TrimRx vs TMates: Which GLP-1 Program Is Better? (2026)
A detailed side-by-side comparison of TrimRx and TMates to help you choose the right GLP-1 weight loss program based on pricing, medications, medical support, and more.
Quick Verdict
We recommend TrimRx
Between these two providers, TrimRx is our pick for most users. It offers a higher overall rating (8.4 vs 7.8), more affordable pricing. That said, TMates may be the better fit if you are looking for users with insurance who want a coached glp-1 program with multiple medication options.
Side-by-Side Comparison
| Feature | TrimRx | TMates |
|---|---|---|
| Monthly Price | $179 | $199 |
| Rating | 8.4 / 10 | 7.8 / 10 |
| Medication Type | Compounded Only | Compounded Only |
| Insurance Accepted | No | Yes |
| States Available | 45 states | 45 states |
| Consultation Fee | Free | Included |
| Shipping | Free Shipping | Free Shipping |
| Cancel Anytime | Yes | Yes |
| Medical Support | Licensed physicians, unlimited check-ins | Licensed providers, SMS coaching, digital check-ins |
Prices reflect starting rates without insurance. Actual costs may vary by plan and medication. Last updated March 2026.
TrimRx: Detailed Look
TrimRx
Doctor-supervised GLP-1 weight loss with free shipping from $179/mo
Pros
- Free medical consultation with a licensed provider
- All-inclusive pricing — no hidden fees or surprise bills
- Free delivery and unlimited medical check-ins included
- No contracts — cancel or pause treatment anytime
Cons
- Compounded medications only — no brand-name options
- Available in select states, not all 50
Users who want affordable compounded GLP-1s with transparent, all-inclusive pricing
TMates: Detailed Look
TMates
GLP-1 weight loss program that accepts major insurance plans
Pros
- One of the few GLP-1 providers that accepts major insurance
- Flat-rate pricing includes meds, consults, coaching, and delivery
- 24/7 SMS-based coaching and digital check-ins
- Phentermine option for non-GLP-1 candidates
Cons
- Relatively newer platform with limited independent reviews
- Full program details require enrollment to verify
Users with insurance who want a coached GLP-1 program with multiple medication options
Which Should You Choose?
The right choice depends on your specific needs and priorities. Here is a quick decision framework:
Go with TrimRx at $179/month. Semaglutide from $199/mo, Tirzepatide from $299/mo.
TrimRx has the edge with a 8.4 rating.
TMates accepts insurance, which can significantly reduce your out-of-pocket cost.
Compare their support: TrimRx offers licensed physicians, unlimited check-ins, while TMates provides licensed providers, sms coaching, digital check-ins.
TMates at $199/month may offer features that justify the premium.
Frequently Asked Questions
Is TrimRx better than TMates?
TrimRx has a 8.4 rating while TMates has a 7.8 rating. The better choice depends on your priorities — TrimRx is best for users who want affordable compounded glp-1s with transparent, all-inclusive pricing, while TMates is best for users with insurance who want a coached glp-1 program with multiple medication options.
How much does TrimRx cost compared to TMates?
TrimRx starts at $179/month (semaglutide from $199/mo, tirzepatide from $299/mo), while TMates starts at $199/month ($199/mo semaglutide, $297/mo tirzepatide).
Do TrimRx and TMates accept insurance?
TrimRx does not accept insurance. TMates accepts insurance.
Which GLP-1 medications does TrimRx offer vs TMates?
TrimRx offers Compounded Semaglutide, Compounded Tirzepatide. TMates offers Compounded Semaglutide, Compounded Tirzepatide, Phentermine.
Can I cancel TrimRx or TMates at any time?
TrimRx allows cancel anytime. TMates also allows cancel anytime.
Are TrimRx and TMates available in my state?
TrimRx is available in 45 states. TMates is available in 45 states.