MyStart Health vs Yucca Health: Which GLP-1 Program Is Better? (2026)

A detailed side-by-side comparison of MyStart Health and Yucca Health to help you choose the right GLP-1 weight loss program based on pricing, medications, medical support, and more.

Eduard Cristea
Eduard Cristea
Dr. A. Goher, MD
Medically reviewed by Dr. A. Goher, MD
Published:

Quick Verdict

We recommend Yucca Health

Between these two providers, Yucca Health is our pick for most users. It offers a higher overall rating (9.2 vs 8.5), more affordable pricing. That said, MyStart Health may be the better fit if you are looking for users who value a money-back weight-loss guarantee and price-lock protection.

Yucca Health scores 9.2/10 in our independent evaluation at $146/month, while MyStart Health scores 8.5/10 at $224/month. Both programs include a licensed physician consultation and ship medication directly to your door. Our rating considers five factors: safety and medical oversight (30%), pricing transparency (25%), cost value (20%), clinical support quality (15%), and onboarding speed (10%). This comparison was independently produced — neither provider pays for placement or higher ratings. Prices verified April 2026.

Side-by-Side Comparison

FeatureMyStart HealthYucca Health
Monthly Price$224$146
Rating8.5 / 109.2 / 10
Medication TypeBrand & CompoundedCompounded Only
Insurance AcceptedNoNo
States AvailableAll 50 statesAll 50 states
Consultation FeeFreeFree
ShippingFree ShippingFree Shipping
Cancel AnytimeYesNo
Medical SupportLicensed U.S. physicians, unlimited clinician accessLicensed U.S. physicians (Dr. Wasef, Dr. Sakla), provider-guided care, 24hr review

Prices reflect starting rates without insurance. Actual costs may vary by plan and medication. Last updated April 2026.

MyStart Health: Detailed Look

MyStart Health

GLP-1 programs with a price-lock guarantee and weight-loss promise

8.5/10
Excellent

Pros

  • Price Lock Guarantee — your rate never increases with dosage
  • 10% bodyweight loss in 4 months or money back
  • All-inclusive pricing with free shipping and labs
  • Available in all 50 states with 24-hour consultation turnaround

Cons

  • Some reports of shipping and fulfillment delays
  • Tirzepatide option is significantly more expensive at $429/month
Best For

Users who value a money-back weight-loss guarantee and price-lock protection

Yucca Health: Detailed Look

Yucca Health

LegitScript-certified GLP-1 provider with named physicians and BNPL financing

9.2/10
Excellent

Pros

  • LegitScript certified — pharmacy and telehealth verified
  • 4.6/5 Trustpilot rating from 1,000+ verified patient reviews
  • Named physicians: Dr. Michael Wasef, MD and Dr. Andrew Sakla, DO
  • Buy now, pay later via Klarna, Affirm, and Afterpay

Cons

  • Best pricing requires 6-month commitment
  • Compounded medications only — no brand-name options
Best For

Users who want a LegitScript-certified provider with verified patient reviews and flexible financing

Which Should You Choose?

The right choice depends on your specific needs and priorities. Here is a quick decision framework:

You want the lowest monthly cost

Go with Yucca Health at $146/month. $146/mo semaglutide on 6-month plan, $258/mo tirzepatide. Klarna/Affirm/Afterpay available..

You want the highest-rated program

Yucca Health has the edge with a 9.2 rating.

You want affordable compounded options

Yucca Health focuses on compounded medications at a lower price point.

You want comprehensive medical support

Compare their support: MyStart Health offers licensed u.s. physicians, unlimited clinician access, while Yucca Health provides licensed u.s. physicians (dr. wasef, dr. sakla), provider-guided care, 24hr review.

You are willing to invest more for premium care

MyStart Health at $224/month may offer features that justify the premium.

MyStart Health

Starting at $224/mo · Excellent

Visit MyStart Health

Yucca Health

Starting at $146/mo · Excellent

Visit Yucca Health

Frequently Asked Questions

Is MyStart Health better than Yucca Health?

MyStart Health has a 8.5 rating while Yucca Health has a 9.2 rating. The better choice depends on your priorities — MyStart Health is best for users who value a money-back weight-loss guarantee and price-lock protection, while Yucca Health is best for users who want a legitscript-certified provider with verified patient reviews and flexible financing.

How much does MyStart Health cost compared to Yucca Health?

MyStart Health starts at $224/month ($299/mo (use code selflove25 for 25% off = $224/mo). includes meds, labs, shipping, unlimited clinician access), while Yucca Health starts at $146/month ($146/mo semaglutide on 6-month plan, $258/mo tirzepatide. klarna/affirm/afterpay available.).

Do MyStart Health and Yucca Health accept insurance?

MyStart Health does not accept insurance. Yucca Health does not accept insurance.

Which GLP-1 medications does MyStart Health offer vs Yucca Health?

MyStart Health offers Compounded Semaglutide, Compounded Tirzepatide, Ozempic, Wegovy. Yucca Health offers Compounded Semaglutide+, Compounded Tirzepatide+.

Can I cancel MyStart Health or Yucca Health at any time?

MyStart Health allows cancel anytime. Yucca Health may have cancellation restrictions.

Are MyStart Health and Yucca Health available in my state?

MyStart Health is available in all 50 states. Yucca Health is available in all 50 states.