TrimRx vs Sesame Care: Which GLP-1 Program Is Better? (2026)
A detailed side-by-side comparison of TrimRx and Sesame Care to help you choose the right GLP-1 weight loss program based on pricing, medications, medical support, and more.
Quick Verdict
We recommend TrimRx
Between these two providers, TrimRx is our pick for most users. It offers a higher overall rating (9.3 vs 7.2), more affordable pricing. That said, Sesame Care may be the better fit if you are looking for users with insurance who want cheap doctor visits — medication costs are separate and not included.
TrimRx scores 9.3/10 in our independent evaluation at $179/month, while Sesame Care scores 7.2/10 at $225/month. Both programs include a licensed physician consultation and ship medication directly to your door. Our rating considers five factors: safety and medical oversight (30%), pricing transparency (25%), cost value (20%), clinical support quality (15%), and onboarding speed (10%). This comparison was independently produced — neither provider pays for placement or higher ratings. Prices verified April 2026.
Side-by-Side Comparison
| Feature | TrimRx | Sesame Care |
|---|---|---|
| Monthly Price | $179 | $225 |
| Rating | 9.3 / 10 | 7.2 / 10 |
| Medication Type | Compounded Only | Brand & Compounded |
| Insurance Accepted | No | Yes |
| States Available | 45 states | All 50 states |
| Consultation Fee | Free | $25-75 |
| Shipping | Free Shipping | Paid |
| Cancel Anytime | Yes | Yes |
| Medical Support | Licensed physicians, personalized consultations, unlimited check-ins | Licensed physicians, per-visit model |
Prices reflect starting rates without insurance. Actual costs may vary by plan and medication. Last updated April 2026.
TrimRx: Detailed Look
TrimRx
Personalized GLP-1 consultations with tailored prescriptions and ongoing physician support
Pros
- Personalized doctor consultations tailored to your health history
- All-inclusive pricing — no hidden fees or surprise bills
- Free delivery and unlimited medical check-ins included
- No contracts — cancel or pause treatment anytime
Cons
- Compounded medications only — no brand-name options
- Available in select states, not all 50
Users who want personalized doctor consultations with transparent all-inclusive pricing
Sesame Care: Detailed Look
Sesame Care
Affordable telehealth marketplace connecting patients with doctors from $25
Pros
- Lowest consultation cost — visits from just $25
- Prescribes brand-name FDA-approved medications
- Transparent per-visit pricing with no subscriptions
- Wide network of licensed physicians across all 50 states
Cons
- Medication cost is separate and not included in visit fee
- No compounded options — brand-name only (higher drug cost)
Users with insurance who want cheap doctor visits — medication costs are separate and not included
Which Should You Choose?
The right choice depends on your specific needs and priorities. Here is a quick decision framework:
Go with TrimRx at $179/month. Semaglutide from $199/mo, Tirzepatide from $299/mo. All-inclusive pricing..
TrimRx has the edge with a 9.3 rating.
Sesame Care accepts insurance, which can significantly reduce your out-of-pocket cost.
TrimRx focuses on compounded medications at a lower price point.
Compare their support: TrimRx offers licensed physicians, personalized consultations, unlimited check-ins, while Sesame Care provides licensed physicians, per-visit model.
Sesame Care at $225/month may offer features that justify the premium.
Frequently Asked Questions
Is TrimRx better than Sesame Care?
TrimRx has a 9.3 rating while Sesame Care has a 7.2 rating. The better choice depends on your priorities — TrimRx is best for users who want personalized doctor consultations with transparent all-inclusive pricing, while Sesame Care is best for users with insurance who want cheap doctor visits — medication costs are separate and not included.
How much does TrimRx cost compared to Sesame Care?
TrimRx starts at $179/month (semaglutide from $199/mo, tirzepatide from $299/mo. all-inclusive pricing.), while Sesame Care starts at $225/month ($25-75 per visit + medication at pharmacy prices ($200-1,400/mo). total starting cost ~$225/mo with insurance savings cards. medication not included in visit fee.).
Do TrimRx and Sesame Care accept insurance?
TrimRx does not accept insurance. Sesame Care accepts insurance.
Which GLP-1 medications does TrimRx offer vs Sesame Care?
TrimRx offers Compounded Semaglutide, Compounded Tirzepatide. Sesame Care offers Ozempic, Wegovy, Mounjaro, Zepbound, Rybelsus.
Can I cancel TrimRx or Sesame Care at any time?
TrimRx allows cancel anytime. Sesame Care also allows cancel anytime.
Are TrimRx and Sesame Care available in my state?
TrimRx is available in 45 states. Sesame Care is available in all 50 states.