Sesame Care vs Amble: Which GLP-1 Program Is Better? (2026)
A detailed side-by-side comparison of Sesame Care and Amble to help you choose the right GLP-1 weight loss program based on pricing, medications, medical support, and more.
Quick Verdict
We recommend Amble
Between these two providers, Amble is our pick for most users. It offers a higher overall rating (7.6 vs 7.2), more affordable pricing. That said, Sesame Care may be the better fit if you are looking for people who specifically want brand-name fda-approved glp-1s and will commit to a year of care — not the cheapest route, and no compounded option.
Amble scores 7.6/10 in our independent evaluation at $135/month, while Sesame Care scores 7.2/10 at $208/month. Both programs include a licensed physician consultation and ship medication directly to your door. Our rating considers five factors: safety and medical oversight (30%), pricing transparency (25%), cost value (20%), clinical support quality (15%), and onboarding speed (10%). We earn affiliate commissions from some providers, disclosed on this page; no provider can pay to fake safety, licensing, or hide the downsides. Prices verified April 2026.
Side-by-Side Comparison
| Feature | Sesame Care | Amble |
|---|---|---|
| Monthly Price | $208 | $135 |
| Rating | 7.2 / 10 | 7.6 / 10 |
| Medication Type | Brand-Name Only | Compounded Only |
| Insurance Accepted | Yes | No |
| States Available | All 50 states | All 50 states |
| Consultation Fee | $59/mo care subscription (12-month commitment) | Included |
| Shipping | Paid | Free Shipping |
| Cancel Anytime | Yes | No |
| Medical Support | Licensed physicians, per-visit model | Unnamed licensed physicians via async review, 24/7 messaging and scheduled check-ins |
Prices reflect starting rates without insurance. Actual costs may vary by plan and medication. Last updated April 2026.
Sesame Care: Detailed Look
Sesame Care
Affordable telehealth marketplace connecting patients with doctors from $25
Pros
- Lowest consultation cost — visits from just $25
- Prescribes brand-name FDA-approved medications
- Transparent per-visit pricing with no subscriptions
- Wide network of licensed physicians across all 50 states
Cons
- Medication cost is separate and not included in visit fee
- No compounded options — brand-name only (higher drug cost)
People who specifically want brand-name FDA-approved GLP-1s and will commit to a year of care — not the cheapest route, and no compounded option
Amble: Detailed Look
Amble
Ohio-based compounded GLP-1 telehealth with no membership fee and prepaid multi-month plans
Pros
- No membership fee — physician review, supplies, cold shipping and 24/7 messaging are included in the plan price
- Trustpilot 4.6/5 from 4,487 reviews on the joinamble.com profile (81% five-star), claimed and answered
- Available in all 50 states with exclusions; a video or audio visit is required only in NM, KS, WV, LA and MS
- Amble Cares program (May 2026) advertises up to 50% lower cost for patients verified as low-income
Cons
- BBB rating F, not accredited: 363 complaints in three years and 191 marked 'failure to respond' as of September 2026
- Prepaid multi-month plans are non-refundable once medication ships; 15 days' notice to cancel; $100 fee to cancel a prescribed, unshipped order; all medication sales final
- Homepage advertises 'plans starting at $99 per month' but the cheapest GLP-1 plan on the site is $135/month
- No named medical director and no named dispensing pharmacy; the Terms state Amble does not practise medicine and only facilitates access to third-party providers
- Novo Nordisk sued Amble Health in May 2025 over its compounded-semaglutide marketing; the case was dismissed in March 2026 for lack of standing, without prejudice — not a ruling on the merits
cash-pay buyers who want compounded semaglutide with no membership fee and will prepay a 3- or 6-month plan they cannot refund
Which Should You Choose?
The right choice depends on your specific needs and priorities. Here is a quick decision framework:
Go with Amble at $135/month. Compounded GLP-1 injections at $179 month-to-month, $160/mo on a 3-month plan and $135/mo on a 6-month plan (first plan table on joinamble.com/glp-1-injections; a second table on the same page lists 12 months at $135 and prices the 6-month tier at $145 — two six-month prices on one page). The main page shows ONE price table for 'compounded GLP-1' with no separate tirzepatide price; a landing page prices compounded tirzepatide (GLP-1 + GIP) at $229–$250/mo. The homepage advertises 'plans starting at $99 per month', but no $99 GLP-1 plan exists anywhere on the site — the floor is $135. No membership fee: physician review, supplies, cold shipping and check-ins are included. Multi-month plans are paid upfront and non-refundable once medication is dispensed; cancellations need 15 days' notice; a $100 fee applies to cancel a prescribed order before it ships; all medication sales are final. Verified September 7, 2026..
Amble has the edge with a 7.6 rating.
Sesame Care accepts insurance, which can significantly reduce your out-of-pocket cost.
Choose Sesame Care which exclusively prescribes brand-name medications.
Amble focuses on compounded medications at a lower price point.
Compare their support: Sesame Care offers licensed physicians, per-visit model, while Amble provides unnamed licensed physicians via async review, 24/7 messaging and scheduled check-ins.
Sesame Care at $208/month may offer features that justify the premium.
Frequently Asked Questions
Is Sesame Care better than Amble?
Sesame Care has a 7.2 rating while Amble has a 7.6 rating. The better choice depends on your priorities — Sesame Care is best for people who specifically want brand-name fda-approved glp-1s and will commit to a year of care — not the cheapest route, and no compounded option, while Amble is best for cash-pay buyers who want compounded semaglutide with no membership fee and will prepay a 3- or 6-month plan they cannot refund.
How much does Sesame Care cost compared to Amble?
Sesame Care starts at $208/month (sesame has moved to a "success by sesame" subscription: $59/mo for care (priced on a 12-month commitment) plus medication billed separately — wegovy from $149/mo brings the all-in to roughly $208/mo, and zepbound from $299/mo to roughly $358/mo. brand-name fda-approved medication only; sesame no longer offers a compounded option, so it does not appear in our compounded price ladders. sesame notes medication pricing may vary by treatment, dose, pharmacy and provider, so these are floors rather than guarantees. verified august 31, 2026.), while Amble starts at $135/month (compounded glp-1 injections at $179 month-to-month, $160/mo on a 3-month plan and $135/mo on a 6-month plan (first plan table on joinamble.com/glp-1-injections; a second table on the same page lists 12 months at $135 and prices the 6-month tier at $145 — two six-month prices on one page). the main page shows one price table for 'compounded glp-1' with no separate tirzepatide price; a landing page prices compounded tirzepatide (glp-1 + gip) at $229–$250/mo. the homepage advertises 'plans starting at $99 per month', but no $99 glp-1 plan exists anywhere on the site — the floor is $135. no membership fee: physician review, supplies, cold shipping and check-ins are included. multi-month plans are paid upfront and non-refundable once medication is dispensed; cancellations need 15 days' notice; a $100 fee applies to cancel a prescribed order before it ships; all medication sales are final. verified september 7, 2026.).
Do Sesame Care and Amble accept insurance?
Sesame Care accepts insurance. Amble does not accept insurance.
Which GLP-1 medications does Sesame Care offer vs Amble?
Sesame Care offers Wegovy, Wegovy HD, Wegovy (oral), Zepbound, Zepbound KwikPen, Foundayo. Amble offers Compounded Semaglutide, Compounded Tirzepatide.
Can I cancel Sesame Care or Amble at any time?
Sesame Care allows cancel anytime. Amble may have cancellation restrictions.
Are Sesame Care and Amble available in my state?
Sesame Care is available in all 50 states. Amble is available in all 50 states.
Not sure Sesame Care or Amble is right for you?
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