MyStart Health vs SkinnyRx: Which GLP-1 Program Is Better? (2026)
A detailed side-by-side comparison of MyStart Health and SkinnyRx to help you choose the right GLP-1 weight loss program based on pricing, medications, medical support, and more.
Quick Verdict
We recommend SkinnyRx
Between these two providers, SkinnyRx is our pick for most users. It offers a higher overall rating (9.1 vs 8.5), more affordable pricing. That said, MyStart Health may be the better fit if you are looking for users who value a money-back weight-loss guarantee and price-lock protection.
SkinnyRx scores 9.1/10 in our independent evaluation at $199/month, while MyStart Health scores 8.5/10 at $224/month. Both programs include a licensed physician consultation and ship medication directly to your door. SkinnyRx also offers oral GLP-1 options for patients who prefer pills over injections. Our rating considers five factors: safety and medical oversight (30%), pricing transparency (25%), cost value (20%), clinical support quality (15%), and onboarding speed (10%). This comparison was independently produced — neither provider pays for placement or higher ratings. Prices verified April 2026.
Side-by-Side Comparison
| Feature | MyStart Health | SkinnyRx |
|---|---|---|
| Monthly Price | $224 | $199 |
| Rating | 8.5 / 10 | 9.1 / 10 |
| Medication Type | Brand & Compounded | Compounded Only |
| Insurance Accepted | No | No |
| States Available | All 50 states | 48 states |
| Consultation Fee | Free | Included |
| Shipping | Free Shipping | Free Shipping |
| Cancel Anytime | Yes | Yes |
| Medical Support | Licensed U.S. physicians, unlimited clinician access | Licensed U.S. physicians, 24-48hr prescription review |
Prices reflect starting rates without insurance. Actual costs may vary by plan and medication. Last updated April 2026.
MyStart Health: Detailed Look
MyStart Health
GLP-1 programs with a price-lock guarantee and weight-loss promise
Pros
- Price Lock Guarantee — your rate never increases with dosage
- 10% bodyweight loss in 4 months or money back
- All-inclusive pricing with free shipping and labs
- Available in all 50 states with 24-hour consultation turnaround
Cons
- Some reports of shipping and fulfillment delays
- Tirzepatide option is significantly more expensive at $429/month
Users who value a money-back weight-loss guarantee and price-lock protection
SkinnyRx: Detailed Look
SkinnyRx
Fastest-growing GLP-1 provider — oral, sublingual, and injectable options with Affirm financing
Pros
- Three delivery forms: injectable, sublingual, and oral tablets
- Free overnight shipping from FDA-regulated U.S. pharmacies
- Month-to-month billing with no contracts
- 4.8/5 Trustpilot rating from thousands of verified reviews
Cons
- Cash-pay only — no insurance billing
- Compounded medications only — no brand-name options
Users who want multiple delivery forms (oral, sublingual, injectable) for their GLP-1
Which Should You Choose?
The right choice depends on your specific needs and priorities. Here is a quick decision framework:
Go with SkinnyRx at $199/month. $199/mo semaglutide, up to $349/mo for tirzepatide.
SkinnyRx has the edge with a 9.1 rating.
SkinnyRx focuses on compounded medications at a lower price point.
Compare their support: MyStart Health offers licensed u.s. physicians, unlimited clinician access, while SkinnyRx provides licensed u.s. physicians, 24-48hr prescription review.
MyStart Health at $224/month may offer features that justify the premium.
Frequently Asked Questions
Is MyStart Health better than SkinnyRx?
MyStart Health has a 8.5 rating while SkinnyRx has a 9.1 rating. The better choice depends on your priorities — MyStart Health is best for users who value a money-back weight-loss guarantee and price-lock protection, while SkinnyRx is best for users who want multiple delivery forms (oral, sublingual, injectable) for their glp-1.
How much does MyStart Health cost compared to SkinnyRx?
MyStart Health starts at $224/month ($299/mo (use code selflove25 for 25% off = $224/mo). includes meds, labs, shipping, unlimited clinician access), while SkinnyRx starts at $199/month ($199/mo semaglutide, up to $349/mo for tirzepatide).
Do MyStart Health and SkinnyRx accept insurance?
MyStart Health does not accept insurance. SkinnyRx does not accept insurance.
Which GLP-1 medications does MyStart Health offer vs SkinnyRx?
MyStart Health offers Compounded Semaglutide, Compounded Tirzepatide, Ozempic, Wegovy. SkinnyRx offers Compounded Semaglutide (Injectable), Compounded Semaglutide (Sublingual), Compounded Tirzepatide (Injectable), Compounded Tirzepatide (Tablets).
Can I cancel MyStart Health or SkinnyRx at any time?
MyStart Health allows cancel anytime. SkinnyRx also allows cancel anytime.
Are MyStart Health and SkinnyRx available in my state?
MyStart Health is available in all 50 states. SkinnyRx is available in 48 states.
Not sure MyStart Health or SkinnyRx is right for you?
Answer 6 questions and we'll match you with the best program for your budget and goals.