Sesame Care vs MangoRx: Which GLP-1 Program Is Better? (2026)
A detailed side-by-side comparison of Sesame Care and MangoRx to help you choose the right GLP-1 weight loss program based on pricing, medications, medical support, and more.
Quick Verdict
We recommend MangoRx
Between these two providers, MangoRx is our pick for most users. It offers a higher overall rating (7.5 vs 7.2). That said, Sesame Care may be the better fit if you are looking for people who specifically want brand-name fda-approved glp-1s and will commit to a year of care — not the cheapest route, and no compounded option.
MangoRx scores 7.5/10 in our independent evaluation at $299/month, while Sesame Care scores 7.2/10 at $208/month. Both programs include a licensed physician consultation and ship medication directly to your door. Our rating considers five factors: safety and medical oversight (30%), pricing transparency (25%), cost value (20%), clinical support quality (15%), and onboarding speed (10%). We earn affiliate commissions from some providers, disclosed on this page; no provider can pay to fake safety, licensing, or hide the downsides. Prices verified April 2026.
Side-by-Side Comparison
| Feature | Sesame Care | MangoRx |
|---|---|---|
| Monthly Price | $208 | $299 |
| Rating | 7.2 / 10 | 7.5 / 10 |
| Medication Type | Brand-Name Only | Compounded Only |
| Insurance Accepted | Yes | No |
| States Available | All 50 states | 45 states |
| Consultation Fee | $59/mo care subscription (12-month commitment) | Free |
| Shipping | Paid | Free Shipping |
| Cancel Anytime | Yes | Yes |
| Medical Support | Licensed physicians, per-visit model | Licensed U.S. physicians, ongoing support |
Prices reflect starting rates without insurance. Actual costs may vary by plan and medication. Last updated April 2026.
Sesame Care: Detailed Look
Sesame Care
Affordable telehealth marketplace connecting patients with doctors from $25
Pros
- Lowest consultation cost — visits from just $25
- Prescribes brand-name FDA-approved medications
- Transparent pricing: a $59/mo care subscription plus the manufacturer's own medication price
- Wide network of licensed physicians across all 50 states
Cons
- Medication cost is separate and not included in visit fee
- No compounded options — brand-name only (higher drug cost)
People who specifically want brand-name FDA-approved GLP-1s and will commit to a year of care — not the cheapest route, and no compounded option
MangoRx: Detailed Look
MangoRx
Telehealth platform for weight loss, men's health, and wellness
Pros
- Multi-service platform — weight loss, ED, hair loss, skincare
- Licensed U.S. physicians prescribe all medications
- Free shipping on all orders
- Simple online intake with no appointment needed
Cons
- Pricing details require completing intake form
- Compounded medications only — no brand-name options
Users who want a multi-service telehealth platform covering weight loss and men's health
Which Should You Choose?
The right choice depends on your specific needs and priorities. Here is a quick decision framework:
Go with Sesame Care at $208/month. Sesame has moved to a "Success by Sesame" subscription: $59/mo for care (priced on a 12-month commitment) plus medication billed separately — Wegovy from $149/mo brings the all-in to roughly $208/mo, and Zepbound from $299/mo to roughly $358/mo. Brand-name FDA-approved medication only; Sesame no longer offers a compounded option, so it does not appear in our compounded price ladders. Sesame notes medication pricing may vary by treatment, dose, pharmacy and provider, so these are floors rather than guarantees. Verified August 31, 2026..
MangoRx has the edge with a 7.5 rating.
Sesame Care accepts insurance, which can significantly reduce your out-of-pocket cost.
Choose Sesame Care which exclusively prescribes brand-name medications.
MangoRx focuses on compounded medications at a lower price point.
Compare their support: Sesame Care offers licensed physicians, per-visit model, while MangoRx provides licensed u.s. physicians, ongoing support.
MangoRx at $299/month may offer features that justify the premium.
Frequently Asked Questions
Is Sesame Care better than MangoRx?
Sesame Care has a 7.2 rating while MangoRx has a 7.5 rating. The better choice depends on your priorities — Sesame Care is best for people who specifically want brand-name fda-approved glp-1s and will commit to a year of care — not the cheapest route, and no compounded option, while MangoRx is best for users who want a multi-service telehealth platform covering weight loss and men's health.
How much does Sesame Care cost compared to MangoRx?
Sesame Care starts at $208/month (sesame has moved to a "success by sesame" subscription: $59/mo for care (priced on a 12-month commitment) plus medication billed separately — wegovy from $149/mo brings the all-in to roughly $208/mo, and zepbound from $299/mo to roughly $358/mo. brand-name fda-approved medication only; sesame no longer offers a compounded option, so it does not appear in our compounded price ladders. sesame notes medication pricing may vary by treatment, dose, pharmacy and provider, so these are floors rather than guarantees. verified august 31, 2026.), while MangoRx starts at $299/month (oral only: mangorx's 'slim' is a compounded semaglutide + vitamin b6 orally dissolving tablet at $299 for a 30-day supply, billed month-to-month with the price locked in; provider visits and shipping are free. mangorx does not sell injectable semaglutide or tirzepatide, so it is not in our injectable price ladders. verified september 2, 2026 on mangorx.com/products/slim.).
Do Sesame Care and MangoRx accept insurance?
Sesame Care accepts insurance. MangoRx does not accept insurance.
Which GLP-1 medications does Sesame Care offer vs MangoRx?
Sesame Care offers Wegovy, Wegovy HD, Wegovy (oral), Zepbound, Zepbound KwikPen, Foundayo. MangoRx offers Compounded Semaglutide, Compounded Tirzepatide.
Can I cancel Sesame Care or MangoRx at any time?
Sesame Care allows cancel anytime. MangoRx also allows cancel anytime.
Are Sesame Care and MangoRx available in my state?
Sesame Care is available in all 50 states. MangoRx is available in 45 states.
Not sure Sesame Care or MangoRx is right for you?
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