HealthRX vs PlexusDx
Recorded prices, access and terms.
The short answer
- Cheapest to start, semaglutide: HealthRX is lower for semaglutide on the monthly plan: $125/mo against $189/mo at PlexusDx, a $64 gap.
- Cheapest to start, tirzepatide: HealthRX is lower for tirzepatide on the monthly plan: $201/mo against $289/mo at PlexusDx, a $88 gap.
- Cheapest over 12 months, semaglutide: Over 12 months HealthRX is lower for semaglutide: $1,164 on the 12-month plan, against $2,268 at PlexusDx on 12 months on the monthly plan.
- Cheapest over 12 months, tirzepatide: Over 12 months HealthRX is lower for tirzepatide: $2,124 on the 12-month plan, against $3,468 at PlexusDx on 12 months on the monthly plan.
- Broadest availability: Both are recorded in 50 states.
- Drugs: HealthRX lists compounded medication only; PlexusDx lists compounded medication only.
Price lines compare recorded monthly-plan subtotals and term totals, as on our price pages. A lower recorded rate is not a complete cost: labs, dose changes and the amount due today can differ.
Decision table
The entries below are recorded provider statements unless a regulatory source is linked. A provider webpage does not independently verify its licenses or quality. HealthRX source · PlexusDx source.
| Compare | HealthRX | PlexusDx |
|---|---|---|
| Recorded monthly-plan price | $125/mo semaglutide, $201/mo tirzepatide | $189/mo semaglutide, $289/mo tirzepatide |
| Recorded medication/program subtotal | Recorded medication and program subtotal: semaglutide: $125/month; tirzepatide: $201/month. Other required fees, labs, dose changes and renewal terms are not established. This is not a verified all-in treatment cost. | Recorded medication and program subtotal: semaglutide: $189/month; tirzepatide: $289/month. Other required fees, labs, dose changes and renewal terms are not established. This is not a verified all-in treatment cost. |
| Lowest 12-month total on the record | semaglutide $1,164 (the 12-month plan); tirzepatide $2,124 (the 12-month plan) | semaglutide $2,268 (12 months on the monthly plan); tirzepatide $3,468 (12 months on the monthly plan) |
| Full required monthly cost | Not established: consultation, labs, membership, dose changes and shipping must be checked | Not established: consultation, labs, membership, dose changes and shipping must be checked |
| Drug type listed | Compounded | Compounded |
| Oral option | Injections only on the record | Listed |
| Consultation | Included, per its pricing page in the record; current conditions unconfirmed | Included in the record; current conditions unconfirmed |
| Membership or program fee | Not separately recorded; do not assume zero. | Not separately recorded; do not assume zero. |
| Shipping | Recorded as included; confirm for your address | Recorded as included; confirm for your address |
| Labs | Required tests and any lab charge are not recorded. | Required tests and any lab charge are not recorded. |
| Insurance | Self-pay on the record | Self-pay on the record |
| Pharmacy license | Not independently verified. Obtain the dispensing pharmacy name and verify its state license. | Not independently verified. Obtain the dispensing pharmacy name and verify its state license. |
| Reported states | 50; confirm eligibility and clinician licensing in your state | 50; confirm eligibility and clinician licensing in your state |
| Cancellation | Cancellation reported; notice, minimum term and refund conditions unconfirmed | Cancellation reported; notice, minimum term and refund conditions unconfirmed |
| Clinician/support as reported | Independent clinicians licensed in your state, with provider messaging and refill coordination, per its site | US-licensed clinicians (LionMD network) via async intake, monthly check-ins and provider-reviewed refills; five states require a scheduled video consultation |
| Trustpilot | No Trustpilot profile we could quote | 4.4/5 from 90 reviews (read Nov 5, 2026) |
| Recorded provider check | 2026-11-09 | 2026-10-03 |
Price by plan and term
Each rate is a per-month amount for the plan named, from the seller's own page on the date shown. A term plan's rate needs the full term; the total under it is the rate times the months.
HealthRX
| Plan or term | Semaglutide | Tirzepatide | Source and read date |
|---|---|---|---|
| Monthly plan | $125/mo | $201/mo | HealthRX page, read Nov 9, 2026 |
| 12-month plan | $97/mo$1,164 over 12 months | $177/mo$2,124 over 12 months | HealthRX page, read Nov 9, 2026 |
Read November 9, 2026 on healthrx.com/pricing and the product pages: $39 for the first month, then compounded semaglutide $125 a month or compounded tirzepatide $201 a month, renewing until canceled. The 12-month plan is shown as $97 (semaglutide) or $177 (tirzepatide) a month, with $39 due today. Its earlier plan-by-plan upfront totals (read November 6) were not shown on these pages and are not re-read, so we do not carry them. The plan price includes the provider review, medication and overnight shipping per the seller; lab charges are not stated, so they are unknown.
PlexusDx
| Plan or term | Semaglutide | Tirzepatide | Source and read date |
|---|---|---|---|
| Monthly plan | $189/mo | $289/mo | PlexusDx page, read Oct 3, 2026 |
Compounded semaglutide injections $189/mo month-to-month, $169/mo on the 3-month plan and $149/mo on the 6-month plan; compounded tirzepatide injections $289 / $269 / $249. Oral semaglutide runs $289 / $269 / $249 and oral tirzepatide $349 / $299 / $279; a low-dose Microdose GLP-1 program is $129/mo. The site does not say whether the 3- and 6-month tiers are billed up front. An optional GLP-1 & Peptide Pathways genetic test is offered for $99 (list $298) after the first program order. Read October 3, 2026.
What is included
HealthRX
Visits: consultation recorded as "Included, per its pricing page". Care: Independent clinicians licensed in your state, with provider messaging and refill coordination, per its site.
Shipping: recorded as included.
Labs: Required tests and any lab charge are not recorded.
Dose increases: A price for each dose step is not recorded.
What HealthRX lists:
- Says the plan price includes the provider review, the prescription when appropriate, the medication and overnight shipping, with no separate visit or membership fee
- Says it gives a full refund if a provider does not approve you
- Its pricing page says plans are HSA and FSA eligible
PlexusDx
Visits: consultation recorded as "Included". Care: US-licensed clinicians (LionMD network) via async intake, monthly check-ins and provider-reviewed refills; five states require a scheduled video consultation.
Shipping: recorded as included.
Labs: Required tests and any lab charge are not recorded.
Dose increases: The seller says its price stays the same as the dose rises; the full dose schedule is not independently checked.
What PlexusDx lists:
- Flat price at every dose level, so the monthly cost does not rise as your dose is titrated up
- Available in all 50 states, with injection, oral and low-dose microdose options
States served
HealthRX: 50 states
Recorded as available in all 50 states.
The record names no excluded state. Confirm yours at intake.
PlexusDx: 50 states
Recorded as available in all 50 states.
- Available in all 50 states, with injection, oral and low-dose microdose options
State-by-state costs and Medicaid notes are on the GLP-1 cost by state pages.
Drugs offered
HealthRX: compounded medication only
- Compounded Semaglutide
- Compounded Tirzepatide
Injections only on the record.
PlexusDx: compounded medication only
- Compounded Semaglutide
- Compounded Semaglutide (oral)
- Compounded Tirzepatide
- Compounded Tirzepatide (oral)
- Microdose GLP-1
An oral form is listed.
Compounded drugs are made by a pharmacy for a patient and are not the brand products. Compounded vs brand-name GLP-1.
Membership and other fees
- HealthRX: Not separately recorded; do not assume zero.
- PlexusDx: Not separately recorded; do not assume zero.
A fee missing from the record is unknown, not zero.
Cancellation and refunds
HealthRX
Recorded: cancel by emailing support, and it refunds any unshipped dose; full refund if a provider does not approve; dispensed medication cannot be returned.
- The monthly plan bills every month until canceled, with a $39 first month on either medication.
- Its pricing page says the plan price includes the provider review, medication and overnight shipping, with no separate visit or membership fee. Lab charges are not stated on the pages we read, so they are unknown. It says it refunds any unshipped dose on cancellation; dispensed medication cannot be returned.
PlexusDx
A complete refund policy and prepaid-plan cancellation rules are not recorded.
Which should you choose?
HealthRX
On the record, HealthRX suits a reader who wants the lower semaglutide monthly-plan rate, the lower tirzepatide monthly-plan rate, the lower 12-month semaglutide total and the lower 12-month tirzepatide total.
PlexusDx
On the record, PlexusDx suits a reader who wants an oral option.
Ask each provider for the full cost at your prescribed dose, required labs and visits, the dispensing pharmacy, the clinician's state license, renewal charges and written refund terms. Compare those answers with your clinician.
Compounded drugs are not FDA-approved and do not undergo FDA review for safety, effectiveness or quality before marketing. FDA source and recommendations.
HealthRX: evidence and terms
Price-only check 2026-11-09: Monthly plan: $125 semaglutide, $201 tirzepatide, after a $39 first month (pricing page and product page, read 2026-11-09). Price source.
PlexusDx: evidence and terms
HealthRX vs PlexusDx: questions
Which is cheaper, HealthRX or PlexusDx?
HealthRX is lower for semaglutide on the monthly plan: $125/mo against $189/mo at PlexusDx, a $64 gap. HealthRX is lower for tirzepatide on the monthly plan: $201/mo against $289/mo at PlexusDx, a $88 gap. These are medication and recorded program-fee subtotals; labs, dose changes and other charges may be extra.
Which costs less over a year, HealthRX or PlexusDx?
Over 12 months HealthRX is lower for semaglutide: $1,164 on the 12-month plan, against $2,268 at PlexusDx on 12 months on the monthly plan. Over 12 months HealthRX is lower for tirzepatide: $2,124 on the 12-month plan, against $3,468 at PlexusDx on 12 months on the monthly plan. A term plan commits you for the full term, so check its refund rules first.
Is HealthRX or PlexusDx available in more states?
Both are recorded in 50 states. PlexusDx: Available in all 50 states, with injection, oral and low-dose microdose options. Confirm your state at intake.
Do HealthRX and PlexusDx offer brand-name or compounded GLP-1?
HealthRX lists compounded medication only (Compounded Semaglutide, Compounded Tirzepatide). PlexusDx lists compounded medication only (Compounded Semaglutide, Compounded Semaglutide (oral), Compounded Tirzepatide, Compounded Tirzepatide (oral), Microdose GLP-1). Compounded drugs are not FDA-approved.
Does HealthRX or PlexusDx charge a membership fee?
HealthRX: Not separately recorded; do not assume zero. PlexusDx: Not separately recorded; do not assume zero.
Can you cancel HealthRX or PlexusDx at any time?
HealthRX: Recorded: cancel by emailing support, and it refunds any unshipped dose; full refund if a provider does not approve; dispensed medication cannot be returned. PlexusDx: A complete refund policy and prepaid-plan cancellation rules are not recorded.
Are the visit and shipping included with HealthRX and PlexusDx?
HealthRX: consultation recorded as "Included, per its pricing page", shipping recorded as included. PlexusDx: consultation recorded as "Included", shipping recorded as included.
Do HealthRX or PlexusDx take insurance?
Neither is recorded as accepting insurance; both are self-pay on our record.
Does HealthRX or PlexusDx offer a pill or tablet?
PlexusDx lists an oral option; HealthRX lists injections only on our record.
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