SkinnyRx vs Sesame Care: Which GLP-1 Program Is Better? (2026)
A detailed side-by-side comparison of SkinnyRx and Sesame Care to help you choose the right GLP-1 weight loss program based on pricing, medications, medical support, and more.
Quick Verdict
We recommend SkinnyRx
Between these two providers, SkinnyRx is our pick for most users. It offers a higher overall rating (8.9 vs 7.2), more affordable pricing. That said, Sesame Care may be the better fit if you are looking for people who specifically want brand-name fda-approved glp-1s and will commit to a year of care — not the cheapest route, and no compounded option.
SkinnyRx scores 8.9/10 in our independent evaluation at $199/month, while Sesame Care scores 7.2/10 at $208/month. Both programs include a licensed physician consultation and ship medication directly to your door. SkinnyRx also offers oral GLP-1 options for patients who prefer pills over injections. Our rating considers five factors: safety and medical oversight (30%), pricing transparency (25%), cost value (20%), clinical support quality (15%), and onboarding speed (10%). We earn affiliate commissions from some providers, disclosed on this page; no provider can pay to fake safety, licensing, or hide the downsides. Prices verified April 2026.
Side-by-Side Comparison
| Feature | SkinnyRx | Sesame Care |
|---|---|---|
| Monthly Price | $199 | $208 |
| Rating | 8.9 / 10 | 7.2 / 10 |
| Medication Type | Compounded Only | Brand-Name Only |
| Insurance Accepted | No | Yes |
| States Available | 48 states | All 50 states |
| Consultation Fee | Included | $59/mo care subscription (12-month commitment) |
| Shipping | Free Shipping | Paid |
| Cancel Anytime | Yes | Yes |
| Medical Support | Licensed U.S. physicians, 24-48hr prescription review | Licensed physicians, per-visit model |
Prices reflect starting rates without insurance. Actual costs may vary by plan and medication. Last updated April 2026.
SkinnyRx: Detailed Look
SkinnyRx
Fastest-growing GLP-1 provider — oral, sublingual, and injectable options with Affirm financing
Pros
- Three delivery forms: injectable, sublingual, and oral tablets
- Free overnight shipping from FDA-regulated U.S. pharmacies
- Month-to-month billing with no contracts
- 4.8/5 Trustpilot rating from thousands of verified reviews
Cons
- Cash-pay only — no insurance billing
- Compounded medications only — no brand-name options
Users who want multiple delivery forms (oral, sublingual, injectable) for their GLP-1
Sesame Care: Detailed Look
Sesame Care
Affordable telehealth marketplace connecting patients with doctors from $25
Pros
- Lowest consultation cost — visits from just $25
- Prescribes brand-name FDA-approved medications
- Transparent pricing: a $59/mo care subscription plus the manufacturer's own medication price
- Wide network of licensed physicians across all 50 states
Cons
- Medication cost is separate and not included in visit fee
- No compounded options — brand-name only (higher drug cost)
People who specifically want brand-name FDA-approved GLP-1s and will commit to a year of care — not the cheapest route, and no compounded option
Which Should You Choose?
The right choice depends on your specific needs and priorities. Here is a quick decision framework:
Go with SkinnyRx at $199/month. Last published standing prices were $199/mo injectable semaglutide and $299/mo injectable tirzepatide (seen September 1, 2026). Since September 2 the homepage, both product pages and the FAQ show only a '$99 first month' price for each injectable (tablets $149 / $199 first month) under a '$99 GLP-1 Injections: While Supplies Last' banner, with no renewal rate anywhere — so SkinnyRx is excluded from our verified price ladders until a standing price is republished. Plans are subscriptions with no contract, cancel anytime; the refund FAQ notes promotional discounts may be reversed if you cancel before the end of a promotional term. Re-checked September 26, 2026: still only first-month prices ($99 injections 'while supplies last', tablets $149 semaglutide / $199 tirzepatide first month)..
SkinnyRx has the edge with a 8.9 rating.
Sesame Care accepts insurance, which can significantly reduce your out-of-pocket cost.
Choose Sesame Care which exclusively prescribes brand-name medications.
SkinnyRx focuses on compounded medications at a lower price point.
Compare their support: SkinnyRx offers licensed u.s. physicians, 24-48hr prescription review, while Sesame Care provides licensed physicians, per-visit model.
Sesame Care at $208/month may offer features that justify the premium.
Frequently Asked Questions
Is SkinnyRx better than Sesame Care?
SkinnyRx has a 8.9 rating while Sesame Care has a 7.2 rating. The better choice depends on your priorities — SkinnyRx is best for users who want multiple delivery forms (oral, sublingual, injectable) for their glp-1, while Sesame Care is best for people who specifically want brand-name fda-approved glp-1s and will commit to a year of care — not the cheapest route, and no compounded option.
How much does SkinnyRx cost compared to Sesame Care?
SkinnyRx starts at $199/month (last published standing prices were $199/mo injectable semaglutide and $299/mo injectable tirzepatide (seen september 1, 2026). since september 2 the homepage, both product pages and the faq show only a '$99 first month' price for each injectable (tablets $149 / $199 first month) under a '$99 glp-1 injections: while supplies last' banner, with no renewal rate anywhere — so skinnyrx is excluded from our verified price ladders until a standing price is republished. plans are subscriptions with no contract, cancel anytime; the refund faq notes promotional discounts may be reversed if you cancel before the end of a promotional term. re-checked september 26, 2026: still only first-month prices ($99 injections 'while supplies last', tablets $149 semaglutide / $199 tirzepatide first month).), while Sesame Care starts at $208/month (sesame has moved to a "success by sesame" subscription: $59/mo for care (priced on a 12-month commitment) plus medication billed separately — wegovy from $149/mo brings the all-in to roughly $208/mo, and zepbound from $299/mo to roughly $358/mo. brand-name fda-approved medication only; sesame no longer offers a compounded option, so it does not appear in our compounded price ladders. sesame notes medication pricing may vary by treatment, dose, pharmacy and provider, so these are floors rather than guarantees. verified august 31, 2026.).
Do SkinnyRx and Sesame Care accept insurance?
SkinnyRx does not accept insurance. Sesame Care accepts insurance.
Which GLP-1 medications does SkinnyRx offer vs Sesame Care?
SkinnyRx offers Compounded Semaglutide (Injectable), Compounded Semaglutide (Sublingual), Compounded Tirzepatide (Injectable), Compounded Tirzepatide (Tablets). Sesame Care offers Wegovy, Wegovy HD, Wegovy (oral), Zepbound, Zepbound KwikPen, Foundayo.
Can I cancel SkinnyRx or Sesame Care at any time?
SkinnyRx allows cancel anytime. Sesame Care also allows cancel anytime.
Are SkinnyRx and Sesame Care available in my state?
SkinnyRx is available in 48 states. Sesame Care is available in all 50 states.
Not sure SkinnyRx or Sesame Care is right for you?
Answer 6 questions and we'll match you with the best program for your budget and goals.