ShedRx vs Sesame Care: Which GLP-1 Program Is Better? (2026)
A detailed side-by-side comparison of ShedRx and Sesame Care to help you choose the right GLP-1 weight loss program based on pricing, medications, medical support, and more.
Quick Verdict
We recommend ShedRx
Between these two providers, ShedRx is our pick for most users. It offers a higher overall rating (8.8 vs 7.2), more affordable pricing, both brand-name and compounded medication options. That said, Sesame Care may be the better fit if you are looking for people who specifically want brand-name fda-approved glp-1s and will commit to a year of care — not the cheapest route, and no compounded option.
ShedRx scores 8.8/10 in our evaluation at $159/month, while Sesame Care scores 7.2/10 at $208/month. Both programs include a licensed physician consultation and ship medication directly to your door. ShedRx also offers oral GLP-1 options for patients who prefer pills over injections. Our rating considers five factors: safety and medical oversight (30%), pricing transparency (25%), cost value (20%), clinical support quality (15%), and onboarding speed (10%). We earn affiliate commissions from some providers, disclosed on this page; no provider can pay to fake safety, licensing, or hide the downsides. Prices verified April 2026.
Side-by-Side Comparison
| Feature | ShedRx | Sesame Care |
|---|---|---|
| Monthly Price | $159 | $208 |
| Rating | 8.8 / 10 | 7.2 / 10 |
| Medication Type | Brand & Compounded | Brand-Name Only |
| Insurance Accepted | No | Yes |
| States Available | All 50 states | All 50 states |
| Consultation Fee | Included | $59/mo care subscription (12-month commitment) |
| Shipping | Free Shipping | Paid |
| Cancel Anytime | No | Yes |
| Medical Support | Licensed physicians, health coaching, supplement guidance | Licensed physicians, per-visit model |
Prices reflect starting rates without insurance. Actual costs may vary by plan and medication. Last updated April 2026.
ShedRx: Detailed Look
ShedRx
150K+ members with 5 medication forms — injections, oral drops, lozenges, tablets, and pills
Pros
- Most delivery forms of any provider: injections, oral drops, lozenges, tablets, and pills
- 120-day guarantee: lose 5% (or reach your goal weight) or your money back — first-time GLP-1 users, coaching and check-in conditions apply
- Both compounded and brand-name options (Wegovy, Zepbound)
- 150,000+ members, health coaching and supplements included
Cons
- 2-month minimum on every plan; the $159 rate needs a 12-month commitment ($199 month-to-month)
- Recurring Trustpilot complaints about cancellations, reaching support and unexpected charges
Users who want multiple medication delivery forms and a money-back weight loss guarantee
Sesame Care: Detailed Look
Sesame Care
Affordable telehealth marketplace connecting patients with doctors from $25
Pros
- Lowest consultation cost — visits from just $25
- Prescribes brand-name FDA-approved medications
- Transparent pricing: a $59/mo care subscription plus the manufacturer's own medication price
- Wide network of licensed physicians across all 50 states
Cons
- Medication cost is separate and not included in visit fee
- No compounded options — brand-name only (higher drug cost)
People who specifically want brand-name FDA-approved GLP-1s and will commit to a year of care — not the cheapest route, and no compounded option
Which Should You Choose?
The right choice depends on your specific needs and priorities. Here is a quick decision framework:
Go with ShedRx at $159/month. Now trading as Shed (tryshed.com). Compounded semaglutide from $159/mo (12-month plan; $179 6-month, $199 monthly) and tirzepatide from $239/mo ($269 / $299). Oral options: lozenges from $199, liquid drops from $229, semaglutide tablets from $299. Brand pathway: Wegovy pill $149 / pen $199, Zepbound $349, Foundayo $149 — medication only, plus a $125/mo Shed membership. Every plan carries a 2-month minimum..
ShedRx has the edge with a 8.8 rating.
Sesame Care accepts insurance, which can significantly reduce your out-of-pocket cost.
Choose Sesame Care which exclusively prescribes brand-name medications.
Compare their support: ShedRx offers licensed physicians, health coaching, supplement guidance, while Sesame Care provides licensed physicians, per-visit model.
Sesame Care at $208/month may offer features that justify the premium.
Frequently Asked Questions
Is ShedRx better than Sesame Care?
ShedRx has a 8.8 rating while Sesame Care has a 7.2 rating. The better choice depends on your priorities — ShedRx is best for users who want multiple medication delivery forms and a money-back weight loss guarantee, while Sesame Care is best for people who specifically want brand-name fda-approved glp-1s and will commit to a year of care — not the cheapest route, and no compounded option.
How much does ShedRx cost compared to Sesame Care?
ShedRx starts at $159/month (now trading as shed (tryshed.com). compounded semaglutide from $159/mo (12-month plan; $179 6-month, $199 monthly) and tirzepatide from $239/mo ($269 / $299). oral options: lozenges from $199, liquid drops from $229, semaglutide tablets from $299. brand pathway: wegovy pill $149 / pen $199, zepbound $349, foundayo $149 — medication only, plus a $125/mo shed membership. every plan carries a 2-month minimum.), while Sesame Care starts at $208/month (sesame has moved to a "success by sesame" subscription: $59/mo for care (priced on a 12-month commitment) plus medication billed separately — wegovy from $149/mo brings the all-in to roughly $208/mo, and zepbound from $299/mo to roughly $358/mo. brand-name fda-approved medication only; sesame no longer offers a compounded option, so it does not appear in our compounded price ladders. sesame notes medication pricing may vary by treatment, dose, pharmacy and provider, so these are floors rather than guarantees. verified august 31, 2026.).
Do ShedRx and Sesame Care accept insurance?
ShedRx does not accept insurance. Sesame Care accepts insurance.
Which GLP-1 medications does ShedRx offer vs Sesame Care?
ShedRx offers Compounded Semaglutide, Compounded Tirzepatide, Wegovy, Zepbound, Foundayo (oral orforglipron). Sesame Care offers Wegovy, Wegovy HD, Wegovy (oral), Zepbound, Zepbound KwikPen, Foundayo.
Can I cancel ShedRx or Sesame Care at any time?
ShedRx may have cancellation restrictions. Sesame Care also allows cancel anytime.
Are ShedRx and Sesame Care available in my state?
ShedRx is available in all 50 states. Sesame Care is available in all 50 states.
Not sure ShedRx or Sesame Care is right for you?
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