MEDVi vs PlexusDx: Which GLP-1 Program Is Better? (2026)
A detailed side-by-side comparison of MEDVi and PlexusDx to help you choose the right GLP-1 weight loss program based on pricing, medications, medical support, and more.
Quick Verdict
We recommend MEDVi
Between these two providers, MEDVi is our pick for most users. It offers a higher overall rating (8.9 vs 7.6), both brand-name and compounded medication options. That said, PlexusDx may be the better fit if you are looking for users who want one all-inclusive price that never changes with dose, and are curious about an optional genetic report.
MEDVi scores 8.9/10 in our evaluation at $299/month, while PlexusDx scores 7.6/10 at $149/month. Both programs include a licensed physician consultation and ship medication directly to your door. MEDVi also offers oral GLP-1 options for patients who prefer pills over injections. Our rating considers five factors: safety and medical oversight (30%), pricing transparency (25%), cost value (20%), clinical support quality (15%), and onboarding speed (10%). We earn affiliate commissions from some providers, disclosed on this page; no provider can pay to fake safety, licensing, or hide the downsides. Prices verified April 2026.
Side-by-Side Comparison
| Feature | MEDVi | PlexusDx |
|---|---|---|
| Monthly Price | $299 | $149 |
| Rating | 8.9 / 10 | 7.6 / 10 |
| Medication Type | Brand & Compounded | Compounded Only |
| Insurance Accepted | No | No |
| States Available | 49 states | All 50 states |
| Consultation Fee | Included | Included |
| Shipping | Free Shipping | Free Shipping |
| Cancel Anytime | Yes | Yes |
| Medical Support | Licensed physicians, unlimited visits, 24/7 messaging | US-licensed clinicians (LionMD network) via async intake, monthly check-ins and provider-reviewed refills; five states require a scheduled video consultation |
Prices reflect starting rates without insurance. Actual costs may vary by plan and medication. Last updated April 2026.
MEDVi: Detailed Look
MEDVi
Personalized GLP-1 with injectable and oral options — $179 first month, then $299
Pros
- Low $179 first-month price includes medication and consultation
- Both injectable and oral dissolving tablet options
- Unlimited doctor visits and 24/7 messaging support
- LegitScript certified for transparency and compliance
Cons
- Refill price jumps to $299/month after the first month
- Cash-pay only — no insurance accepted
- Received an FDA warning letter (Feb 2026) over website marketing claims on compounded GLP-1s — part of an industry-wide sweep of 30+ telehealth firms; concerned labeling/claims, not medication safety
Users who want a low entry price with oral and injectable compounded options
PlexusDx: Detailed Look
PlexusDx
All-inclusive compounded GLP-1 with flat pricing at every dose and an optional genetic test
Pros
- All-inclusive pricing with no membership fee: consult, prescription, medication, supplies and shipping in one monthly charge
- Flat price at every dose level, so the monthly cost does not rise as your dose is titrated up
- LegitScript certified (September 18, 2026), with its 503A compounding pharmacies named on the site
- Available in all 50 states, with injection, oral and low-dose microdose options
Cons
- Compounded medications are not FDA-approved
- Month-to-month pricing ($189 semaglutide, $289 tirzepatide) is well above the cheapest programs; the lower rates need a 3- or 6-month commitment
- No published refund policy, and the genetic test is an extra $99 that does not decide which medication you get
Users who want one all-inclusive price that never changes with dose, and are curious about an optional genetic report
Which Should You Choose?
The right choice depends on your specific needs and priorities. Here is a quick decision framework:
Go with PlexusDx at $149/month. Compounded semaglutide injections $189/mo month-to-month, $169/mo on the 3-month plan and $149/mo on the 6-month plan; compounded tirzepatide injections $289 / $269 / $249. Oral semaglutide runs $289 / $269 / $249 and oral tirzepatide $349 / $299 / $279; a low-dose Microdose GLP-1 program is $129/mo. Each price is all-inclusive (provider consult, prescription, medication, supplies and shipping), stays the same at every dose level, and carries no membership fee; nothing is charged until a provider approves the prescription. The site does not say whether the 3- and 6-month tiers are billed up front. An optional GLP-1 & Peptide Pathways genetic test is offered for $99 (list $298) after the first program order. Verified October 3, 2026..
MEDVi has the edge with a 8.9 rating.
PlexusDx focuses on compounded medications at a lower price point.
Compare their support: MEDVi offers licensed physicians, unlimited visits, 24/7 messaging, while PlexusDx provides us-licensed clinicians (lionmd network) via async intake, monthly check-ins and provider-reviewed refills; five states require a scheduled video consultation.
MEDVi at $299/month may offer features that justify the premium.
Frequently Asked Questions
Is MEDVi better than PlexusDx?
MEDVi has a 8.9 rating while PlexusDx has a 7.6 rating. The better choice depends on your priorities — MEDVi is best for users who want a low entry price with oral and injectable compounded options, while PlexusDx is best for users who want one all-inclusive price that never changes with dose, and are curious about an optional genetic report.
How much does MEDVi cost compared to PlexusDx?
MEDVi starts at $299/month ($179 first month with no contract, refills locked in at $299/mo — 'no membership or hidden fees, everything you need is included' on compounded glp-1 injections (tablets from $249). brand wegovy pill/injection and zepbound are priced as a $99 membership plus the medication cost. standing (refill) price $299 is what we rank on; the $179 first month is a promo (a 'summer sale!' banner on september 26). re-verified on glp1.medvi.org september 26, 2026.), while PlexusDx starts at $149/month (compounded semaglutide injections $189/mo month-to-month, $169/mo on the 3-month plan and $149/mo on the 6-month plan; compounded tirzepatide injections $289 / $269 / $249. oral semaglutide runs $289 / $269 / $249 and oral tirzepatide $349 / $299 / $279; a low-dose microdose glp-1 program is $129/mo. each price is all-inclusive (provider consult, prescription, medication, supplies and shipping), stays the same at every dose level, and carries no membership fee; nothing is charged until a provider approves the prescription. the site does not say whether the 3- and 6-month tiers are billed up front. an optional glp-1 & peptide pathways genetic test is offered for $99 (list $298) after the first program order. verified october 3, 2026.).
Do MEDVi and PlexusDx accept insurance?
MEDVi does not accept insurance. PlexusDx does not accept insurance.
Which GLP-1 medications does MEDVi offer vs PlexusDx?
MEDVi offers Compounded Semaglutide (Injectable), Compounded Semaglutide (Oral), Brand Wegovy / Zepbound ($99 membership + medication). PlexusDx offers Compounded Semaglutide, Compounded Semaglutide (oral), Compounded Tirzepatide, Compounded Tirzepatide (oral), Microdose GLP-1.
Can I cancel MEDVi or PlexusDx at any time?
MEDVi allows cancel anytime. PlexusDx also allows cancel anytime.
Are MEDVi and PlexusDx available in my state?
MEDVi is available in 49 states. PlexusDx is available in all 50 states.
Not sure MEDVi or PlexusDx is right for you?
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