Willow vs Enhance MD: Which GLP-1 Program Is Better? (2026)
A detailed side-by-side comparison of Willow and Enhance MD to help you choose the right GLP-1 weight loss program based on pricing, medications, medical support, and more.
Quick Verdict
We recommend Enhance MD
Between these two providers, Enhance MD is our pick for most users. It offers a higher overall rating (8.3 vs 6.9), more affordable pricing, availability in all 50 states, both brand-name and compounded medication options. That said, Willow may be the better fit if you are looking for women who want a tablet option and 24/7 support and will pay a premium for it.
Enhance MD scores 8.3/10 in our independent evaluation at $212/month, while Willow scores 6.9/10 at $299/month. Both programs include a licensed physician consultation and ship medication directly to your door. Our rating considers five factors: safety and medical oversight (30%), pricing transparency (25%), cost value (20%), clinical support quality (15%), and onboarding speed (10%). We earn affiliate commissions from some providers, disclosed on this page; no provider can pay to fake safety, licensing, or hide the downsides. Prices verified April 2026.
Side-by-Side Comparison
| Feature | Willow | Enhance MD |
|---|---|---|
| Monthly Price | $299 | $212 |
| Rating | 6.9 / 10 | 8.3 / 10 |
| Medication Type | Compounded Only | Brand & Compounded |
| Insurance Accepted | No | No |
| States Available | 38 states | All 50 states |
| Consultation Fee | Free | Included |
| Shipping | Free Shipping | Free Shipping |
| Cancel Anytime | Yes | Yes |
| Medical Support | Licensed physicians, unlimited doctor access, 24/7 online care team | Board-certified physicians |
Prices reflect starting rates without insurance. Actual costs may vary by plan and medication. Last updated April 2026.
Willow: Detailed Look
Willow
Personalized GLP-1 weight loss with ongoing clinical support
Pros
- Injectable or dissolving-tablet semaglutide and tirzepatide at the same price
- Unlimited doctor access plus a 24/7 online care team
- Displays a LegitScript certification seal; HSA/FSA eligible
- Free shipping; cancel anytime (full refund if you cancel before the prescription goes to the pharmacy)
Cons
- $299/mo semaglutide and $399/mo tirzepatide — among the most expensive compounded plans we track, with no multi-month discount
- Serves 38 states — not available in AL, AK, AR, DE, KS, LA, MS, ND, RI, SD, UT or WV
- Newer platform — fewer long-term patient reviews available
Women who want a tablet option and 24/7 support and will pay a premium for it
Enhance MD: Detailed Look
Enhance MD
Physician-led weight management with NAD+ options
Pros
- Semaglutide $212/mo on the 12-month plan, same price at every dose, labs every 6 months included
- Unique NAD+ therapy option alongside GLP-1
- Board-certified physicians lead all protocols
Cons
- NAD+ weight loss claims lack strong clinical evidence
- Less transparent about which medications are compounded vs brand
Budget-conscious users interested in combination therapies
Which Should You Choose?
The right choice depends on your specific needs and priorities. Here is a quick decision framework:
Go with Enhance MD at $212/month. Semaglutide $212/mo and tirzepatide $280/mo on the 12-month plan (billed every 48 weeks); 6-month $224 / $296, 3-month $237 / $313, 1-month $249 / $329. Same price at every dose, 'no hidden fees', provider care and labs every 6 months included. A Labor Day promotion advertises up to $150 off your FIRST order only ($100 off multi-month, $50 off 1-month); the ongoing rates above are what you actually pay. A microdosing tirzepatide plan at $169/mo is capped at 1mg/week and is not a full-dose price. Verified September 6, 2026..
Enhance MD has the edge with a 8.3 rating.
Willow focuses on compounded medications at a lower price point.
Compare their support: Willow offers licensed physicians, unlimited doctor access, 24/7 online care team, while Enhance MD provides board-certified physicians.
Willow at $299/month may offer features that justify the premium.
Frequently Asked Questions
Is Willow better than Enhance MD?
Willow has a 6.9 rating while Enhance MD has a 8.3 rating. The better choice depends on your priorities — Willow is best for women who want a tablet option and 24/7 support and will pay a premium for it, while Enhance MD is best for budget-conscious users interested in combination therapies.
How much does Willow cost compared to Enhance MD?
Willow starts at $299/month (compounded semaglutide $299/mo and tirzepatide $399/mo, billed month-to-month with no plan tiers ('one time for $299 / subscribe for $299'); the same prices apply to willow's semaglutide and tirzepatide dissolving tablets. hsa/fsa eligible, free 2-day shipping, medical evaluation included. read on startwillow.com product pages september 18, 2026 — the previous $160 'starting price' matched nothing on the site.), while Enhance MD starts at $212/month (semaglutide $212/mo and tirzepatide $280/mo on the 12-month plan (billed every 48 weeks); 6-month $224 / $296, 3-month $237 / $313, 1-month $249 / $329. same price at every dose, 'no hidden fees', provider care and labs every 6 months included. a labor day promotion advertises up to $150 off your first order only ($100 off multi-month, $50 off 1-month); the ongoing rates above are what you actually pay. a microdosing tirzepatide plan at $169/mo is capped at 1mg/week and is not a full-dose price. verified september 6, 2026.).
Do Willow and Enhance MD accept insurance?
Willow does not accept insurance. Enhance MD does not accept insurance.
Which GLP-1 medications does Willow offer vs Enhance MD?
Willow offers Compounded Semaglutide (Injectable), Compounded Tirzepatide (Injectable), Compounded Semaglutide (Tablets), Compounded Tirzepatide (Tablets). Enhance MD offers Semaglutide, Tirzepatide, NAD+.
Can I cancel Willow or Enhance MD at any time?
Willow allows cancel anytime. Enhance MD also allows cancel anytime.
Are Willow and Enhance MD available in my state?
Willow is available in 38 states. Enhance MD is available in all 50 states.
Not sure Willow or Enhance MD is right for you?
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