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GLP-1 Coverage & Costs in Mississippi (2026)

$79/month (Embody, compounded semaglutide, monthly plan) is the lowest monthly-plan price we have recorded among the programs on this page. Embody lists 48 states and our records do not name them, so confirm Mississippi at intake.

The lowest recorded compounded tirzepatide price is $129/month (Embody, monthly plan). Among programs recorded as available in all 50 states, the lowest is $139/month (AgelessRx, compounded semaglutide, monthly plan). 6 of the 49 programs listed have no recorded price. Recorded prices cover medication and known program fees, not a verified total.

Medicaid: covered as of January 2026 (KFF)
Eduard Cristea
Eduard Cristea
Published: |Updated:

Mississippi Medicaid Coverage for GLP-1

Medicaid: covered as of January 2026 (KFF)

KFF's map lists Mississippi among the 13 state programs covering GLP-1s for obesity under fee-for-service as of January 2026. Rules and later changes are not on that map, so confirm with the state Medicaid agency or your plan.

Mississippi Medicaid GLP-1 Prescriptions in 2025

Prescriptions paid

61,646

Rank of 51

#33

Medicaid paid, before rebates

$69.8 million

Most-filled product

Wegovy

Mississippi Medicaid paid for 61,646 GLP-1 prescriptions in 2025, 0.5% of the 11.26 million paid nationally and number 33 of 51 (50 states and DC). It reimbursed pharmacies $69.8 million before manufacturer rebates, about $1,132 per prescription, and the most-filled product was Wegovy. These counts include diabetes prescriptions, not only weight loss. Wegovy, Zepbound and Saxenda, the brands approved for chronic weight management, made up 32,234 of those prescriptions (52.3%). Wegovy and Zepbound also carry other approved uses, so this is an upper bound on weight-loss use, not a count of it.

From 2021 to 2025, Mississippi Medicaid GLP-1 prescriptions went from 13,364 to 61,646, 4.6 times the 2021 count. From 2024 to 2025 the count rose by 20,507.

2021

13,364

2022

17,648

2023

29,736

2024

41,139

2025

61,646

ProductMS Medicaid prescriptions, 2025Share
Wegovy31,78551.6%
Trulicity22,72136.9%
Ozempic2,4914%
Mounjaro2,2573.7%
Victoza1,4762.4%
Liraglutide (generic)3000.5%
Saxenda2750.4%
Zepbound1740.3%
Rybelsus1290.2%
Byetta380.1%

Source: CMS State Drug Utilization Data, 2025 (updated July 13, 2026), fee-for-service and managed care, all four quarters, compiled in our network's PriceTracker GLP-1 state table (read October 4, 2026); 2021 to 2024 summed by us from CMS's own yearly datasets with the same method, read November 9, 2026. CMS hides rows under 11 prescriptions, so small counts are slightly low. CMS publishes no per-enrollee rate here, so a total reflects the size of the program as much as use.

Mississippi Employee Plan and Insurer GLP-1 Rules

Mississippi State and School Employees' Health Insurance Plan

Does not cover GLP-1s for weight loss

Mississippi's State and School Employees' plan excludes Wegovy and other drugs used for weight loss or obesity. Wegovy and Zepbound are considered only for their other FDA-approved uses, such as obstructive sleep apnea for Zepbound.

We have no Mississippiinsurer policy on record yet. Most commercial plans decide GLP-1 coverage plan by plan, so the employer's choice matters as much as the insurer.

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Telehealth Programs to Check for Mississippi

We list 49 programs here. 21 are recorded as available in all 50 states. 7 more publish their own state list, summarized below for Mississippi. The rest record a state count without naming the states, so confirm Mississippi with the program at intake before you pay.

What Programs' Own Pages Say About Mississippi

6 of the 8 programs whose own pages name the states they serve include Mississippi: SnagRx, Strut Health, Wellorithm, MEDGm, TelosRx, Trimi. Willow and MangoRx do not list Mississippi. Pages read November 9, 2026. This is what each seller states about availability, not a licensing check.

ProgramMississippi
WillowNot served MS, per its page
SnagRxServes MS
Strut HealthShips to MS
MangoRxDoes not ship to MS, per its page
WellorithmServes MS
MEDGmServes MS
TelosRxServes MS
TrimiServes MS

Trimi's state table lists Mississippi as served through the Arora Health network. Visit format there: Online evaluation through the Arora Health network. For the Mississippi telehealth law, the table says "Pending confirmation". That citation is Trimi's, not our legal reading. Trimi state table, read November 9, 2026.

Programs on Our List, in Published Order

Compounded GLP-1 care with one-month and prepaid plans

Personalized GLP-1 consultations with tailored prescriptions and ongoing physician support

Affordable compounded semaglutide from $119/mo with free shipping and health coaching

From $119/mo semaglutide, from $185/mo tirzepatide, 12-month planCompounded Semaglutide, Compounded TirzepatideAll 50 States

Personalized GLP-1 weight loss with licensed providers and nationwide coverage

45 more programs on our list: 19 recorded as available in all 50 states, 7 with a state list shown in the table above, and 19 with a state count but no published list we have read. Compare all of them side by side.

Estimated GLP-1 Costs in Mississippi

Best Value

Telehealth (Compounded)

$79 to $399/mo

Recorded monthly-plan prices for compounded semaglutide and tirzepatide. Availability varies by program, so confirm your state at intake.

Wegovy

Brand prices with and without insurance.

Zepbound

List, LillyDirect and savings card prices.

No insurance

Self-pay GLP-1 options without coverage.

The compounded range is our recorded monthly-plan prices, the same in every state. Brand and insurance costs depend on the plan, so we link the pages that carry their sources. Compounded medications are not FDA-approved.

Medicare Part D GLP-1 Claims in Mississippi, 2024

Mississippi prescribers wrote 249,278 Medicare Part D GLP-1 claims in 2024, number 29 of 51, with $310.3 million in gross drug cost before rebates. Ozempic led with 127,548 claims for 24,310 enrollees. Wegovy had 2,364 claims. Part D did not pay for weight loss alone in 2024, so these fills are for diabetes and other approved uses.

ProductMS Part D claimsEnrollees
Ozempic127,54824,310
Mounjaro64,36411,806
Trulicity35,3756,823
Rybelsus13,4073,207
Victoza4,344Not given
Wegovy2,364665
Bydureon Bcise1,525266
Liraglutide275129
Byetta7618

Source: CMS Medicare Part D Prescribers by Geography and Drug, 2024 (updated May 21, 2026), state rows, read November 9, 2026. The state is the prescriber's. Claims include refills, and enrollees are not added across products because one person can fill two.

Now Live — Launched July 1, 2026

Medicare GLP-1 Bridge Program in Mississippi

The Bridge is national, so the rules are the same in Mississippi as everywhere: eligible Part D enrollees pay $50/month for Foundayo, Wegovy or Zepbound KwikPen, subject to BMI rules and exclusions. Medicare fact sheet.

Patient Cost

$50/mo

Launch Date

July 1, 2026

Runs Through

Dec 31, 2027

Read the Full Medicare Guide

How Mississippi Compares to Other South States

Medicaid coverage of GLP-1s for obesity is optional for states, so the answer differs by state. Here is how Mississippi and its neighbors in the South are recorded:

StateMedicaid and GLP-1s for obesityMedicaid GLP-1 Rx, 2025
Mississippi (this page)Covered, January 2026 (KFF)61,646
ArkansasNot covered24,039
LouisianaNot covered230,117
OklahomaNot covered82,353
TexasNot covered172,203

Our recorded telehealth prices are not state-specific: $79 to $399/month on monthly plans. Medicaid and marketplace coverage is what varies.

KFF counted 13 state Medicaid programs covering GLP-1s for obesity under fee-for-service as of January 2026. Managed care plans may differ. Later counts may be lower: The RX Index, an independent tracker, listed 11 in a July 10, 2026 snapshot and says that is not a current national count. Sources read November 6, 2026. Policies change, so confirm with your state Medicaid agency or plan.

If Your Insurance Denies GLP-1 Coverage in Mississippi

Commercial plans offer an internal appeal, then external review; Mississippi Medicaid enrollees can ask for a fair hearing. The denial letter names the deadlines.

How to Check Your Specific Plan in Mississippi

  • Mississippi Medicaid: Medicaid: covered as of January 2026 (KFF). Ask your Medicaid plan for its drug list and prior authorization rules, or find the state agency on Medicaid.gov's state contacts.
  • State employees: Mississippi State and School Employees' Health Insurance Plan, does not cover glp-1s for weight loss per the documents cited above. Confirm with the plan before you fill a prescription.
  • Any other plan: call the number on your card and ask whether Wegovy or Zepbound is covered for weight loss, which tier it sits on, and what prior authorization needs. Get the answer in writing.

Find the Right GLP-1 Provider in Mississippi

Answer a few questions and we'll match you with the best GLP-1 program for your budget, insurance, and goals in Mississippi.

Frequently Asked Questions — Mississippi

Does Mississippi Medicaid cover GLP-1 medications for weight loss?
KFF's map lists Mississippi among the 13 state programs covering GLP-1s for obesity under fee-for-service as of January 2026. Rules and later changes are not on that map, so confirm with the state Medicaid agency or your plan. Contact your Medicaid plan for its drug list and prior authorization requirements.
How many GLP-1 prescriptions did Mississippi Medicaid pay for in 2025?
Mississippi Medicaid paid for 61,646 GLP-1 prescriptions in 2025, 0.5% of the 11.26 million paid nationally and number 33 of 51 (50 states and DC). It reimbursed pharmacies $69.8 million before manufacturer rebates, about $1,132 per prescription, and the most-filled product was Wegovy. These counts include diabetes prescriptions, not only weight loss. Wegovy, Zepbound and Saxenda, the brands approved for chronic weight management, made up 32,234 of those prescriptions (52.3%). Wegovy and Zepbound also carry other approved uses, so this is an upper bound on weight-loss use, not a count of it. From 2021 to 2025, Mississippi Medicaid GLP-1 prescriptions went from 13,364 to 61,646, 4.6 times the 2021 count. From 2024 to 2025 the count rose by 20,507. Source: CMS State Drug Utilization Data, 2025 (updated July 13, 2026).
How many Medicare Part D GLP-1 claims were there in Mississippi in 2024?
Mississippi prescribers wrote 249,278 Medicare Part D GLP-1 claims in 2024, number 29 of 51, with $310.3 million in gross drug cost before rebates. Ozempic led with 127,548 claims for 24,310 enrollees. Wegovy had 2,364 claims. Part D did not pay for weight loss alone in 2024, so these fills are for diabetes and other approved uses. Source: CMS Medicare Part D Prescribers by Geography and Drug, 2024 (updated May 21, 2026).
Does the Mississippi state employee health plan cover GLP-1s for weight loss?
Mississippi State and School Employees' Health Insurance Plan: does not cover glp-1s for weight loss. Mississippi's State and School Employees' plan excludes Wegovy and other drugs used for weight loss or obesity. Wegovy and Zepbound are considered only for their other FDA-approved uses, such as obstructive sleep apnea for Zepbound. Source: Mississippi Department of Finance and Administration, read October 29, 2026.
What is the cheapest way to get GLP-1 medication in Mississippi?
The lowest monthly-plan price we have recorded among programs on this page is $79/month (Embody, compounded semaglutide, monthly plan). Embody lists 48 states and our records do not name them, so confirm Mississippi at intake. Medicare Part D enrollees who qualify can get Foundayo, Wegovy or Zepbound KwikPen for $50/month through the Bridge.
Which online GLP-1 programs serve Mississippi?
6 of the 8 programs whose own pages name the states they serve include Mississippi: SnagRx, Strut Health, Wellorithm, MEDGm, TelosRx, Trimi. Willow and MangoRx do not list Mississippi. Pages read November 9, 2026. For the other programs on this page, confirm Mississippi at intake before you pay.
Does Medicare cover GLP-1s in Mississippi?
Yes for eligible Part D enrollees in Mississippi: $50/month through the Medicare GLP-1 Bridge, July 1, 2026 to December 31, 2027, under the BMI rules in the Medicare section above.

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Embody (paid link)

from $49/mo, 12-month plan

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