Telos Rx vs Sesame Care: Which GLP-1 Program Is Better? (2026)
A detailed side-by-side comparison of Telos Rx and Sesame Care to help you choose the right GLP-1 weight loss program based on pricing, medications, medical support, and more.
Quick Verdict
We recommend Telos Rx
Between these two providers, Telos Rx is our pick for most users. It offers a higher overall rating (8.2 vs 7.2), more affordable pricing. That said, Sesame Care may be the better fit if you are looking for people who specifically want brand-name fda-approved glp-1s and will commit to a year of care — not the cheapest route, and no compounded option.
Telos Rx scores 8.2/10 in our evaluation at $99/month, while Sesame Care scores 7.2/10 at $208/month. Both programs include a licensed physician consultation and ship medication directly to your door. Telos Rx also offers oral GLP-1 options for patients who prefer pills over injections. Our rating considers five factors: safety and medical oversight (30%), pricing transparency (25%), cost value (20%), clinical support quality (15%), and onboarding speed (10%). We earn affiliate commissions from some providers, disclosed on this page; no provider can pay to fake safety, licensing, or hide the downsides. Prices verified April 2026.
Side-by-Side Comparison
| Feature | Telos Rx | Sesame Care |
|---|---|---|
| Monthly Price | $99 | $208 |
| Rating | 8.2 / 10 | 7.2 / 10 |
| Medication Type | Compounded Only | Brand-Name Only |
| Insurance Accepted | No | Yes |
| States Available | 47 states | All 50 states |
| Consultation Fee | Included | $59/mo care subscription (12-month commitment) |
| Shipping | Free Shipping | Paid |
| Cancel Anytime | Yes | Yes |
| Medical Support | Licensed prescribers, telehealth consults | Licensed physicians, per-visit model |
Prices reflect starting rates without insurance. Actual costs may vary by plan and medication. Last updated April 2026.
Telos Rx: Detailed Look
Telos Rx
Tirzepatide-first program with oral and injection options
Pros
- Tirzepatide-specialist program (most competitors lead with semaglutide)
- Oral tirzepatide option — rare among verified programs
- Entry pricing from $99
- FDA-registered US compounding pharmacy sourcing
Cons
- Higher-dose tirzepatide plans reach $399/month
- New program with limited review history
Users specifically seeking tirzepatide — especially the oral format
Sesame Care: Detailed Look
Sesame Care
Affordable telehealth marketplace connecting patients with doctors from $25
Pros
- Lowest consultation cost — visits from just $25
- Prescribes brand-name FDA-approved medications
- Transparent pricing: a $59/mo care subscription plus the manufacturer's own medication price
- Wide network of licensed physicians across all 50 states
Cons
- Medication cost is separate and not included in visit fee
- No compounded options — brand-name only (higher drug cost)
People who specifically want brand-name FDA-approved GLP-1s and will commit to a year of care — not the cheapest route, and no compounded option
Which Should You Choose?
The right choice depends on your specific needs and priorities. Here is a quick decision framework:
Go with Telos Rx at $99/month. Semaglutide as low as $99/mo, tirzepatide $139/mo, microdosed tirzepatide $116/mo, oral GLP-1 from $9/day. Flat pricing — the monthly cost stays the same as your dose goes up. LegitScript certified..
Telos Rx has the edge with a 8.2 rating.
Sesame Care accepts insurance, which can significantly reduce your out-of-pocket cost.
Choose Sesame Care which exclusively prescribes brand-name medications.
Telos Rx focuses on compounded medications at a lower price point.
Compare their support: Telos Rx offers licensed prescribers, telehealth consults, while Sesame Care provides licensed physicians, per-visit model.
Sesame Care at $208/month may offer features that justify the premium.
Frequently Asked Questions
Is Telos Rx better than Sesame Care?
Telos Rx has a 8.2 rating while Sesame Care has a 7.2 rating. The better choice depends on your priorities — Telos Rx is best for users specifically seeking tirzepatide — especially the oral format, while Sesame Care is best for people who specifically want brand-name fda-approved glp-1s and will commit to a year of care — not the cheapest route, and no compounded option.
How much does Telos Rx cost compared to Sesame Care?
Telos Rx starts at $99/month (semaglutide as low as $99/mo, tirzepatide $139/mo, microdosed tirzepatide $116/mo, oral glp-1 from $9/day. flat pricing — the monthly cost stays the same as your dose goes up. legitscript certified.), while Sesame Care starts at $208/month (sesame has moved to a "success by sesame" subscription: $59/mo for care (priced on a 12-month commitment) plus medication billed separately — wegovy from $149/mo brings the all-in to roughly $208/mo, and zepbound from $299/mo to roughly $358/mo. brand-name fda-approved medication only; sesame no longer offers a compounded option, so it does not appear in our compounded price ladders. sesame notes medication pricing may vary by treatment, dose, pharmacy and provider, so these are floors rather than guarantees. verified august 31, 2026.).
Do Telos Rx and Sesame Care accept insurance?
Telos Rx does not accept insurance. Sesame Care accepts insurance.
Which GLP-1 medications does Telos Rx offer vs Sesame Care?
Telos Rx offers Compounded Tirzepatide, Compounded Semaglutide, Oral Tirzepatide. Sesame Care offers Wegovy, Wegovy HD, Wegovy (oral), Zepbound, Zepbound KwikPen, Foundayo.
Can I cancel Telos Rx or Sesame Care at any time?
Telos Rx allows cancel anytime. Sesame Care also allows cancel anytime.
Are Telos Rx and Sesame Care available in my state?
Telos Rx is available in 47 states. Sesame Care is available in all 50 states.
Not sure Telos Rx or Sesame Care is right for you?
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