TrimRx vs Sesame Care: Which GLP-1 Program Is Better? (2026)

A detailed side-by-side comparison of TrimRx and Sesame Care to help you choose the right GLP-1 weight loss program based on pricing, medications, medical support, and more.

By GLP-1 Watchdog Editorial TeamIndependent Health Research
Published: March 30, 2026|Updated: March 30, 2026

Quick Verdict

We recommend TrimRx

Between these two providers, TrimRx is our pick for most users. It offers a higher overall rating (8.4 vs 7.8). That said, Sesame Care may be the better fit if you are looking for users who want cheap doctor visits and already have insurance to cover brand-name medications.

Side-by-Side Comparison

FeatureTrimRxSesame Care
Monthly Price$179$25
Rating8.4 / 107.8 / 10
Medication TypeCompounded OnlyBrand & Compounded
Insurance AcceptedNoYes
States Available45 statesAll 50 states
Consultation FeeFree$25-75
ShippingFree ShippingPaid
Cancel AnytimeYesYes
Medical SupportLicensed physicians, unlimited check-insLicensed physicians, per-visit model

Prices reflect starting rates without insurance. Actual costs may vary by plan and medication. Last updated March 2026.

TrimRx: Detailed Look

TrimRx

Doctor-supervised GLP-1 weight loss with free shipping from $179/mo

8.4/10
Very Good

Pros

  • Free medical consultation with a licensed provider
  • All-inclusive pricing — no hidden fees or surprise bills
  • Free delivery and unlimited medical check-ins included
  • No contracts — cancel or pause treatment anytime

Cons

  • Compounded medications only — no brand-name options
  • Available in select states, not all 50
Best For

Users who want affordable compounded GLP-1s with transparent, all-inclusive pricing

Sesame Care: Detailed Look

Sesame Care

Affordable telehealth marketplace connecting patients with doctors from $25

7.8/10
Good

Pros

  • Lowest consultation cost — visits from just $25
  • Prescribes brand-name FDA-approved medications
  • Transparent per-visit pricing with no subscriptions
  • Wide network of licensed physicians across all 50 states

Cons

  • Medication cost is separate and not included in visit fee
  • No compounded options — brand-name only (higher drug cost)
Best For

Users who want cheap doctor visits and already have insurance to cover brand-name medications

Which Should You Choose?

The right choice depends on your specific needs and priorities. Here is a quick decision framework:

You want the lowest monthly cost

Go with Sesame Care at $25/month. $25-75 per visit; medication costs separate.

You want the highest-rated program

TrimRx has the edge with a 8.4 rating.

You have insurance coverage

Sesame Care accepts insurance, which can significantly reduce your out-of-pocket cost.

You want affordable compounded options

TrimRx focuses on compounded medications at a lower price point.

You want comprehensive medical support

Compare their support: TrimRx offers licensed physicians, unlimited check-ins, while Sesame Care provides licensed physicians, per-visit model.

You are willing to invest more for premium care

TrimRx at $179/month may offer features that justify the premium.

TrimRx

Starting at $179/mo · Very Good

Visit TrimRx

Sesame Care

Starting at $25/mo · Good

Visit Sesame Care

Frequently Asked Questions

Is TrimRx better than Sesame Care?

TrimRx has a 8.4 rating while Sesame Care has a 7.8 rating. The better choice depends on your priorities — TrimRx is best for users who want affordable compounded glp-1s with transparent, all-inclusive pricing, while Sesame Care is best for users who want cheap doctor visits and already have insurance to cover brand-name medications.

How much does TrimRx cost compared to Sesame Care?

TrimRx starts at $179/month (semaglutide from $199/mo, tirzepatide from $299/mo), while Sesame Care starts at $25/month ($25-75 per visit; medication costs separate).

Do TrimRx and Sesame Care accept insurance?

TrimRx does not accept insurance. Sesame Care accepts insurance.

Which GLP-1 medications does TrimRx offer vs Sesame Care?

TrimRx offers Compounded Semaglutide, Compounded Tirzepatide. Sesame Care offers Ozempic, Wegovy, Mounjaro, Zepbound, Rybelsus.

Can I cancel TrimRx or Sesame Care at any time?

TrimRx allows cancel anytime. Sesame Care also allows cancel anytime.

Are TrimRx and Sesame Care available in my state?

TrimRx is available in 45 states. Sesame Care is available in all 50 states.

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