MangoRx vs SynergyRx
Recorded prices, access and terms.
The short answer
- Cheapest to start, semaglutide: Neither has a recorded semaglutide monthly-plan rate. The sellers' own lines read MangoRx: "$299/mo, oral tablet". Those terms differ, so we do not rank them.
- Cheapest to start, tirzepatide: Neither has a tirzepatide monthly-plan rate on our record. Price on seller's site.
- Cheapest over 12 months, semaglutide: Neither record holds a rate and term we can carry to 12 months for semaglutide.
- Cheapest over 12 months, tirzepatide: Neither record holds a rate and term we can carry to 12 months for tirzepatide.
- Broadest availability: Both are recorded in 45 states.
- Drugs: MangoRx lists compounded medication only; SynergyRx lists brand-name and compounded medication.
Price lines compare recorded monthly-plan subtotals and term totals, as on our price pages. A lower recorded rate is not a complete cost: labs, dose changes and the amount due today can differ.
Decision table
The entries below are recorded provider statements unless a regulatory source is linked. A provider webpage does not independently verify its licenses or quality. MangoRx source · SynergyRx source.
| Compare | MangoRx | SynergyRx |
|---|---|---|
| Recorded monthly-plan price | Not recorded | Not recorded |
| Recorded medication/program subtotal | Seller's headline: $299/mo oral semaglutide tablet. It may require prepayment, a specific dose or introductory terms. The full required cost is not established. | No monthly-plan rate is recorded. See the seller's site for current prices. The full required cost is not established. |
| Lowest 12-month total on the record | No rate and term we can carry to 12 months | No rate and term we can carry to 12 months |
| Full required monthly cost | Not established: consultation, labs, membership, dose changes and shipping must be checked | Not established: consultation, labs, membership, dose changes and shipping must be checked |
| Drug type listed | Compounded | Brand-name and compounded |
| Oral option | Injections only on the record | Injections only on the record |
| Consultation | Free in the record; current conditions unconfirmed | Included in the record; current conditions unconfirmed |
| Membership or program fee | Not separately recorded; do not assume zero. | Not separately recorded; do not assume zero. |
| Shipping | Recorded as included; confirm for your address | Recorded as included; confirm for your address |
| Labs | Required tests and any lab charge are not recorded. | Required tests and any lab charge are not recorded. |
| Insurance | Self-pay on the record | Self-pay on the record |
| Pharmacy license | Not independently verified. Obtain the dispensing pharmacy name and verify its state license. | Not independently verified. Obtain the dispensing pharmacy name and verify its state license. |
| Reported states | 45; confirm eligibility and clinician licensing in your state | 45; confirm eligibility and clinician licensing in your state |
| Cancellation | Cancellation reported; notice, minimum term and refund conditions unconfirmed | Cancellation reported; notice, minimum term and refund conditions unconfirmed |
| Clinician/support as reported | Licensed U.S. physicians, ongoing support | Licensed providers, 24/7 messaging, unlimited check-ins |
| Trustpilot | 4.4/5 from 18 reviews (read Nov 5, 2026) | No Trustpilot profile we could quote |
| Recorded provider check | 2026-11-06 | No date recorded |
Price by plan and term
Each rate is a per-month amount for the plan named, from the seller's own page on the date shown. A term plan's rate needs the full term; the total under it is the rate times the months.
MangoRx
| Plan or term | Semaglutide | Tirzepatide | Source and read date |
|---|---|---|---|
| Seller's headline | $299/mo, oral tablet | Not listed | MangoRx page, read Nov 6, 2026 |
Oral only: MangoRx's 'Slim' is a compounded semaglutide + vitamin B6 orally dissolving tablet at $299 for a 30-day supply, billed month-to-month with the price locked in; provider visits and shipping are free. MangoRx does not sell injectable semaglutide or tirzepatide, so it is not in our injectable price ladders. Read September 2, 2026 on mangorx.com/products/slim.
SynergyRx
No plan rate or seller headline is on our record. See SynergyRx's site for current prices.
On November 6, 2026 synergyrx.com pointed to a domain-parking service and redirected to a domain sale listing on sedo.com, with no provider site shown. These prices are from an earlier record and could not be re-read: $200/mo semaglutide, $299-347/mo tirzepatide.
What is included
MangoRx
Visits: consultation recorded as "Free". Care: Licensed U.S. physicians, ongoing support.
Shipping: recorded as included.
Labs: Required tests and any lab charge are not recorded.
Dose increases: A price for each dose step is not recorded.
What MangoRx lists:
- Multi-service platform: weight loss, ED, hair loss, skincare
- Free shipping on all orders
- Simple online intake with no appointment needed
How it works, per MangoRx's page:
- Complete a medical questionnaire and consult a licensed provider.
- The provider reviews your history and may prescribe the Slim oral semaglutide tablet.
- Tablets ship to your door monthly.
SynergyRx
Visits: consultation recorded as "Included". Care: Licensed providers, 24/7 messaging, unlimited check-ins.
Shipping: recorded as included.
Labs: Required tests and any lab charge are not recorded.
Dose increases: A price for each dose step is not recorded.
What SynergyRx lists:
- Free expedited shipping on all orders
- 24/7 support access with unlimited messaging
- Partners with multiple certified pharmacies for reliability
States served
MangoRx: 45 states
Recorded as available in 45 states.
The record names no excluded state. Confirm yours at intake.
SynergyRx: 45 states
Recorded as available in 45 states.
- May not be available in all 50 states
State-by-state costs and Medicaid notes are on the GLP-1 cost by state pages.
Drugs offered
MangoRx: compounded medication only
- Compounded Semaglutide
- Compounded Tirzepatide
Injections only on the record.
SynergyRx: brand-name and compounded medication
- Compounded Semaglutide
- Compounded Tirzepatide
- Ozempic
- Wegovy
- Mounjaro
Injections only on the record.
Compounded drugs are made by a pharmacy for a patient and are not the brand products. Compounded vs brand-name GLP-1.
Membership and other fees
- MangoRx: Not separately recorded; do not assume zero.
- SynergyRx: Not separately recorded; do not assume zero.
A fee missing from the record is unknown, not zero.
Cancellation and refunds
MangoRx
Recorded as cancel anytime; notice deadlines, prepaid-plan limits and refund rights are not fully recorded.
SynergyRx
Recorded as cancel anytime; notice deadlines, prepaid-plan limits and refund rights are not fully recorded.
Which should you choose?
MangoRx
On price, states and drug type the record does not put MangoRx ahead of SynergyRx. It suits a reader who prefers its care model: licensed u.s. physicians, ongoing support.
SynergyRx
On the record, SynergyRx suits a reader who wants brand-name, FDA-approved medication.
Ask each provider for the full cost at your prescribed dose, required labs and visits, the dispensing pharmacy, the clinician's state license, renewal charges and written refund terms. Compare those answers with your clinician.
Compounded drugs are not FDA-approved and do not undergo FDA review for safety, effectiveness or quality before marketing. FDA source and recommendations.
MangoRx: evidence and terms
SynergyRx: evidence and terms
MangoRx vs SynergyRx: questions
Which is cheaper, MangoRx or SynergyRx?
Neither has a recorded semaglutide monthly-plan rate. The sellers' own lines read MangoRx: "$299/mo, oral tablet". Those terms differ, so we do not rank them. Neither has a tirzepatide monthly-plan rate on our record. Price on seller's site. These are medication and recorded program-fee subtotals; labs, dose changes and other charges may be extra.
Which costs less over a year, MangoRx or SynergyRx?
Neither record holds a rate and term we can carry to 12 months for semaglutide. Neither record holds a rate and term we can carry to 12 months for tirzepatide. A term plan commits you for the full term, so check its refund rules first.
Is MangoRx or SynergyRx available in more states?
Both are recorded in 45 states. SynergyRx: May not be available in all 50 states. Confirm your state at intake.
Do MangoRx and SynergyRx offer brand-name or compounded GLP-1?
MangoRx lists compounded medication only (Compounded Semaglutide, Compounded Tirzepatide). SynergyRx lists brand-name and compounded medication (Compounded Semaglutide, Compounded Tirzepatide, Ozempic, Wegovy, Mounjaro). Compounded drugs are not FDA-approved.
Does MangoRx or SynergyRx charge a membership fee?
MangoRx: Not separately recorded; do not assume zero. SynergyRx: Not separately recorded; do not assume zero.
Can you cancel MangoRx or SynergyRx at any time?
MangoRx: Recorded as cancel anytime; notice deadlines, prepaid-plan limits and refund rights are not fully recorded. SynergyRx: Recorded as cancel anytime; notice deadlines, prepaid-plan limits and refund rights are not fully recorded.
Are the visit and shipping included with MangoRx and SynergyRx?
MangoRx: consultation recorded as "Free", shipping recorded as included. SynergyRx: consultation recorded as "Included", shipping recorded as included.
Do MangoRx or SynergyRx take insurance?
Neither is recorded as accepting insurance; both are self-pay on our record.
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