
|---|---|---|
| Monthly Price | $99 | $159 |
| Rating | 9.2 / 10 | 8.8 / 10 |
| Medication Type | Compounded Only | Brand & Compounded |
| Insurance Accepted | No | No |
| States Available | 47 states | All 50 states |
| Consultation Fee | Included | Included |
| Shipping | Free Shipping | Free Shipping |
| Cancel Anytime | Yes | No |
| Medical Support | US-licensed clinicians, telehealth consults, dose adjustments | Licensed physicians, health coaching, supplement guidance |
Prices reflect starting rates without insurance. Actual costs may vary by plan and medication. Last updated April 2026.
Trimi: Detailed Look
Trimi
Compounded GLP-1 from $99 with US-licensed clinicians
Pros
- Tirzepatide at $125/month — lowest tirzepatide price among verified programs
- Semaglutide at $99/month matches the market floor
- US-licensed clinicians with dose-adjustment support
- Free shipping to your door
Cons
- New program with a short independent track record
- No brand-name (Wegovy/Zepbound) pathway
Cash-pay users who want the cheapest tirzepatide from a US-licensed program
ShedRx: Detailed Look
ShedRx
150K+ members with 5 medication forms — injections, oral drops, lozenges, tablets, and pills
Pros
- Most delivery forms of any provider: injections, oral drops, lozenges, tablets, and pills
- 120-day guarantee: lose 5% (or reach your goal weight) or your money back — first-time GLP-1 users, coaching and check-in conditions apply
- Both compounded and brand-name options (Wegovy, Zepbound)
- 150,000+ members, health coaching and supplements included
Cons
- 2-month minimum on every plan; the $159 rate needs a 12-month commitment ($199 month-to-month)
- Recurring Trustpilot complaints about cancellations, reaching support and unexpected charges
Users who want multiple medication delivery forms and a money-back weight loss guarantee
Which Should You Choose?
The right choice depends on your specific needs and priorities. Here is a quick decision framework:
Go with Trimi at $99/month. Semaglutide $99/mo and tirzepatide $125/mo on the annual plan ($1,188 / $1,500 billed once yearly); 6-month $120 / $175, quarterly $145 / $199, month-to-month with no commitment $175 / $235. Same price at every dose, free overnight shipping, 'no hidden fees or memberships' — consultation, prescription, medication and shipping included. Verified September 6, 2026..
Trimi has the edge with a 9.2 rating.
Trimi focuses on compounded medications at a lower price point.
Compare their support: Trimi offers us-licensed clinicians, telehealth consults, dose adjustments, while ShedRx provides licensed physicians, health coaching, supplement guidance.
ShedRx at $159/month may offer features that justify the premium.
Frequently Asked Questions
Is Trimi better than ShedRx?
Trimi has a 9.2 rating while ShedRx has a 8.8 rating. The better choice depends on your priorities — Trimi is best for cash-pay users who want the cheapest tirzepatide from a us-licensed program, while ShedRx is best for users who want multiple medication delivery forms and a money-back weight loss guarantee.
How much does Trimi cost compared to ShedRx?
Trimi starts at $99/month (semaglutide $99/mo and tirzepatide $125/mo on the annual plan ($1,188 / $1,500 billed once yearly); 6-month $120 / $175, quarterly $145 / $199, month-to-month with no commitment $175 / $235. same price at every dose, free overnight shipping, 'no hidden fees or memberships' — consultation, prescription, medication and shipping included. verified september 6, 2026.), while ShedRx starts at $159/month (now trading as shed (tryshed.com). compounded semaglutide from $159/mo (12-month plan; $179 6-month, $199 monthly) and tirzepatide from $239/mo ($269 / $299). oral options: lozenges from $199, liquid drops from $229, semaglutide tablets from $299. brand pathway: wegovy pill $149 / pen $199, zepbound $349, foundayo $149 — medication only, plus a $125/mo shed membership. every plan carries a 2-month minimum.).
Do Trimi and ShedRx accept insurance?
Trimi does not accept insurance. ShedRx does not accept insurance.
Which GLP-1 medications does Trimi offer vs ShedRx?
Trimi offers Compounded Semaglutide, Compounded Tirzepatide. ShedRx offers Compounded Semaglutide, Compounded Tirzepatide, Wegovy, Zepbound, Foundayo (oral orforglipron).
Can I cancel Trimi or ShedRx at any time?
Trimi allows cancel anytime. ShedRx may have cancellation restrictions.
Are Trimi and ShedRx available in my state?
Trimi is available in 47 states. ShedRx is available in all 50 states.
Not sure Trimi or ShedRx is right for you?
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