SynergyRx vs MEDGm: Which GLP-1 Program Is Better? (2026)
A detailed side-by-side comparison of SynergyRx and MEDGm to help you choose the right GLP-1 weight loss program based on pricing, medications, medical support, and more.
Quick Verdict
We recommend MEDGm
Between these two providers, MEDGm is our pick for most users. It offers a higher overall rating (7.8 vs 5.6), more affordable pricing. That said, SynergyRx may be the better fit if you are looking for users who want predictable bundled pricing with 24/7 support access.
MEDGm scores 7.8/10 in our independent evaluation at $169/month, while SynergyRx scores 5.6/10 at $200/month. Both programs include a licensed physician consultation and ship medication directly to your door. MEDGm also offers oral GLP-1 options for patients who prefer pills over injections. Our rating considers five factors: safety and medical oversight (30%), pricing transparency (25%), cost value (20%), clinical support quality (15%), and onboarding speed (10%). We earn affiliate commissions from some providers, disclosed on this page; no provider can pay to fake safety, licensing, or hide the downsides. Prices verified April 2026.
Side-by-Side Comparison
| Feature | SynergyRx | MEDGm |
|---|---|---|
| Monthly Price | $200 | $169 |
| Rating | 5.6 / 10 | 7.8 / 10 |
| Medication Type | Brand & Compounded | Brand & Compounded |
| Insurance Accepted | No | No |
| States Available | 45 states | 49 states |
| Consultation Fee | Included | Included |
| Shipping | Free Shipping | Free Shipping |
| Cancel Anytime | Yes | Yes |
| Medical Support | Licensed providers, 24/7 messaging, unlimited check-ins | US-licensed clinicians via OpenLoop Health; provider-led plans and coaching; some states require a live video or phone consultation before prescribing |
Prices reflect starting rates without insurance. Actual costs may vary by plan and medication. Last updated April 2026.
SynergyRx: Detailed Look
SynergyRx
Bundled GLP-1 programs with 24/7 support and no hidden fees
Pros
- All-inclusive bundled pricing — no fees for messaging or adjustments
- Free expedited shipping on all orders
- 24/7 support access with unlimited messaging
- Partners with multiple certified pharmacies for reliability
Cons
- Starting price of $200/mo is mid-range for compounded semaglutide
- May not be available in all 50 states
Users who want predictable bundled pricing with 24/7 support access
MEDGm: Detailed Look
MEDGm
All-inclusive compounded GLP-1 program from $169/mo, with Wegovy and Zepbound pathways
Pros
- All-inclusive pricing: the $169 program price covers the clinical consultation, a metabolic report, the medication and expedited shipping
- 100% refund if the licensed clinician determines you don't qualify
- US-licensed clinicians via the OpenLoop Health network; medications from state-licensed 503A or FDA-registered 503B pharmacies, disclosed in its Terms
- LegitScript-certified site with brand Wegovy, Zepbound and Ozempic pathways and a dissolvable-tablet option
Cons
- Compounded medications are not FDA-approved
- Prepaid 3-, 6- and 12-month bundles are non-refundable once you are approved; cancellation needs 72 hours' notice before the next billing date
- The standing month-to-month rate and the tirzepatide price are only shown after the intake quiz; not available in Louisiana
Users who want one all-inclusive price, a refund if they aren't prescribed, and a brand-name fallback under the same roof
Which Should You Choose?
The right choice depends on your specific needs and priorities. Here is a quick decision framework:
Go with MEDGm at $169/month. Compounded GLP-1 injections 'starting at $169' per month, all-inclusive (clinical consultation, metabolic report, medication and expedited shipping); compounded GLP-1 tablets from $239. Plans are monthly or prepaid 3-, 6- or 12-month bundles, and the site does not say which term the $169 headline applies to or show the tirzepatide price before intake, so no standing per-molecule rate is recorded. Brand pathway: Wegovy (pill or pen) and Zepbound at a $99 membership plus the medication cost; Ozempic at $171 plus medication. HSA/FSA accepted. Verified September 23, 2026..
MEDGm has the edge with a 7.8 rating.
Compare their support: SynergyRx offers licensed providers, 24/7 messaging, unlimited check-ins, while MEDGm provides us-licensed clinicians via openloop health; provider-led plans and coaching; some states require a live video or phone consultation before prescribing.
SynergyRx at $200/month may offer features that justify the premium.
Frequently Asked Questions
Is SynergyRx better than MEDGm?
SynergyRx has a 5.6 rating while MEDGm has a 7.8 rating. The better choice depends on your priorities — SynergyRx is best for users who want predictable bundled pricing with 24/7 support access, while MEDGm is best for users who want one all-inclusive price, a refund if they aren't prescribed, and a brand-name fallback under the same roof.
How much does SynergyRx cost compared to MEDGm?
SynergyRx starts at $200/month ($200/mo semaglutide, $299-347/mo tirzepatide), while MEDGm starts at $169/month (compounded glp-1 injections 'starting at $169' per month, all-inclusive (clinical consultation, metabolic report, medication and expedited shipping); compounded glp-1 tablets from $239. plans are monthly or prepaid 3-, 6- or 12-month bundles, and the site does not say which term the $169 headline applies to or show the tirzepatide price before intake, so no standing per-molecule rate is recorded. brand pathway: wegovy (pill or pen) and zepbound at a $99 membership plus the medication cost; ozempic at $171 plus medication. hsa/fsa accepted. verified september 23, 2026.).
Do SynergyRx and MEDGm accept insurance?
SynergyRx does not accept insurance. MEDGm does not accept insurance.
Which GLP-1 medications does SynergyRx offer vs MEDGm?
SynergyRx offers Compounded Semaglutide, Compounded Tirzepatide, Ozempic, Wegovy, Mounjaro. MEDGm offers Compounded Semaglutide, Compounded Semaglutide (oral tablets), Compounded Tirzepatide, Wegovy, Zepbound, Ozempic.
Can I cancel SynergyRx or MEDGm at any time?
SynergyRx allows cancel anytime. MEDGm also allows cancel anytime.
Are SynergyRx and MEDGm available in my state?
SynergyRx is available in 45 states. MEDGm is available in 49 states.
Not sure SynergyRx or MEDGm is right for you?
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