Willow vs Sesame Care: Which GLP-1 Program Is Better? (2026)
A detailed side-by-side comparison of Willow and Sesame Care to help you choose the right GLP-1 weight loss program based on pricing, medications, medical support, and more.
Quick Verdict
We recommend Sesame Care
Between these two providers, Sesame Care is our pick for most users. It offers a higher overall rating (7.2 vs 6.9), more affordable pricing, availability in all 50 states, insurance acceptance. That said, Willow may be the better fit if you are looking for women who want a tablet option and 24/7 support and will pay a premium for it.
Sesame Care scores 7.2/10 in our independent evaluation at $208/month, while Willow scores 6.9/10 at $299/month. Both programs include a licensed physician consultation and ship medication directly to your door. Sesame Care accepts insurance, which can significantly reduce costs. Sesame Care also offers oral GLP-1 options for patients who prefer pills over injections. Our rating considers five factors: safety and medical oversight (30%), pricing transparency (25%), cost value (20%), clinical support quality (15%), and onboarding speed (10%). We earn affiliate commissions from some providers, disclosed on this page; no provider can pay to fake safety, licensing, or hide the downsides. Prices verified April 2026.
Side-by-Side Comparison
| Feature | Willow | Sesame Care |
|---|---|---|
| Monthly Price | $299 | $208 |
| Rating | 6.9 / 10 | 7.2 / 10 |
| Medication Type | Compounded Only | Brand-Name Only |
| Insurance Accepted | No | Yes |
| States Available | 38 states | All 50 states |
| Consultation Fee | Free | $59/mo care subscription (12-month commitment) |
| Shipping | Free Shipping | Paid |
| Cancel Anytime | Yes | Yes |
| Medical Support | Licensed physicians, unlimited doctor access, 24/7 online care team | Licensed physicians, per-visit model |
Prices reflect starting rates without insurance. Actual costs may vary by plan and medication. Last updated April 2026.
Willow: Detailed Look
Willow
Personalized GLP-1 weight loss with ongoing clinical support
Pros
- Injectable or dissolving-tablet semaglutide and tirzepatide at the same price
- Unlimited doctor access plus a 24/7 online care team
- Displays a LegitScript certification seal; HSA/FSA eligible
- Free shipping; cancel anytime (full refund if you cancel before the prescription goes to the pharmacy)
Cons
- $299/mo semaglutide and $399/mo tirzepatide — among the most expensive compounded plans we track, with no multi-month discount
- Serves 38 states — not available in AL, AK, AR, DE, KS, LA, MS, ND, RI, SD, UT or WV
- Newer platform — fewer long-term patient reviews available
Women who want a tablet option and 24/7 support and will pay a premium for it
Sesame Care: Detailed Look
Sesame Care
Affordable telehealth marketplace connecting patients with doctors from $25
Pros
- Lowest consultation cost — visits from just $25
- Prescribes brand-name FDA-approved medications
- Transparent pricing: a $59/mo care subscription plus the manufacturer's own medication price
- Wide network of licensed physicians across all 50 states
Cons
- Medication cost is separate and not included in visit fee
- No compounded options — brand-name only (higher drug cost)
People who specifically want brand-name FDA-approved GLP-1s and will commit to a year of care — not the cheapest route, and no compounded option
Which Should You Choose?
The right choice depends on your specific needs and priorities. Here is a quick decision framework:
Go with Sesame Care at $208/month. Sesame has moved to a "Success by Sesame" subscription: $59/mo for care (priced on a 12-month commitment) plus medication billed separately — Wegovy from $149/mo brings the all-in to roughly $208/mo, and Zepbound from $299/mo to roughly $358/mo. Brand-name FDA-approved medication only; Sesame no longer offers a compounded option, so it does not appear in our compounded price ladders. Sesame notes medication pricing may vary by treatment, dose, pharmacy and provider, so these are floors rather than guarantees. Verified August 31, 2026..
Sesame Care has the edge with a 7.2 rating.
Sesame Care accepts insurance, which can significantly reduce your out-of-pocket cost.
Choose Sesame Care which exclusively prescribes brand-name medications.
Willow focuses on compounded medications at a lower price point.
Compare their support: Willow offers licensed physicians, unlimited doctor access, 24/7 online care team, while Sesame Care provides licensed physicians, per-visit model.
Willow at $299/month may offer features that justify the premium.
Frequently Asked Questions
Is Willow better than Sesame Care?
Willow has a 6.9 rating while Sesame Care has a 7.2 rating. The better choice depends on your priorities — Willow is best for women who want a tablet option and 24/7 support and will pay a premium for it, while Sesame Care is best for people who specifically want brand-name fda-approved glp-1s and will commit to a year of care — not the cheapest route, and no compounded option.
How much does Willow cost compared to Sesame Care?
Willow starts at $299/month (compounded semaglutide $299/mo and tirzepatide $399/mo, billed month-to-month with no plan tiers ('one time for $299 / subscribe for $299'); the same prices apply to willow's semaglutide and tirzepatide dissolving tablets. hsa/fsa eligible, free 2-day shipping, medical evaluation included. read on startwillow.com product pages september 18, 2026 — the previous $160 'starting price' matched nothing on the site.), while Sesame Care starts at $208/month (sesame has moved to a "success by sesame" subscription: $59/mo for care (priced on a 12-month commitment) plus medication billed separately — wegovy from $149/mo brings the all-in to roughly $208/mo, and zepbound from $299/mo to roughly $358/mo. brand-name fda-approved medication only; sesame no longer offers a compounded option, so it does not appear in our compounded price ladders. sesame notes medication pricing may vary by treatment, dose, pharmacy and provider, so these are floors rather than guarantees. verified august 31, 2026.).
Do Willow and Sesame Care accept insurance?
Willow does not accept insurance. Sesame Care accepts insurance.
Which GLP-1 medications does Willow offer vs Sesame Care?
Willow offers Compounded Semaglutide (Injectable), Compounded Tirzepatide (Injectable), Compounded Semaglutide (Tablets), Compounded Tirzepatide (Tablets). Sesame Care offers Wegovy, Wegovy HD, Wegovy (oral), Zepbound, Zepbound KwikPen, Foundayo.
Can I cancel Willow or Sesame Care at any time?
Willow allows cancel anytime. Sesame Care also allows cancel anytime.
Are Willow and Sesame Care available in my state?
Willow is available in 38 states. Sesame Care is available in all 50 states.
Not sure Willow or Sesame Care is right for you?
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