Direct Meds GLP-1 vs Willow
Recorded prices, access and terms.
The short answer
- Cheapest to start, semaglutide: Direct Meds GLP-1 is lower for semaglutide on the monthly plan: $249/mo against $299/mo at Willow, a $50 gap.
- Cheapest to start, tirzepatide: Direct Meds GLP-1 is lower for tirzepatide on the monthly plan: $297/mo against $399/mo at Willow, a $102 gap.
- Cheapest over 12 months, semaglutide: Over 12 months Direct Meds GLP-1 is lower for semaglutide: $2,988 on 12 months on the monthly plan, against $3,588 at Willow on 12 months on the monthly plan.
- Cheapest over 12 months, tirzepatide: Over 12 months Direct Meds GLP-1 is lower for tirzepatide: $3,564 on 12 months on the monthly plan, against $4,788 at Willow on 12 months on the monthly plan.
- Broadest availability: Direct Meds GLP-1 is recorded in 45 states, Willow in 38.
- Drugs: Direct Meds GLP-1 lists compounded medication only; Willow lists compounded medication only.
Price lines compare recorded monthly-plan subtotals and term totals, as on our price pages. A lower recorded rate is not a complete cost: labs, dose changes and the amount due today can differ.
Decision table
The entries below are recorded provider statements unless a regulatory source is linked. A provider webpage does not independently verify its licenses or quality. Direct Meds GLP-1 source · Willow source.
| Compare | Direct Meds GLP-1 | Willow |
|---|---|---|
| Recorded monthly-plan price | $249/mo semaglutide, $297/mo tirzepatide | $299/mo semaglutide, $399/mo tirzepatide |
| Recorded medication/program subtotal | Recorded medication and program subtotal: semaglutide: $249/month; tirzepatide: $297/month. Other required fees, labs, dose changes and renewal terms are not established. This is not a verified all-in treatment cost. | Recorded medication and program subtotal: semaglutide: $299/month; tirzepatide: $399/month. Other required fees, labs, dose changes and renewal terms are not established. This is not a verified all-in treatment cost. |
| Lowest 12-month total on the record | semaglutide $2,988 (12 months on the monthly plan); tirzepatide $3,564 (12 months on the monthly plan) | semaglutide $3,588 (12 months on the monthly plan); tirzepatide $4,788 (12 months on the monthly plan) |
| Full required monthly cost | Not established: consultation, labs, membership, dose changes and shipping must be checked | Not established: consultation, labs, membership, dose changes and shipping must be checked |
| Drug type listed | Compounded | Compounded |
| Oral option | Listed | Listed |
| Consultation | Included in the record; current conditions unconfirmed | Free in the record; current conditions unconfirmed |
| Membership or program fee | Not separately recorded; do not assume zero. | Not separately recorded; do not assume zero. |
| Shipping | Recorded as included; confirm for your address | Recorded as included; confirm for your address |
| Labs | Required tests and any lab charge are not recorded. | Required tests and any lab charge are not recorded. |
| Insurance | Self-pay on the record | Self-pay on the record |
| Pharmacy license | Not independently verified. Obtain the dispensing pharmacy name and verify its state license. | Not independently verified. Obtain the dispensing pharmacy name and verify its state license. |
| Reported states | 45; confirm eligibility and clinician licensing in your state | 38; confirm eligibility and clinician licensing in your state |
| Cancellation | Cancellation reported; notice, minimum term and refund conditions unconfirmed | Cancellation reported; notice, minimum term and refund conditions unconfirmed |
| Clinician/support as reported | Licensed providers | Licensed physicians, unlimited doctor access, 24/7 online care team |
| Trustpilot | 4.5/5 from 17,622 reviews (read Nov 5, 2026) | 4.1/5 from 386 reviews (read Nov 5, 2026) |
| Recorded provider check | 2026-09-13 | 2026-11-06 |
Price by plan and term
Each rate is a per-month amount for the plan named, from the seller's own page on the date shown. A term plan's rate needs the full term; the total under it is the rate times the months.
Direct Meds GLP-1
| Plan or term | Semaglutide | Tirzepatide | Source and read date |
|---|---|---|---|
| Monthly plan | $249/mo | $297/mo | Direct Meds GLP-1 page, read Sep 13, 2026 |
Terms (April 16, 2026): a prescription order can be cancelled only within 24 hours of placing it, subscriptions bill every 30 days and can be cancelled up to 48 hours before the next processing date in the portal, and medication already received is not refundable.
Willow
| Plan or term | Semaglutide | Tirzepatide | Source and read date |
|---|---|---|---|
| Monthly plan | $299/mo | $399/mo | Willow page, read Nov 6, 2026 |
Compounded semaglutide $299/mo and tirzepatide $399/mo, billed month-to-month with no plan tiers ('one time for $299 / subscribe for $299'); the same prices apply to Willow's semaglutide and tirzepatide dissolving tablets. HSA/FSA eligible, free 2-day shipping, medical evaluation included. Read on startwillow.com product pages September 18, 2026: the previous $160 'starting price' matched nothing on the site.
What is included
Direct Meds GLP-1
Visits: consultation recorded as "Included". Care: Licensed providers.
Shipping: recorded as included.
Labs: Required tests and any lab charge are not recorded.
Dose increases: A price for each dose step is not recorded.
What Direct Meds GLP-1 lists:
- Straightforward, simple enrollment process
Willow
Visits: consultation recorded as "Free". Care: Licensed physicians, unlimited doctor access, 24/7 online care team.
Shipping: recorded as included.
Labs: Required tests and any lab charge are not recorded.
Dose increases: A price for each dose step is not recorded.
What Willow lists:
- Injectable or dissolving-tablet semaglutide and tirzepatide at the same price
- Unlimited doctor access plus a 24/7 online care team
- Free shipping; cancel anytime (full refund if you cancel before the prescription goes to the pharmacy)
States served
Direct Meds GLP-1: 45 states
Recorded as available in 45 states.
The record names no excluded state. Confirm yours at intake.
Willow: 38 states
Recorded as available in 38 states.
- Serves 38 states: not available in AL, AK, AR, DE, KS, LA, MS, ND, RI, SD, UT or WV
State-by-state costs and Medicaid notes are on the GLP-1 cost by state pages.
Drugs offered
Direct Meds GLP-1: compounded medication only
- Compounded Semaglutide (Sublingual)
- Compounded Semaglutide (Injectable)
- Compounded Tirzepatide
An oral form is listed.
Willow: compounded medication only
- Compounded Semaglutide (Injectable)
- Compounded Tirzepatide (Injectable)
- Compounded Semaglutide (Tablets)
- Compounded Tirzepatide (Tablets)
An oral form is listed.
Compounded drugs are made by a pharmacy for a patient and are not the brand products. Compounded vs brand-name GLP-1.
Membership and other fees
- Direct Meds GLP-1: Not separately recorded; do not assume zero.
- Willow: Not separately recorded; do not assume zero.
A fee missing from the record is unknown, not zero.
Cancellation and refunds
Direct Meds GLP-1
Recorded: prescription orders cancellable within 24 hours; subscription cancellation at least 48 hours before processing. Received medication is non-refundable.
Willow
Recorded: full refund only before prescription reaches pharmacy. Later cancellation/refund rights need confirmation.
Which should you choose?
Direct Meds GLP-1
On the record, Direct Meds GLP-1 suits a reader who wants the lower semaglutide monthly-plan rate, the lower tirzepatide monthly-plan rate, the lower 12-month semaglutide total, the lower 12-month tirzepatide total and more states on the record (45 against 38).
Willow
On price, states and drug type the record does not put Willow ahead of Direct Meds GLP-1. It suits a reader who prefers its care model: licensed physicians, unlimited doctor access, 24/7 online care team.
Ask each provider for the full cost at your prescribed dose, required labs and visits, the dispensing pharmacy, the clinician's state license, renewal charges and written refund terms. Compare those answers with your clinician.
Compounded drugs are not FDA-approved and do not undergo FDA review for safety, effectiveness or quality before marketing. FDA source and recommendations.
Direct Meds GLP-1: evidence and terms
Recorded FDA letter (2025-09-09): FDA found claims on directmeds.com that its compounded semaglutide and tirzepatide contain 'the same active ingredient' as the brand drugs false or misleading, making the products misbranded under FD&C Act sections 502(a) and 502(bb). FDA letter.
Read Direct Meds GLP-1's sourced record · Direct Meds GLP-1 source
Willow: evidence and terms
Price-only check 2026-11-06: Homepage FAQ: treatment plans start at $299 per month. The $399 tirzepatide figure is from its product pages, read September 18. Price source.
Direct Meds GLP-1 vs Willow: questions
Which is cheaper, Direct Meds GLP-1 or Willow?
Direct Meds GLP-1 is lower for semaglutide on the monthly plan: $249/mo against $299/mo at Willow, a $50 gap. Direct Meds GLP-1 is lower for tirzepatide on the monthly plan: $297/mo against $399/mo at Willow, a $102 gap. These are medication and recorded program-fee subtotals; labs, dose changes and other charges may be extra.
Which costs less over a year, Direct Meds GLP-1 or Willow?
Over 12 months Direct Meds GLP-1 is lower for semaglutide: $2,988 on 12 months on the monthly plan, against $3,588 at Willow on 12 months on the monthly plan. Over 12 months Direct Meds GLP-1 is lower for tirzepatide: $3,564 on 12 months on the monthly plan, against $4,788 at Willow on 12 months on the monthly plan. A term plan commits you for the full term, so check its refund rules first.
Is Direct Meds GLP-1 or Willow available in more states?
Direct Meds GLP-1 is recorded in more states: 45 against 38. Willow: Serves 38 states: not available in AL, AK, AR, DE, KS, LA, MS, ND, RI, SD, UT or WV. Confirm your state at intake.
Do Direct Meds GLP-1 and Willow offer brand-name or compounded GLP-1?
Direct Meds GLP-1 lists compounded medication only (Compounded Semaglutide (Sublingual), Compounded Semaglutide (Injectable), Compounded Tirzepatide). Willow lists compounded medication only (Compounded Semaglutide (Injectable), Compounded Tirzepatide (Injectable), Compounded Semaglutide (Tablets), Compounded Tirzepatide (Tablets)). Compounded drugs are not FDA-approved.
Does Direct Meds GLP-1 or Willow charge a membership fee?
Direct Meds GLP-1: Not separately recorded; do not assume zero. Willow: Not separately recorded; do not assume zero.
Can you cancel Direct Meds GLP-1 or Willow at any time?
Direct Meds GLP-1: Recorded: prescription orders cancellable within 24 hours; subscription cancellation at least 48 hours before processing. Received medication is non-refundable. Willow: Recorded: full refund only before prescription reaches pharmacy. Later cancellation/refund rights need confirmation.
Are the visit and shipping included with Direct Meds GLP-1 and Willow?
Direct Meds GLP-1: consultation recorded as "Included", shipping recorded as included. Willow: consultation recorded as "Free", shipping recorded as included.
Do Direct Meds GLP-1 or Willow take insurance?
Neither is recorded as accepting insurance; both are self-pay on our record.
Does Direct Meds GLP-1 or Willow offer a pill or tablet?
Both list an oral option alongside injections. Check which drug and form each one prescribes for you.
Compare the full provider directory · Compare recorded price subtotals