Yucca Health vs MyStart Health: Which GLP-1 Program Is Better? (2026)
A detailed side-by-side comparison of Yucca Health and MyStart Health to help you choose the right GLP-1 weight loss program based on pricing, medications, medical support, and more.
Quick Verdict
We recommend Yucca Health
Between these two providers, Yucca Health is our pick for most users. It offers a higher overall rating (9.3 vs 8.5), more affordable pricing. That said, MyStart Health may be the better fit if you are looking for users who value a money-back weight-loss guarantee and price-lock protection.
Yucca Health scores 9.3/10 in our independent evaluation at $146/month, while MyStart Health scores 8.5/10 at $224/month. Both programs include a licensed physician consultation and ship medication directly to your door. Our rating considers five factors: safety and medical oversight (30%), pricing transparency (25%), cost value (20%), clinical support quality (15%), and onboarding speed (10%). We earn affiliate commissions from some providers, disclosed on this page; no provider can pay to fake safety, licensing, or hide the downsides. Prices verified April 2026.
Side-by-Side Comparison
| Feature | Yucca Health | MyStart Health |
|---|---|---|
| Monthly Price | $146 | $224 |
| Rating | 9.3 / 10 | 8.5 / 10 |
| Medication Type | Compounded Only | Brand & Compounded |
| Insurance Accepted | No | No |
| States Available | All 50 states | All 50 states |
| Consultation Fee | Free | Free |
| Shipping | Free Shipping | Free Shipping |
| Cancel Anytime | No | Yes |
| Medical Support | Licensed U.S. physicians (Dr. Wasef, Dr. Sakla), provider-guided care, 24hr review | Licensed U.S. physicians, unlimited clinician access |
Prices reflect starting rates without insurance. Actual costs may vary by plan and medication. Last updated April 2026.
Yucca Health: Detailed Look
Yucca Health
LegitScript-certified GLP-1 provider with named physicians and BNPL financing
Pros
- LegitScript certified — pharmacy and telehealth verified
- 4.6/5 Trustpilot rating from 1,000+ verified patient reviews
- Named physicians: Dr. Michael Wasef, MD and Dr. Andrew Sakla, DO
- Buy now, pay later via Klarna, Affirm, and Afterpay
Cons
- Best pricing requires 6-month commitment
- Compounded medications only — no brand-name options
Users who want a LegitScript-certified provider with verified patient reviews and flexible financing
MyStart Health: Detailed Look
MyStart Health
GLP-1 programs with a price-lock guarantee and weight-loss promise
Pros
- Price Lock Guarantee — your rate never increases with dosage
- 10% bodyweight loss in 4 months or money back
- All-inclusive pricing with free shipping and labs
- Available in all 50 states with 24-hour consultation turnaround
Cons
- Some reports of shipping and fulfillment delays
- Tirzepatide option is significantly more expensive at $429/month
Users who value a money-back weight-loss guarantee and price-lock protection
Which Should You Choose?
The right choice depends on your specific needs and priorities. Here is a quick decision framework:
Go with Yucca Health at $146/month. $146/mo month-to-month semaglutide, or $125/mo on the 6-month plan ($750 total); tirzepatide $258/mo month-to-month or $225/mo on the 6-month plan. Klarna/Affirm/Afterpay available..
Yucca Health has the edge with a 9.3 rating.
Yucca Health focuses on compounded medications at a lower price point.
Compare their support: Yucca Health offers licensed u.s. physicians (dr. wasef, dr. sakla), provider-guided care, 24hr review, while MyStart Health provides licensed u.s. physicians, unlimited clinician access.
MyStart Health at $224/month may offer features that justify the premium.
Frequently Asked Questions
Is Yucca Health better than MyStart Health?
Yucca Health has a 9.3 rating while MyStart Health has a 8.5 rating. The better choice depends on your priorities — Yucca Health is best for users who want a legitscript-certified provider with verified patient reviews and flexible financing, while MyStart Health is best for users who value a money-back weight-loss guarantee and price-lock protection.
How much does Yucca Health cost compared to MyStart Health?
Yucca Health starts at $146/month ($146/mo month-to-month semaglutide, or $125/mo on the 6-month plan ($750 total); tirzepatide $258/mo month-to-month or $225/mo on the 6-month plan. klarna/affirm/afterpay available.), while MyStart Health starts at $224/month ($299/mo (use code selflove25 for 25% off = $224/mo). includes meds, labs, shipping, unlimited clinician access).
Do Yucca Health and MyStart Health accept insurance?
Yucca Health does not accept insurance. MyStart Health does not accept insurance.
Which GLP-1 medications does Yucca Health offer vs MyStart Health?
Yucca Health offers Compounded Semaglutide+, Compounded Tirzepatide+. MyStart Health offers Compounded Semaglutide, Compounded Tirzepatide, Ozempic, Wegovy.
Can I cancel Yucca Health or MyStart Health at any time?
Yucca Health may have cancellation restrictions. MyStart Health also allows cancel anytime.
Are Yucca Health and MyStart Health available in my state?
Yucca Health is available in all 50 states. MyStart Health is available in all 50 states.
Not sure Yucca Health or MyStart Health is right for you?
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