Oak Longevity vs Enhance MD: Which GLP-1 Program Is Better? (2026)
A detailed side-by-side comparison of Oak Longevity and Enhance MD to help you choose the right GLP-1 weight loss program based on pricing, medications, medical support, and more.
Quick Verdict
We recommend Oak Longevity
Between these two providers, Oak Longevity is our pick for most users. It offers a higher overall rating (8.9 vs 8.3), more affordable pricing. That said, Enhance MD may be the better fit if you are looking for budget-conscious users interested in combination therapies.
Oak Longevity scores 8.9/10 in our independent evaluation at $119/month, while Enhance MD scores 8.3/10 at $212/month. Both programs include a licensed physician consultation and ship medication directly to your door. Our rating considers five factors: safety and medical oversight (30%), pricing transparency (25%), cost value (20%), clinical support quality (15%), and onboarding speed (10%). We earn affiliate commissions from some providers, disclosed on this page; no provider can pay to fake safety, licensing, or hide the downsides. Prices verified April 2026.
Side-by-Side Comparison
| Feature | Oak Longevity | Enhance MD |
|---|---|---|
| Monthly Price | $119 | $212 |
| Rating | 8.9 / 10 | 8.3 / 10 |
| Medication Type | Compounded Only | Brand & Compounded |
| Insurance Accepted | No | No |
| States Available | All 50 states | All 50 states |
| Consultation Fee | Included | Included |
| Shipping | Free Shipping | Free Shipping |
| Cancel Anytime | Yes | Yes |
| Medical Support | Board-certified physicians, free health coaching, responsive care team | Board-certified physicians |
Prices reflect starting rates without insurance. Actual costs may vary by plan and medication. Last updated April 2026.
Oak Longevity: Detailed Look
Oak Longevity
Affordable compounded semaglutide from $119/mo with free shipping and health coaching
Pros
- Compounded semaglutide from $119/mo and tirzepatide from $185/mo (12-month plan)
- Free shipping + free health coaching included
- No membership fee — the plan price includes the medication
- Same-day approval with 10,000+ satisfied patients
Cons
- Compounded medications only — no brand-name options
- Newer platform with limited independent reviews
Budget-conscious users who want the lowest price with health coaching and no membership fees
Enhance MD: Detailed Look
Enhance MD
Physician-led weight management with NAD+ options
Pros
- Semaglutide $212/mo on the 12-month plan, same price at every dose, labs every 6 months included
- Unique NAD+ therapy option alongside GLP-1
- Board-certified physicians lead all protocols
Cons
- NAD+ weight loss claims lack strong clinical evidence
- Less transparent about which medications are compounded vs brand
Budget-conscious users interested in combination therapies
Which Should You Choose?
The right choice depends on your specific needs and priorities. Here is a quick decision framework:
Go with Oak Longevity at $119/month. Compounded semaglutide from $119/mo and compounded tirzepatide from $185/mo, both on a 12-month plan — the headline on Oak's own /semaglutide and /tirzepatide product pages (read September 25, 2026: 'Compounded prices shown on 12-month plans'; shorter plans are available and the exact price is confirmed before checkout, but the shorter-plan prices are not published). The homepage also says 'GLP-1 Treatments for weight loss from $89/mo' without naming the product; we rank on the product-page figures. Until September 2026 Oak advertised $167/mo semaglutide and published no tirzepatide price..
Oak Longevity has the edge with a 8.9 rating.
Oak Longevity focuses on compounded medications at a lower price point.
Compare their support: Oak Longevity offers board-certified physicians, free health coaching, responsive care team, while Enhance MD provides board-certified physicians.
Enhance MD at $212/month may offer features that justify the premium.
Frequently Asked Questions
Is Oak Longevity better than Enhance MD?
Oak Longevity has a 8.9 rating while Enhance MD has a 8.3 rating. The better choice depends on your priorities — Oak Longevity is best for budget-conscious users who want the lowest price with health coaching and no membership fees, while Enhance MD is best for budget-conscious users interested in combination therapies.
How much does Oak Longevity cost compared to Enhance MD?
Oak Longevity starts at $119/month (compounded semaglutide from $119/mo and compounded tirzepatide from $185/mo, both on a 12-month plan — the headline on oak's own /semaglutide and /tirzepatide product pages (read september 25, 2026: 'compounded prices shown on 12-month plans'; shorter plans are available and the exact price is confirmed before checkout, but the shorter-plan prices are not published). the homepage also says 'glp-1 treatments for weight loss from $89/mo' without naming the product; we rank on the product-page figures. until september 2026 oak advertised $167/mo semaglutide and published no tirzepatide price.), while Enhance MD starts at $212/month (semaglutide $212/mo and tirzepatide $280/mo on the 12-month plan (billed every 48 weeks); 6-month $224 / $296, 3-month $237 / $313, 1-month $249 / $329. same price at every dose, 'no hidden fees', provider care and labs every 6 months included. a labor day promotion advertises up to $150 off your first order only ($100 off multi-month, $50 off 1-month); the ongoing rates above are what you actually pay. a microdosing tirzepatide plan at $169/mo is capped at 1mg/week and is not a full-dose price. verified september 6, 2026.).
Do Oak Longevity and Enhance MD accept insurance?
Oak Longevity does not accept insurance. Enhance MD does not accept insurance.
Which GLP-1 medications does Oak Longevity offer vs Enhance MD?
Oak Longevity offers Compounded Semaglutide, Compounded Tirzepatide. Enhance MD offers Semaglutide, Tirzepatide, NAD+.
Can I cancel Oak Longevity or Enhance MD at any time?
Oak Longevity allows cancel anytime. Enhance MD also allows cancel anytime.
Are Oak Longevity and Enhance MD available in my state?
Oak Longevity is available in all 50 states. Enhance MD is available in all 50 states.
Not sure Oak Longevity or Enhance MD is right for you?
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