Sesame Care vs SynergyRx
Recorded prices, access and terms.
The short answer
- Cheapest to start, semaglutide: Neither has a semaglutide monthly-plan rate on our record. Price on seller's site.
- Cheapest to start, tirzepatide: Neither has a tirzepatide monthly-plan rate on our record. Price on seller's site.
- Cheapest over 12 months, semaglutide: Neither record holds a rate and term we can carry to 12 months for semaglutide.
- Cheapest over 12 months, tirzepatide: Neither record holds a rate and term we can carry to 12 months for tirzepatide.
- Broadest availability: Sesame Care is recorded in 50 states, SynergyRx in 45.
- Drugs: Sesame Care lists brand-name medication only; SynergyRx lists brand-name and compounded medication.
Price lines compare recorded monthly-plan subtotals and term totals, as on our price pages. A lower recorded rate is not a complete cost: labs, dose changes and the amount due today can differ.
Decision table
The entries below are recorded provider statements unless a regulatory source is linked. A provider webpage does not independently verify its licenses or quality. Sesame Care source · SynergyRx source.
| Compare | Sesame Care | SynergyRx |
|---|---|---|
| Recorded monthly-plan price | Not recorded | Not recorded |
| Recorded medication/program subtotal | Seller's headline: $59/mo care on a 12-month plan, plus brand medication from $149/mo, billed separately. It may require prepayment, a specific dose or introductory terms. The full required cost is not established. | No monthly-plan rate is recorded. See the seller's site for current prices. The full required cost is not established. |
| Lowest 12-month total on the record | No rate and term we can carry to 12 months | No rate and term we can carry to 12 months |
| Full required monthly cost | Not established: consultation, labs, membership, dose changes and shipping must be checked | Not established: consultation, labs, membership, dose changes and shipping must be checked |
| Drug type listed | Brand-name | Brand-name and compounded |
| Oral option | Listed | Injections only on the record |
| Consultation | $59/mo care subscription (12-month commitment) in the record; current conditions unconfirmed | Included in the record; current conditions unconfirmed |
| Membership or program fee | From $59 a month on an annual plan, or $99 month to month. It covers telehealth visits, messaging and ongoing care. Medication is paid separately, from $149 a month. (Sesame's page, read Nov 6, 2026) | Not separately recorded; do not assume zero. |
| Shipping | Charge not recorded | Recorded as included; confirm for your address |
| Labs | Required tests and any lab charge are not recorded. | Required tests and any lab charge are not recorded. |
| Insurance | Recorded as accepted | Self-pay on the record |
| Pharmacy license | Not independently verified. Obtain the dispensing pharmacy name and verify its state license. | Not independently verified. Obtain the dispensing pharmacy name and verify its state license. |
| Reported states | 50; confirm eligibility and clinician licensing in your state | 45; confirm eligibility and clinician licensing in your state |
| Cancellation | Cancellation reported; notice, minimum term and refund conditions unconfirmed | Cancellation reported; notice, minimum term and refund conditions unconfirmed |
| Clinician/support as reported | Licensed physicians, per-visit model | Licensed providers, 24/7 messaging, unlimited check-ins |
| Trustpilot | 4.6/5 from 4,607 reviews (read Nov 5, 2026) | No Trustpilot profile we could quote |
| Recorded provider check | 2026-11-06 | No date recorded |
Price by plan and term
Each rate is a per-month amount for the plan named, from the seller's own page on the date shown. A term plan's rate needs the full term; the total under it is the rate times the months.
Sesame Care
| Plan or term | Semaglutide | Tirzepatide | Source and read date |
|---|---|---|---|
| Seller's headline$59/mo care on a 12-month plan, plus brand medication from $149/mo, billed separately | See the plan note | See the plan note | Sesame Care page, read Nov 6, 2026 |
Brand-name FDA-approved medication only; Sesame no longer offers a compounded option, so it has no compounded price. Sesame notes medication pricing may vary by treatment, dose, pharmacy and provider, so these are floors rather than guarantees. Read August 31, 2026.
SynergyRx
No plan rate or seller headline is on our record. See SynergyRx's site for current prices.
On November 6, 2026 synergyrx.com pointed to a domain-parking service and redirected to a domain sale listing on sedo.com, with no provider site shown. These prices are from an earlier record and could not be re-read: $200/mo semaglutide, $299-347/mo tirzepatide.
What is included
Sesame Care
Visits: consultation recorded as "$59/mo care subscription (12-month commitment)". Care: Licensed physicians, per-visit model.
Shipping: a shipping charge is not recorded.
Labs: Required tests and any lab charge are not recorded.
Dose increases: A price for each dose step is not recorded.
What Sesame Care lists:
- Prescribes brand-name FDA-approved medications
SynergyRx
Visits: consultation recorded as "Included". Care: Licensed providers, 24/7 messaging, unlimited check-ins.
Shipping: recorded as included.
Labs: Required tests and any lab charge are not recorded.
Dose increases: A price for each dose step is not recorded.
What SynergyRx lists:
- Free expedited shipping on all orders
- 24/7 support access with unlimited messaging
- Partners with multiple certified pharmacies for reliability
States served
Sesame Care: 50 states
Recorded as available in all 50 states.
- Wide network of licensed physicians across all 50 states
SynergyRx: 45 states
Recorded as available in 45 states.
- May not be available in all 50 states
State-by-state costs and Medicaid notes are on the GLP-1 cost by state pages.
Drugs offered
Sesame Care: brand-name medication only
- Wegovy
- Wegovy HD
- Wegovy (oral)
- Zepbound
- Zepbound KwikPen
- Foundayo
An oral form is listed.
SynergyRx: brand-name and compounded medication
- Compounded Semaglutide
- Compounded Tirzepatide
- Ozempic
- Wegovy
- Mounjaro
Injections only on the record.
Compounded drugs are made by a pharmacy for a patient and are not the brand products. Compounded vs brand-name GLP-1.
Membership and other fees
- Sesame Care: From $59 a month on an annual plan, or $99 month to month. It covers telehealth visits, messaging and ongoing care. Medication is paid separately, from $149 a month. (Sesame's page, read Nov 6, 2026)
- SynergyRx: Not separately recorded; do not assume zero.
A fee missing from the record is unknown, not zero.
Cancellation and refunds
Sesame Care
Recorded as cancel anytime; notice deadlines, prepaid-plan limits and refund rights are not fully recorded.
SynergyRx
Recorded as cancel anytime; notice deadlines, prepaid-plan limits and refund rights are not fully recorded.
Which should you choose?
Sesame Care
On the record, Sesame Care suits a reader who wants more states on the record (50 against 45), an oral option and insurance use.
SynergyRx
On the record, SynergyRx suits a reader who wants compounded medication, no separate membership fee on the record and shipping recorded as included.
Ask each provider for the full cost at your prescribed dose, required labs and visits, the dispensing pharmacy, the clinician's state license, renewal charges and written refund terms. Compare those answers with your clinician.
Compounded drugs are not FDA-approved and do not undergo FDA review for safety, effectiveness or quality before marketing. FDA source and recommendations.
Sesame Care: evidence and terms
SynergyRx: evidence and terms
Sesame Care vs SynergyRx: questions
Which is cheaper, Sesame Care or SynergyRx?
Neither has a semaglutide monthly-plan rate on our record. Price on seller's site. Neither has a tirzepatide monthly-plan rate on our record. Price on seller's site. These are medication and recorded program-fee subtotals; labs, dose changes and other charges may be extra.
Which costs less over a year, Sesame Care or SynergyRx?
Neither record holds a rate and term we can carry to 12 months for semaglutide. Neither record holds a rate and term we can carry to 12 months for tirzepatide. A term plan commits you for the full term, so check its refund rules first.
Is Sesame Care or SynergyRx available in more states?
Sesame Care is recorded in more states: 50 against 45. Sesame Care: Wide network of licensed physicians across all 50 states. SynergyRx: May not be available in all 50 states. Confirm your state at intake.
Do Sesame Care and SynergyRx offer brand-name or compounded GLP-1?
Sesame Care lists brand-name medication only (Wegovy, Wegovy HD, Wegovy (oral), Zepbound, Zepbound KwikPen, Foundayo). SynergyRx lists brand-name and compounded medication (Compounded Semaglutide, Compounded Tirzepatide, Ozempic, Wegovy, Mounjaro). Compounded drugs are not FDA-approved.
Does Sesame Care or SynergyRx charge a membership fee?
Sesame Care: From $59 a month on an annual plan, or $99 month to month. It covers telehealth visits, messaging and ongoing care. Medication is paid separately, from $149 a month. (Sesame's page, read Nov 6, 2026) SynergyRx: Not separately recorded; do not assume zero.
Can you cancel Sesame Care or SynergyRx at any time?
Sesame Care: Recorded as cancel anytime; notice deadlines, prepaid-plan limits and refund rights are not fully recorded. SynergyRx: Recorded as cancel anytime; notice deadlines, prepaid-plan limits and refund rights are not fully recorded.
Are the visit and shipping included with Sesame Care and SynergyRx?
Sesame Care: consultation recorded as "$59/mo care subscription (12-month commitment)", shipping charge not recorded. SynergyRx: consultation recorded as "Included", shipping recorded as included.
Do Sesame Care or SynergyRx take insurance?
Sesame Care is recorded as accepting insurance; SynergyRx is self-pay on our record.
Does Sesame Care or SynergyRx offer a pill or tablet?
Sesame Care lists an oral option; SynergyRx lists injections only on our record.
Compare the full provider directory · Compare recorded price subtotals