SynergyRx vs Hers: Which GLP-1 Program Is Better? (2026)
A detailed side-by-side comparison of SynergyRx and Hers to help you choose the right GLP-1 weight loss program based on pricing, medications, medical support, and more.
Quick Verdict
We recommend Hers
Between these two providers, Hers is our pick for most users. It offers a higher overall rating (7.5 vs 5.6), more affordable pricing. That said, SynergyRx may be the better fit if you are looking for users who want predictable bundled pricing with 24/7 support access.
Hers scores 7.5/10 in our independent evaluation at $149/month, while SynergyRx scores 5.6/10 at $200/month. Both programs include a licensed physician consultation and ship medication directly to your door. Hers also offers oral GLP-1 options for patients who prefer pills over injections. Our rating considers five factors: safety and medical oversight (30%), pricing transparency (25%), cost value (20%), clinical support quality (15%), and onboarding speed (10%). We earn affiliate commissions from some providers, disclosed on this page; no provider can pay to fake safety, licensing, or hide the downsides. Prices verified April 2026.
Side-by-Side Comparison
| Feature | SynergyRx | Hers |
|---|---|---|
| Monthly Price | $200 | $149 |
| Rating | 5.6 / 10 | 7.5 / 10 |
| Medication Type | Brand & Compounded | Brand-Name Only |
| Insurance Accepted | No | No |
| States Available | 45 states | 45 states |
| Consultation Fee | Included | $0 |
| Shipping | Free Shipping | Free Shipping |
| Cancel Anytime | Yes | Yes |
| Medical Support | Licensed providers, 24/7 messaging, unlimited check-ins | Licensed healthcare providers via online consultation |
Prices reflect starting rates without insurance. Actual costs may vary by plan and medication. Last updated April 2026.
SynergyRx: Detailed Look
SynergyRx
Bundled GLP-1 programs with 24/7 support and no hidden fees
Pros
- All-inclusive bundled pricing — no fees for messaging or adjustments
- Free expedited shipping on all orders
- 24/7 support access with unlimited messaging
- Partners with multiple certified pharmacies for reliability
Cons
- Starting price of $200/mo is mid-range for compounded semaglutide
- May not be available in all 50 states
Users who want predictable bundled pricing with 24/7 support access
Hers: Detailed Look
Hers
Women-focused telehealth offering brand-name Wegovy and Zepbound
Pros
- Offers FDA-approved brand-name GLP-1s — Wegovy pen, oral Wegovy, and Zepbound
- Polished, women-focused app with free discreet shipping
- Both oral and injectable semaglutide options
- First month membership discounted to $39 to try the platform
Cons
- $149/mo membership sits on top of pricey brand medication — realistic all-in roughly $298–$448/mo
- Discontinued low-cost compounded semaglutide for new patients (March 2026 settlement)
- Cash-pay only — does not bill insurance
- Recurring billing and cancellation complaints in reviews
women who want brand-name Wegovy or Zepbound through a polished app and accept membership plus retail medication cost
Which Should You Choose?
The right choice depends on your specific needs and priorities. Here is a quick decision framework:
Go with Hers at $149/month. $149/mo membership ($39 first month) on top of brand-name medication billed separately, so realistic all-in cost runs roughly $298–$448/mo. Hers stopped selling compounded semaglutide to new patients after the March 2026 Novo Nordisk settlement, so the low-cost compounded option is gone. Cash-pay only..
Hers has the edge with a 7.5 rating.
Choose Hers which exclusively prescribes brand-name medications.
Compare their support: SynergyRx offers licensed providers, 24/7 messaging, unlimited check-ins, while Hers provides licensed healthcare providers via online consultation.
SynergyRx at $200/month may offer features that justify the premium.
Frequently Asked Questions
Is SynergyRx better than Hers?
SynergyRx has a 5.6 rating while Hers has a 7.5 rating. The better choice depends on your priorities — SynergyRx is best for users who want predictable bundled pricing with 24/7 support access, while Hers is best for women who want brand-name wegovy or zepbound through a polished app and accept membership plus retail medication cost.
How much does SynergyRx cost compared to Hers?
SynergyRx starts at $200/month ($200/mo semaglutide, $299-347/mo tirzepatide), while Hers starts at $149/month ($149/mo membership ($39 first month) on top of brand-name medication billed separately, so realistic all-in cost runs roughly $298–$448/mo. hers stopped selling compounded semaglutide to new patients after the march 2026 novo nordisk settlement, so the low-cost compounded option is gone. cash-pay only.).
Do SynergyRx and Hers accept insurance?
SynergyRx does not accept insurance. Hers does not accept insurance.
Which GLP-1 medications does SynergyRx offer vs Hers?
SynergyRx offers Compounded Semaglutide, Compounded Tirzepatide, Ozempic, Wegovy, Mounjaro. Hers offers Wegovy (injectable), Wegovy (oral), Zepbound, Ozempic.
Can I cancel SynergyRx or Hers at any time?
SynergyRx allows cancel anytime. Hers also allows cancel anytime.
Are SynergyRx and Hers available in my state?
SynergyRx is available in 45 states. Hers is available in 45 states.
Not sure SynergyRx or Hers is right for you?
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