Telos Rx vs PlexusDx: Which GLP-1 Program Is Better? (2026)
A detailed side-by-side comparison of Telos Rx and PlexusDx to help you choose the right GLP-1 weight loss program based on pricing, medications, medical support, and more.
Quick Verdict
We recommend Telos Rx
Between these two providers, Telos Rx is our pick for most users. It offers a higher overall rating (8.2 vs 7.6), more affordable pricing. That said, PlexusDx may be the better fit if you are looking for users who want one all-inclusive price that never changes with dose, and are curious about an optional genetic report.
Telos Rx scores 8.2/10 in our evaluation at $99/month, while PlexusDx scores 7.6/10 at $149/month. Both programs include a licensed physician consultation and ship medication directly to your door. Telos Rx also offers oral GLP-1 options for patients who prefer pills over injections. Our rating considers five factors: safety and medical oversight (30%), pricing transparency (25%), cost value (20%), clinical support quality (15%), and onboarding speed (10%). We earn affiliate commissions from some providers, disclosed on this page; no provider can pay to fake safety, licensing, or hide the downsides. Prices verified April 2026.
Side-by-Side Comparison
| Feature | Telos Rx | PlexusDx |
|---|---|---|
| Monthly Price | $99 | $149 |
| Rating | 8.2 / 10 | 7.6 / 10 |
| Medication Type | Compounded Only | Compounded Only |
| Insurance Accepted | No | No |
| States Available | 47 states | All 50 states |
| Consultation Fee | Included | Included |
| Shipping | Free Shipping | Free Shipping |
| Cancel Anytime | Yes | Yes |
| Medical Support | Licensed prescribers, telehealth consults | US-licensed clinicians (LionMD network) via async intake, monthly check-ins and provider-reviewed refills; five states require a scheduled video consultation |
Prices reflect starting rates without insurance. Actual costs may vary by plan and medication. Last updated April 2026.
Telos Rx: Detailed Look
Telos Rx
Tirzepatide-first program with oral and injection options
Pros
- Tirzepatide-specialist program (most competitors lead with semaglutide)
- Oral tirzepatide option — rare among verified programs
- Entry pricing from $99
- FDA-registered US compounding pharmacy sourcing
Cons
- Higher-dose tirzepatide plans reach $399/month
- New program with limited review history
Users specifically seeking tirzepatide — especially the oral format
PlexusDx: Detailed Look
PlexusDx
All-inclusive compounded GLP-1 with flat pricing at every dose and an optional genetic test
Pros
- All-inclusive pricing with no membership fee: consult, prescription, medication, supplies and shipping in one monthly charge
- Flat price at every dose level, so the monthly cost does not rise as your dose is titrated up
- LegitScript certified (September 18, 2026), with its 503A compounding pharmacies named on the site
- Available in all 50 states, with injection, oral and low-dose microdose options
Cons
- Compounded medications are not FDA-approved
- Month-to-month pricing ($189 semaglutide, $289 tirzepatide) is well above the cheapest programs; the lower rates need a 3- or 6-month commitment
- No published refund policy, and the genetic test is an extra $99 that does not decide which medication you get
Users who want one all-inclusive price that never changes with dose, and are curious about an optional genetic report
Which Should You Choose?
The right choice depends on your specific needs and priorities. Here is a quick decision framework:
Go with Telos Rx at $99/month. Semaglutide as low as $99/mo, tirzepatide $139/mo, microdosed tirzepatide $116/mo, oral GLP-1 from $9/day. Flat pricing — the monthly cost stays the same as your dose goes up. LegitScript certified..
Telos Rx has the edge with a 8.2 rating.
Compare their support: Telos Rx offers licensed prescribers, telehealth consults, while PlexusDx provides us-licensed clinicians (lionmd network) via async intake, monthly check-ins and provider-reviewed refills; five states require a scheduled video consultation.
PlexusDx at $149/month may offer features that justify the premium.
Frequently Asked Questions
Is Telos Rx better than PlexusDx?
Telos Rx has a 8.2 rating while PlexusDx has a 7.6 rating. The better choice depends on your priorities — Telos Rx is best for users specifically seeking tirzepatide — especially the oral format, while PlexusDx is best for users who want one all-inclusive price that never changes with dose, and are curious about an optional genetic report.
How much does Telos Rx cost compared to PlexusDx?
Telos Rx starts at $99/month (semaglutide as low as $99/mo, tirzepatide $139/mo, microdosed tirzepatide $116/mo, oral glp-1 from $9/day. flat pricing — the monthly cost stays the same as your dose goes up. legitscript certified.), while PlexusDx starts at $149/month (compounded semaglutide injections $189/mo month-to-month, $169/mo on the 3-month plan and $149/mo on the 6-month plan; compounded tirzepatide injections $289 / $269 / $249. oral semaglutide runs $289 / $269 / $249 and oral tirzepatide $349 / $299 / $279; a low-dose microdose glp-1 program is $129/mo. each price is all-inclusive (provider consult, prescription, medication, supplies and shipping), stays the same at every dose level, and carries no membership fee; nothing is charged until a provider approves the prescription. the site does not say whether the 3- and 6-month tiers are billed up front. an optional glp-1 & peptide pathways genetic test is offered for $99 (list $298) after the first program order. verified october 3, 2026.).
Do Telos Rx and PlexusDx accept insurance?
Telos Rx does not accept insurance. PlexusDx does not accept insurance.
Which GLP-1 medications does Telos Rx offer vs PlexusDx?
Telos Rx offers Compounded Tirzepatide, Compounded Semaglutide, Oral Tirzepatide. PlexusDx offers Compounded Semaglutide, Compounded Semaglutide (oral), Compounded Tirzepatide, Compounded Tirzepatide (oral), Microdose GLP-1.
Can I cancel Telos Rx or PlexusDx at any time?
Telos Rx allows cancel anytime. PlexusDx also allows cancel anytime.
Are Telos Rx and PlexusDx available in my state?
Telos Rx is available in 47 states. PlexusDx is available in all 50 states.
Not sure Telos Rx or PlexusDx is right for you?
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