MangoRx vs Sesame Care: Which GLP-1 Program Is Better? (2026)
A detailed side-by-side comparison of MangoRx and Sesame Care to help you choose the right GLP-1 weight loss program based on pricing, medications, medical support, and more.
Quick Verdict
We recommend MangoRx
Between these two providers, MangoRx is our pick for most users. It offers a higher overall rating (7.5 vs 7.2), more affordable pricing. That said, Sesame Care may be the better fit if you are looking for users with insurance who want cheap doctor visits — medication costs are separate and not included.
MangoRx scores 7.5/10 in our independent evaluation at $195/month, while Sesame Care scores 7.2/10 at $225/month. Both programs include a licensed physician consultation and ship medication directly to your door. Our rating considers five factors: safety and medical oversight (30%), pricing transparency (25%), cost value (20%), clinical support quality (15%), and onboarding speed (10%). We earn affiliate commissions from some providers, disclosed on this page; no provider can pay to fake safety, licensing, or hide the downsides. Prices verified April 2026.
Side-by-Side Comparison
| Feature | MangoRx | Sesame Care |
|---|---|---|
| Monthly Price | $195 | $225 |
| Rating | 7.5 / 10 | 7.2 / 10 |
| Medication Type | Compounded Only | Brand & Compounded |
| Insurance Accepted | No | Yes |
| States Available | 45 states | All 50 states |
| Consultation Fee | Free | $25-75 |
| Shipping | Free Shipping | Paid |
| Cancel Anytime | Yes | Yes |
| Medical Support | Licensed U.S. physicians, ongoing support | Licensed physicians, per-visit model |
Prices reflect starting rates without insurance. Actual costs may vary by plan and medication. Last updated April 2026.
MangoRx: Detailed Look
MangoRx
Telehealth platform for weight loss, men's health, and wellness
Pros
- Multi-service platform — weight loss, ED, hair loss, skincare
- Licensed U.S. physicians prescribe all medications
- Free shipping on all orders
- Simple online intake with no appointment needed
Cons
- Pricing details require completing intake form
- Compounded medications only — no brand-name options
Users who want a multi-service telehealth platform covering weight loss and men's health
Sesame Care: Detailed Look
Sesame Care
Affordable telehealth marketplace connecting patients with doctors from $25
Pros
- Lowest consultation cost — visits from just $25
- Prescribes brand-name FDA-approved medications
- Transparent per-visit pricing with no subscriptions
- Wide network of licensed physicians across all 50 states
Cons
- Medication cost is separate and not included in visit fee
- No compounded options — brand-name only (higher drug cost)
Users with insurance who want cheap doctor visits — medication costs are separate and not included
Which Should You Choose?
The right choice depends on your specific needs and priorities. Here is a quick decision framework:
Go with MangoRx at $195/month. Estimated starting price for GLP-1 program.
MangoRx has the edge with a 7.5 rating.
Sesame Care accepts insurance, which can significantly reduce your out-of-pocket cost.
MangoRx focuses on compounded medications at a lower price point.
Compare their support: MangoRx offers licensed u.s. physicians, ongoing support, while Sesame Care provides licensed physicians, per-visit model.
Sesame Care at $225/month may offer features that justify the premium.
Frequently Asked Questions
Is MangoRx better than Sesame Care?
MangoRx has a 7.5 rating while Sesame Care has a 7.2 rating. The better choice depends on your priorities — MangoRx is best for users who want a multi-service telehealth platform covering weight loss and men's health, while Sesame Care is best for users with insurance who want cheap doctor visits — medication costs are separate and not included.
How much does MangoRx cost compared to Sesame Care?
MangoRx starts at $195/month (estimated starting price for glp-1 program), while Sesame Care starts at $225/month ($25-75 per visit + medication at pharmacy prices ($200-1,400/mo). total starting cost ~$225/mo with insurance savings cards. medication not included in visit fee.).
Do MangoRx and Sesame Care accept insurance?
MangoRx does not accept insurance. Sesame Care accepts insurance.
Which GLP-1 medications does MangoRx offer vs Sesame Care?
MangoRx offers Compounded Semaglutide, Compounded Tirzepatide. Sesame Care offers Ozempic, Wegovy, Mounjaro, Zepbound, Rybelsus.
Can I cancel MangoRx or Sesame Care at any time?
MangoRx allows cancel anytime. Sesame Care also allows cancel anytime.
Are MangoRx and Sesame Care available in my state?
MangoRx is available in 45 states. Sesame Care is available in all 50 states.
Not sure MangoRx or Sesame Care is right for you?
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