Noom Med vs PlexusDx: Which GLP-1 Program Is Better? (2026)

A detailed side-by-side comparison of Noom Med and PlexusDx to help you choose the right GLP-1 weight loss program based on pricing, medications, medical support, and more.

Eduard Cristea
Eduard Cristea
Dr. A. Goher, MD
Medically reviewed by Dr. A. Goher, MD
Published:

Quick Verdict

We recommend Noom Med

Between these two providers, Noom Med is our pick for most users. It offers a higher overall rating (8 vs 7.6), insurance acceptance, both brand-name and compounded medication options. That said, PlexusDx may be the better fit if you are looking for users who want one all-inclusive price that never changes with dose, and are curious about an optional genetic report.

Noom Med scores 8/10 in our evaluation at $249/month, while PlexusDx scores 7.6/10 at $149/month. Both programs include a licensed physician consultation and ship medication directly to your door. Noom Med accepts insurance, which can significantly reduce costs. Noom Med also offers oral GLP-1 options for patients who prefer pills over injections. Our rating considers five factors: safety and medical oversight (30%), pricing transparency (25%), cost value (20%), clinical support quality (15%), and onboarding speed (10%). We earn affiliate commissions from some providers, disclosed on this page; no provider can pay to fake safety, licensing, or hide the downsides. Prices verified April 2026.

Side-by-Side Comparison

Monthly Price
Noom Med
PlexusDx
Rating
Noom Med
8 / 10
PlexusDx
7.6 / 10
Medication Type
Noom Med
Brand & Compounded
PlexusDx
Compounded Only
Insurance Accepted
Noom Med
Yes
PlexusDx
No
States Available
Noom Med
47 states
PlexusDx
All 50 states
Consultation Fee
Noom Med
$0
PlexusDx
Included
Shipping
Noom Med
Free Shipping
PlexusDx
Free Shipping
Cancel Anytime
Noom Med
No
PlexusDx
Yes
Medical Support
Noom Med
Licensed clinicians paired with the Noom coaching app
PlexusDx
US-licensed clinicians (LionMD network) via async intake, monthly check-ins and provider-reviewed refills; five states require a scheduled video consultation

Prices reflect starting rates without insurance. Actual costs may vary by plan and medication. Last updated April 2026.

Noom Med: Detailed Look

Noom Med

GLP-1 medication bundled with Noom's behavior-change coaching app

8/10
Very Good

Pros

  • Bundles compounded GLP-1 medication, clinical care, and Noom's behavior-change app in one price
  • Lower-cost microdose tier from $179/mo for budget or gentler titration
  • Branded-medication pathway lets you use insurance for Wegovy or Zepbound
  • Established, psychology-based coaching app layered on top of the medication

Cons

  • Billed quarterly in 12-week cycles — not truly month-to-month, and cancelling mid-cycle still owes the current 12 weeks
  • All-in price is far higher than pure compounders like Embody
  • Compounded semaglutide and tirzepatide are not FDA-approved finished drugs
  • Not available in every state — confirm availability before signing up
Best For

people who want GLP-1 medication bundled with a structured behavior-change app and coaching

PlexusDx: Detailed Look

PlexusDx

All-inclusive compounded GLP-1 with flat pricing at every dose and an optional genetic test

7.6/10
Good

Pros

  • All-inclusive pricing with no membership fee: consult, prescription, medication, supplies and shipping in one monthly charge
  • Flat price at every dose level, so the monthly cost does not rise as your dose is titrated up
  • LegitScript certified (September 18, 2026), with its 503A compounding pharmacies named on the site
  • Available in all 50 states, with injection, oral and low-dose microdose options

Cons

  • Compounded medications are not FDA-approved
  • Month-to-month pricing ($189 semaglutide, $289 tirzepatide) is well above the cheapest programs; the lower rates need a 3- or 6-month commitment
  • No published refund policy, and the genetic test is an extra $99 that does not decide which medication you get
Best For

Users who want one all-inclusive price that never changes with dose, and are curious about an optional genetic report

Which Should You Choose?

The right choice depends on your specific needs and priorities. Here is a quick decision framework:

You want the lowest monthly cost

Go with PlexusDx at $149/month. Compounded semaglutide injections $189/mo month-to-month, $169/mo on the 3-month plan and $149/mo on the 6-month plan; compounded tirzepatide injections $289 / $269 / $249. Oral semaglutide runs $289 / $269 / $249 and oral tirzepatide $349 / $299 / $279; a low-dose Microdose GLP-1 program is $129/mo. Each price is all-inclusive (provider consult, prescription, medication, supplies and shipping), stays the same at every dose level, and carries no membership fee; nothing is charged until a provider approves the prescription. The site does not say whether the 3- and 6-month tiers are billed up front. An optional GLP-1 & Peptide Pathways genetic test is offered for $99 (list $298) after the first program order. Verified October 3, 2026..

You want the highest-rated program

Noom Med has the edge with a 8 rating.

You have insurance coverage

Noom Med accepts insurance, which can significantly reduce your out-of-pocket cost.

You want affordable compounded options

PlexusDx focuses on compounded medications at a lower price point.

You want comprehensive medical support

Compare their support: Noom Med offers licensed clinicians paired with the noom coaching app, while PlexusDx provides us-licensed clinicians (lionmd network) via async intake, monthly check-ins and provider-reviewed refills; five states require a scheduled video consultation.

You are willing to invest more for premium care

Noom Med at $249/month may offer features that justify the premium.

Noom Med

Starting at $249/mo · Very Good

Read Noom Med Review

PlexusDx

Starting at $149/mo · Good

Visit PlexusDx

Frequently Asked Questions

Is Noom Med better than PlexusDx?

Noom Med has a 8 rating while PlexusDx has a 7.6 rating. The better choice depends on your priorities — Noom Med is best for people who want glp-1 medication bundled with a structured behavior-change app and coaching, while PlexusDx is best for users who want one all-inclusive price that never changes with dose, and are curious about an optional genetic report.

How much does Noom Med cost compared to PlexusDx?

Noom Med starts at $249/month (glp-1rx (full-dose compounded semaglutide) is $249/mo after a $129 first-month intro; compounded tirzepatide (glp-1rx plus) $299/mo after $149; the microdose tier is $179/mo after a $79 intro (was $49 in august). billed in 12-week cycles, so it is not truly month-to-month; the glp-1rx plan page quotes $279/mo ($837 per 12 weeks) against $249 on the pricing page. the branded-medication plan listed in august is no longer on the pricing page. read on noom.com september 28, 2026.), while PlexusDx starts at $149/month (compounded semaglutide injections $189/mo month-to-month, $169/mo on the 3-month plan and $149/mo on the 6-month plan; compounded tirzepatide injections $289 / $269 / $249. oral semaglutide runs $289 / $269 / $249 and oral tirzepatide $349 / $299 / $279; a low-dose microdose glp-1 program is $129/mo. each price is all-inclusive (provider consult, prescription, medication, supplies and shipping), stays the same at every dose level, and carries no membership fee; nothing is charged until a provider approves the prescription. the site does not say whether the 3- and 6-month tiers are billed up front. an optional glp-1 & peptide pathways genetic test is offered for $99 (list $298) after the first program order. verified october 3, 2026.).

Do Noom Med and PlexusDx accept insurance?

Noom Med accepts insurance. PlexusDx does not accept insurance.

Which GLP-1 medications does Noom Med offer vs PlexusDx?

Noom Med offers Compounded Semaglutide, Compounded Tirzepatide, Wegovy, Zepbound, Ozempic. PlexusDx offers Compounded Semaglutide, Compounded Semaglutide (oral), Compounded Tirzepatide, Compounded Tirzepatide (oral), Microdose GLP-1.

Can I cancel Noom Med or PlexusDx at any time?

Noom Med may have cancellation restrictions. PlexusDx also allows cancel anytime.

Are Noom Med and PlexusDx available in my state?

Noom Med is available in 47 states. PlexusDx is available in all 50 states.

Not sure Noom Med or PlexusDx is right for you?

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