Strut Health vs PlexusDx: Which GLP-1 Program Is Better? (2026)

A detailed side-by-side comparison of Strut Health and PlexusDx to help you choose the right GLP-1 weight loss program based on pricing, medications, medical support, and more.

Eduard Cristea
Eduard Cristea
Dr. A. Goher, MD
Medically reviewed by Dr. A. Goher, MD
Published:

Quick Verdict

We recommend Strut Health

Between these two providers, Strut Health is our pick for most users. It offers a higher overall rating (8.2 vs 7.6), more affordable pricing. That said, PlexusDx may be the better fit if you are looking for users who want one all-inclusive price that never changes with dose, and are curious about an optional genetic report.

Strut Health scores 8.2/10 in our evaluation at $129/month, while PlexusDx scores 7.6/10 at $149/month. Both programs include a licensed physician consultation and ship medication directly to your door. Strut Health also offers oral GLP-1 options for patients who prefer pills over injections. Our rating considers five factors: safety and medical oversight (30%), pricing transparency (25%), cost value (20%), clinical support quality (15%), and onboarding speed (10%). We earn affiliate commissions from some providers, disclosed on this page; no provider can pay to fake safety, licensing, or hide the downsides. Prices verified April 2026.

Side-by-Side Comparison

Monthly Price
Strut Health
PlexusDx
Rating
Strut Health
8.2 / 10
PlexusDx
7.6 / 10
Medication Type
Strut Health
Compounded Only
PlexusDx
Compounded Only
Insurance Accepted
Strut Health
No
PlexusDx
No
States Available
Strut Health
49 states
PlexusDx
All 50 states
Consultation Fee
Strut Health
Free
PlexusDx
Included
Shipping
Strut Health
Free Shipping
PlexusDx
Free Shipping
Cancel Anytime
Strut Health
Yes
PlexusDx
Yes
Medical Support
Strut Health
Licensed physicians, ongoing follow-ups
PlexusDx
US-licensed clinicians (LionMD network) via async intake, monthly check-ins and provider-reviewed refills; five states require a scheduled video consultation

Prices reflect starting rates without insurance. Actual costs may vary by plan and medication. Last updated April 2026.

Strut Health: Detailed Look

Strut Health

Custom-compounded semaglutide in oral lozenges and injectable forms

8.2/10
Good

Pros

  • Oral semaglutide lozenge option — no needles required
  • Free consultations and follow-ups with no hidden fees
  • 2-day express shipping on initial orders
  • Cancel or pause anytime from your dashboard

Cons

  • Does not accept insurance — cash-pay or HSA/FSA only
  • No tirzepatide option currently available
Best For

Users who prefer a needle-free oral semaglutide option at a reasonable price

PlexusDx: Detailed Look

PlexusDx

All-inclusive compounded GLP-1 with flat pricing at every dose and an optional genetic test

7.6/10
Good

Pros

  • All-inclusive pricing with no membership fee: consult, prescription, medication, supplies and shipping in one monthly charge
  • Flat price at every dose level, so the monthly cost does not rise as your dose is titrated up
  • LegitScript certified (September 18, 2026), with its 503A compounding pharmacies named on the site
  • Available in all 50 states, with injection, oral and low-dose microdose options

Cons

  • Compounded medications are not FDA-approved
  • Month-to-month pricing ($189 semaglutide, $289 tirzepatide) is well above the cheapest programs; the lower rates need a 3- or 6-month commitment
  • No published refund policy, and the genetic test is an extra $99 that does not decide which medication you get
Best For

Users who want one all-inclusive price that never changes with dose, and are curious about an optional genetic report

Which Should You Choose?

The right choice depends on your specific needs and priorities. Here is a quick decision framework:

You want the lowest monthly cost

Go with Strut Health at $129/month. Compounded semaglutide $129/mo (injectable or daily oral lozenge); free physician visits, follow-ups, and shipping included..

You want the highest-rated program

Strut Health has the edge with a 8.2 rating.

You want comprehensive medical support

Compare their support: Strut Health offers licensed physicians, ongoing follow-ups, while PlexusDx provides us-licensed clinicians (lionmd network) via async intake, monthly check-ins and provider-reviewed refills; five states require a scheduled video consultation.

You are willing to invest more for premium care

PlexusDx at $149/month may offer features that justify the premium.

Strut Health

Starting at $129/mo · Good

Visit Strut Health

PlexusDx

Starting at $149/mo · Good

Visit PlexusDx

Frequently Asked Questions

Is Strut Health better than PlexusDx?

Strut Health has a 8.2 rating while PlexusDx has a 7.6 rating. The better choice depends on your priorities — Strut Health is best for users who prefer a needle-free oral semaglutide option at a reasonable price, while PlexusDx is best for users who want one all-inclusive price that never changes with dose, and are curious about an optional genetic report.

How much does Strut Health cost compared to PlexusDx?

Strut Health starts at $129/month (compounded semaglutide $129/mo (injectable or daily oral lozenge); free physician visits, follow-ups, and shipping included.), while PlexusDx starts at $149/month (compounded semaglutide injections $189/mo month-to-month, $169/mo on the 3-month plan and $149/mo on the 6-month plan; compounded tirzepatide injections $289 / $269 / $249. oral semaglutide runs $289 / $269 / $249 and oral tirzepatide $349 / $299 / $279; a low-dose microdose glp-1 program is $129/mo. each price is all-inclusive (provider consult, prescription, medication, supplies and shipping), stays the same at every dose level, and carries no membership fee; nothing is charged until a provider approves the prescription. the site does not say whether the 3- and 6-month tiers are billed up front. an optional glp-1 & peptide pathways genetic test is offered for $99 (list $298) after the first program order. verified october 3, 2026.).

Do Strut Health and PlexusDx accept insurance?

Strut Health does not accept insurance. PlexusDx does not accept insurance.

Which GLP-1 medications does Strut Health offer vs PlexusDx?

Strut Health offers Compounded Semaglutide (Injectable), Compounded Semaglutide (Oral Lozenge). PlexusDx offers Compounded Semaglutide, Compounded Semaglutide (oral), Compounded Tirzepatide, Compounded Tirzepatide (oral), Microdose GLP-1.

Can I cancel Strut Health or PlexusDx at any time?

Strut Health allows cancel anytime. PlexusDx also allows cancel anytime.

Are Strut Health and PlexusDx available in my state?

Strut Health is available in 49 states. PlexusDx is available in all 50 states.

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