ShedRx vs MangoRx: Which GLP-1 Program Is Better? (2026)
A detailed side-by-side comparison of ShedRx and MangoRx to help you choose the right GLP-1 weight loss program based on pricing, medications, medical support, and more.
Quick Verdict
We recommend ShedRx
Between these two providers, ShedRx is our pick for most users. It offers a higher overall rating (8.8 vs 7.5), more affordable pricing, availability in all 50 states, both brand-name and compounded medication options. That said, MangoRx may be the better fit if you are looking for users who want a multi-service telehealth platform covering weight loss and men's health.
ShedRx scores 8.8/10 in our evaluation at $159/month, while MangoRx scores 7.5/10 at $299/month. Both programs include a licensed physician consultation and ship medication directly to your door. ShedRx also offers oral GLP-1 options for patients who prefer pills over injections. Our rating considers five factors: safety and medical oversight (30%), pricing transparency (25%), cost value (20%), clinical support quality (15%), and onboarding speed (10%). We earn affiliate commissions from some providers, disclosed on this page; no provider can pay to fake safety, licensing, or hide the downsides. Prices verified April 2026.
Side-by-Side Comparison
| Feature | ShedRx | MangoRx |
|---|---|---|
| Monthly Price | $159 | $299 |
| Rating | 8.8 / 10 | 7.5 / 10 |
| Medication Type | Brand & Compounded | Compounded Only |
| Insurance Accepted | No | No |
| States Available | All 50 states | 45 states |
| Consultation Fee | Included | Free |
| Shipping | Free Shipping | Free Shipping |
| Cancel Anytime | No | Yes |
| Medical Support | Licensed physicians, health coaching, supplement guidance | Licensed U.S. physicians, ongoing support |
Prices reflect starting rates without insurance. Actual costs may vary by plan and medication. Last updated April 2026.
ShedRx: Detailed Look
ShedRx
150K+ members with 5 medication forms — injections, oral drops, lozenges, tablets, and pills
Pros
- Most delivery forms of any provider: injections, oral drops, lozenges, tablets, and pills
- 120-day guarantee: lose 5% (or reach your goal weight) or your money back — first-time GLP-1 users, coaching and check-in conditions apply
- Both compounded and brand-name options (Wegovy, Zepbound)
- 150,000+ members, health coaching and supplements included
Cons
- 2-month minimum on every plan; the $159 rate needs a 12-month commitment ($199 month-to-month)
- Recurring Trustpilot complaints about cancellations, reaching support and unexpected charges
Users who want multiple medication delivery forms and a money-back weight loss guarantee
MangoRx: Detailed Look
MangoRx
Telehealth platform for weight loss, men's health, and wellness
Pros
- Multi-service platform — weight loss, ED, hair loss, skincare
- Licensed U.S. physicians prescribe all medications
- Free shipping on all orders
- Simple online intake with no appointment needed
Cons
- Pricing details require completing intake form
- Compounded medications only — no brand-name options
Users who want a multi-service telehealth platform covering weight loss and men's health
Which Should You Choose?
The right choice depends on your specific needs and priorities. Here is a quick decision framework:
Go with ShedRx at $159/month. Now trading as Shed (tryshed.com). Compounded semaglutide from $159/mo (12-month plan; $179 6-month, $199 monthly) and tirzepatide from $239/mo ($269 / $299). Oral options: lozenges from $199, liquid drops from $229, semaglutide tablets from $299. Brand pathway: Wegovy pill $149 / pen $199, Zepbound $349, Foundayo $149 — medication only, plus a $125/mo Shed membership. Every plan carries a 2-month minimum..
ShedRx has the edge with a 8.8 rating.
MangoRx focuses on compounded medications at a lower price point.
Compare their support: ShedRx offers licensed physicians, health coaching, supplement guidance, while MangoRx provides licensed u.s. physicians, ongoing support.
MangoRx at $299/month may offer features that justify the premium.
Frequently Asked Questions
Is ShedRx better than MangoRx?
ShedRx has a 8.8 rating while MangoRx has a 7.5 rating. The better choice depends on your priorities — ShedRx is best for users who want multiple medication delivery forms and a money-back weight loss guarantee, while MangoRx is best for users who want a multi-service telehealth platform covering weight loss and men's health.
How much does ShedRx cost compared to MangoRx?
ShedRx starts at $159/month (now trading as shed (tryshed.com). compounded semaglutide from $159/mo (12-month plan; $179 6-month, $199 monthly) and tirzepatide from $239/mo ($269 / $299). oral options: lozenges from $199, liquid drops from $229, semaglutide tablets from $299. brand pathway: wegovy pill $149 / pen $199, zepbound $349, foundayo $149 — medication only, plus a $125/mo shed membership. every plan carries a 2-month minimum.), while MangoRx starts at $299/month (oral only: mangorx's 'slim' is a compounded semaglutide + vitamin b6 orally dissolving tablet at $299 for a 30-day supply, billed month-to-month with the price locked in; provider visits and shipping are free. mangorx does not sell injectable semaglutide or tirzepatide, so it is not in our injectable price ladders. verified september 2, 2026 on mangorx.com/products/slim.).
Do ShedRx and MangoRx accept insurance?
ShedRx does not accept insurance. MangoRx does not accept insurance.
Which GLP-1 medications does ShedRx offer vs MangoRx?
ShedRx offers Compounded Semaglutide, Compounded Tirzepatide, Wegovy, Zepbound, Foundayo (oral orforglipron). MangoRx offers Compounded Semaglutide, Compounded Tirzepatide.
Can I cancel ShedRx or MangoRx at any time?
ShedRx may have cancellation restrictions. MangoRx also allows cancel anytime.
Are ShedRx and MangoRx available in my state?
ShedRx is available in all 50 states. MangoRx is available in 45 states.
Not sure ShedRx or MangoRx is right for you?
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