MEDGm vs PlexusDx: Which GLP-1 Program Is Better? (2026)
A detailed side-by-side comparison of MEDGm and PlexusDx to help you choose the right GLP-1 weight loss program based on pricing, medications, medical support, and more.
Quick Verdict
We recommend MEDGm
Between these two providers, MEDGm is our pick for most users. It offers a higher overall rating (7.8 vs 7.6), both brand-name and compounded medication options. That said, PlexusDx may be the better fit if you are looking for users who want one all-inclusive price that never changes with dose, and are curious about an optional genetic report.
MEDGm scores 7.8/10 in our evaluation at $169/month, while PlexusDx scores 7.6/10 at $149/month. Both programs include a licensed physician consultation and ship medication directly to your door. MEDGm also offers oral GLP-1 options for patients who prefer pills over injections. Our rating considers five factors: safety and medical oversight (30%), pricing transparency (25%), cost value (20%), clinical support quality (15%), and onboarding speed (10%). We earn affiliate commissions from some providers, disclosed on this page; no provider can pay to fake safety, licensing, or hide the downsides. Prices verified April 2026.
Side-by-Side Comparison
| Feature | MEDGm | PlexusDx |
|---|---|---|
| Monthly Price | $169 | $149 |
| Rating | 7.8 / 10 | 7.6 / 10 |
| Medication Type | Brand & Compounded | Compounded Only |
| Insurance Accepted | No | No |
| States Available | 49 states | All 50 states |
| Consultation Fee | Included | Included |
| Shipping | Free Shipping | Free Shipping |
| Cancel Anytime | Yes | Yes |
| Medical Support | US-licensed clinicians via OpenLoop Health; provider-led plans and coaching; some states require a live video or phone consultation before prescribing | US-licensed clinicians (LionMD network) via async intake, monthly check-ins and provider-reviewed refills; five states require a scheduled video consultation |
Prices reflect starting rates without insurance. Actual costs may vary by plan and medication. Last updated April 2026.
MEDGm: Detailed Look
MEDGm
All-inclusive compounded GLP-1 program from $169/mo, with Wegovy and Zepbound pathways
Pros
- All-inclusive pricing: the $169 program price covers the clinical consultation, a metabolic report, the medication and expedited shipping
- 100% refund if the licensed clinician determines you don't qualify
- US-licensed clinicians via the OpenLoop Health network; medications from state-licensed 503A or FDA-registered 503B pharmacies, disclosed in its Terms
- LegitScript-certified site with brand Wegovy, Zepbound and Ozempic pathways and a dissolvable-tablet option
Cons
- Compounded medications are not FDA-approved
- Prepaid 3-, 6- and 12-month bundles are non-refundable once you are approved; cancellation needs 72 hours' notice before the next billing date
- The standing month-to-month rate and the tirzepatide price are only shown after the intake quiz; not available in Louisiana
Users who want one all-inclusive price, a refund if they aren't prescribed, and a brand-name fallback under the same roof
PlexusDx: Detailed Look
PlexusDx
All-inclusive compounded GLP-1 with flat pricing at every dose and an optional genetic test
Pros
- All-inclusive pricing with no membership fee: consult, prescription, medication, supplies and shipping in one monthly charge
- Flat price at every dose level, so the monthly cost does not rise as your dose is titrated up
- LegitScript certified (September 18, 2026), with its 503A compounding pharmacies named on the site
- Available in all 50 states, with injection, oral and low-dose microdose options
Cons
- Compounded medications are not FDA-approved
- Month-to-month pricing ($189 semaglutide, $289 tirzepatide) is well above the cheapest programs; the lower rates need a 3- or 6-month commitment
- No published refund policy, and the genetic test is an extra $99 that does not decide which medication you get
Users who want one all-inclusive price that never changes with dose, and are curious about an optional genetic report
Which Should You Choose?
The right choice depends on your specific needs and priorities. Here is a quick decision framework:
Go with PlexusDx at $149/month. Compounded semaglutide injections $189/mo month-to-month, $169/mo on the 3-month plan and $149/mo on the 6-month plan; compounded tirzepatide injections $289 / $269 / $249. Oral semaglutide runs $289 / $269 / $249 and oral tirzepatide $349 / $299 / $279; a low-dose Microdose GLP-1 program is $129/mo. Each price is all-inclusive (provider consult, prescription, medication, supplies and shipping), stays the same at every dose level, and carries no membership fee; nothing is charged until a provider approves the prescription. The site does not say whether the 3- and 6-month tiers are billed up front. An optional GLP-1 & Peptide Pathways genetic test is offered for $99 (list $298) after the first program order. Verified October 3, 2026..
MEDGm has the edge with a 7.8 rating.
PlexusDx focuses on compounded medications at a lower price point.
Compare their support: MEDGm offers us-licensed clinicians via openloop health; provider-led plans and coaching; some states require a live video or phone consultation before prescribing, while PlexusDx provides us-licensed clinicians (lionmd network) via async intake, monthly check-ins and provider-reviewed refills; five states require a scheduled video consultation.
MEDGm at $169/month may offer features that justify the premium.
Frequently Asked Questions
Is MEDGm better than PlexusDx?
MEDGm has a 7.8 rating while PlexusDx has a 7.6 rating. The better choice depends on your priorities — MEDGm is best for users who want one all-inclusive price, a refund if they aren't prescribed, and a brand-name fallback under the same roof, while PlexusDx is best for users who want one all-inclusive price that never changes with dose, and are curious about an optional genetic report.
How much does MEDGm cost compared to PlexusDx?
MEDGm starts at $169/month (compounded glp-1 injections 'starting at $169' per month, all-inclusive (clinical consultation, metabolic report, medication and expedited shipping); compounded glp-1 tablets from $239. plans are monthly or prepaid 3-, 6- or 12-month bundles, and the site does not say which term the $169 headline applies to or show the tirzepatide price before intake, so no standing per-molecule rate is recorded. brand pathway: wegovy (pill or pen) and zepbound at a $99 membership plus the medication cost; ozempic at $171 plus medication. hsa/fsa accepted. verified september 23, 2026.), while PlexusDx starts at $149/month (compounded semaglutide injections $189/mo month-to-month, $169/mo on the 3-month plan and $149/mo on the 6-month plan; compounded tirzepatide injections $289 / $269 / $249. oral semaglutide runs $289 / $269 / $249 and oral tirzepatide $349 / $299 / $279; a low-dose microdose glp-1 program is $129/mo. each price is all-inclusive (provider consult, prescription, medication, supplies and shipping), stays the same at every dose level, and carries no membership fee; nothing is charged until a provider approves the prescription. the site does not say whether the 3- and 6-month tiers are billed up front. an optional glp-1 & peptide pathways genetic test is offered for $99 (list $298) after the first program order. verified october 3, 2026.).
Do MEDGm and PlexusDx accept insurance?
MEDGm does not accept insurance. PlexusDx does not accept insurance.
Which GLP-1 medications does MEDGm offer vs PlexusDx?
MEDGm offers Compounded Semaglutide, Compounded Semaglutide (oral tablets), Compounded Tirzepatide, Wegovy, Zepbound, Ozempic. PlexusDx offers Compounded Semaglutide, Compounded Semaglutide (oral), Compounded Tirzepatide, Compounded Tirzepatide (oral), Microdose GLP-1.
Can I cancel MEDGm or PlexusDx at any time?
MEDGm allows cancel anytime. PlexusDx also allows cancel anytime.
Are MEDGm and PlexusDx available in my state?
MEDGm is available in 49 states. PlexusDx is available in all 50 states.
Not sure MEDGm or PlexusDx is right for you?
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