Enhance MD vs Telos Rx: Which GLP-1 Program Is Better? (2026)
A detailed side-by-side comparison of Enhance MD and Telos Rx to help you choose the right GLP-1 weight loss program based on pricing, medications, medical support, and more.
Quick Verdict
We recommend Enhance MD
Between these two providers, Enhance MD is our pick for most users. It offers a higher overall rating (8.3 vs 8.2), availability in all 50 states, both brand-name and compounded medication options. That said, Telos Rx may be the better fit if you are looking for users specifically seeking tirzepatide — especially the oral format.
Enhance MD scores 8.3/10 in our independent evaluation at $249/month, while Telos Rx scores 8.2/10 at $99/month. Both programs include a licensed physician consultation and ship medication directly to your door. Our rating considers five factors: safety and medical oversight (30%), pricing transparency (25%), cost value (20%), clinical support quality (15%), and onboarding speed (10%). This comparison was independently produced — neither provider pays for placement or higher ratings. Prices verified April 2026.
Side-by-Side Comparison
| Feature | Enhance MD | Telos Rx |
|---|---|---|
| Monthly Price | $249 | $99 |
| Rating | 8.3 / 10 | 8.2 / 10 |
| Medication Type | Brand & Compounded | Compounded Only |
| Insurance Accepted | No | No |
| States Available | All 50 states | 47 states |
| Consultation Fee | Included | Included |
| Shipping | Free Shipping | Free Shipping |
| Cancel Anytime | Yes | Yes |
| Medical Support | Board-certified physicians | Licensed prescribers, telehealth consults |
Prices reflect starting rates without insurance. Actual costs may vary by plan and medication. Last updated April 2026.
Enhance MD: Detailed Look
Enhance MD
Physician-led weight management with NAD+ options
Pros
- Affordable entry point starting at $115/month
- Unique NAD+ therapy option alongside GLP-1
- Board-certified physicians lead all protocols
Cons
- NAD+ weight loss claims lack strong clinical evidence
- Less transparent about which medications are compounded vs brand
Budget-conscious users interested in combination therapies
Telos Rx: Detailed Look
Telos Rx
Tirzepatide-first program with oral and injection options
Pros
- Tirzepatide-specialist program (most competitors lead with semaglutide)
- Oral tirzepatide option — rare among verified programs
- Entry pricing from $99
- FDA-registered US compounding pharmacy sourcing
Cons
- Higher-dose tirzepatide plans reach $399/month
- New program with limited review history
Users specifically seeking tirzepatide — especially the oral format
Which Should You Choose?
The right choice depends on your specific needs and priorities. Here is a quick decision framework:
Go with Telos Rx at $99/month. Entry pricing from $99; tirzepatide plans up to $399/mo at higher doses.
Enhance MD has the edge with a 8.3 rating.
Telos Rx focuses on compounded medications at a lower price point.
Compare their support: Enhance MD offers board-certified physicians, while Telos Rx provides licensed prescribers, telehealth consults.
Enhance MD at $249/month may offer features that justify the premium.
Frequently Asked Questions
Is Enhance MD better than Telos Rx?
Enhance MD has a 8.3 rating while Telos Rx has a 8.2 rating. The better choice depends on your priorities — Enhance MD is best for budget-conscious users interested in combination therapies, while Telos Rx is best for users specifically seeking tirzepatide — especially the oral format.
How much does Enhance MD cost compared to Telos Rx?
Enhance MD starts at $249/month (semaglutide $249/mo; tirzepatide $379/mo; annual plans save ~15%), while Telos Rx starts at $99/month (entry pricing from $99; tirzepatide plans up to $399/mo at higher doses).
Do Enhance MD and Telos Rx accept insurance?
Enhance MD does not accept insurance. Telos Rx does not accept insurance.
Which GLP-1 medications does Enhance MD offer vs Telos Rx?
Enhance MD offers Semaglutide, Tirzepatide, NAD+. Telos Rx offers Compounded Tirzepatide, Compounded Semaglutide, Oral Tirzepatide.
Can I cancel Enhance MD or Telos Rx at any time?
Enhance MD allows cancel anytime. Telos Rx also allows cancel anytime.
Are Enhance MD and Telos Rx available in my state?
Enhance MD is available in all 50 states. Telos Rx is available in 47 states.
Not sure Enhance MD or Telos Rx is right for you?
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