ShedRx vs Yucca Health: Which GLP-1 Program Is Better? (2026)

A detailed side-by-side comparison of ShedRx and Yucca Health to help you choose the right GLP-1 weight loss program based on pricing, medications, medical support, and more.

Eduard Cristea
Eduard Cristea
Dr. A. Goher, MD
Medically reviewed by Dr. A. Goher, MD
Published:

Quick Verdict

We recommend Yucca Health

Between these two providers, Yucca Health is our pick for most users. It offers a higher overall rating (9.2 vs 8.8), more affordable pricing. That said, ShedRx may be the better fit if you are looking for users who want multiple medication delivery forms and a money-back weight loss guarantee.

Yucca Health scores 9.2/10 in our independent evaluation at $146/month, while ShedRx scores 8.8/10 at $199/month. Both programs include a licensed physician consultation and ship medication directly to your door. Our rating considers five factors: safety and medical oversight (30%), pricing transparency (25%), cost value (20%), clinical support quality (15%), and onboarding speed (10%). This comparison was independently produced — neither provider pays for placement or higher ratings. Prices verified April 2026.

Side-by-Side Comparison

FeatureShedRxYucca Health
Monthly Price$199$146
Rating8.8 / 109.2 / 10
Medication TypeBrand & CompoundedCompounded Only
Insurance AcceptedNoNo
States AvailableAll 50 statesAll 50 states
Consultation FeeIncludedFree
ShippingFree ShippingFree Shipping
Cancel AnytimeYesNo
Medical SupportLicensed physicians, health coaching, supplement guidanceLicensed U.S. physicians (Dr. Wasef, Dr. Sakla), provider-guided care, 24hr review

Prices reflect starting rates without insurance. Actual costs may vary by plan and medication. Last updated April 2026.

ShedRx: Detailed Look

ShedRx

150K+ members with 5 medication forms — injections, oral drops, lozenges, tablets, and pills

8.8/10
Very Good

Pros

  • Most delivery forms of any provider: injections, oral drops, lozenges, tablets, and pills
  • 10% weight loss guarantee within 9 months or full refund
  • Both compounded and brand-name options (Wegovy, Zepbound)
  • 150,000+ members, health coaching and supplements included

Cons

  • Price increases at higher doses (up to $299/mo)
  • Mixed customer service reviews — communication speed can lag
Best For

Users who want multiple medication delivery forms and a money-back weight loss guarantee

Yucca Health: Detailed Look

Yucca Health

LegitScript-certified GLP-1 provider with 4% conversion rate, named physicians, and BNPL financing

9.2/10
Excellent

Pros

  • LegitScript certified — pharmacy and telehealth verified
  • 4.6/5 Trustpilot rating from 1,000+ verified patient reviews
  • Named physicians: Dr. Michael Wasef, MD and Dr. Andrew Sakla, DO
  • Buy now, pay later via Klarna, Affirm, and Afterpay

Cons

  • Best pricing requires 6-month commitment
  • Compounded medications only — no brand-name options
Best For

Users who want a LegitScript-certified provider with verified patient reviews and flexible financing

Which Should You Choose?

The right choice depends on your specific needs and priorities. Here is a quick decision framework:

You want the lowest monthly cost

Go with Yucca Health at $146/month. $146/mo semaglutide on 6-month plan, $258/mo tirzepatide. Klarna/Affirm/Afterpay available..

You want the highest-rated program

Yucca Health has the edge with a 9.2 rating.

You want affordable compounded options

Yucca Health focuses on compounded medications at a lower price point.

You want comprehensive medical support

Compare their support: ShedRx offers licensed physicians, health coaching, supplement guidance, while Yucca Health provides licensed u.s. physicians (dr. wasef, dr. sakla), provider-guided care, 24hr review.

You are willing to invest more for premium care

ShedRx at $199/month may offer features that justify the premium.

ShedRx

Starting at $199/mo · Very Good

Visit ShedRx

Yucca Health

Starting at $146/mo · Excellent

Visit Yucca Health

Frequently Asked Questions

Is ShedRx better than Yucca Health?

ShedRx has a 8.8 rating while Yucca Health has a 9.2 rating. The better choice depends on your priorities — ShedRx is best for users who want multiple medication delivery forms and a money-back weight loss guarantee, while Yucca Health is best for users who want a legitscript-certified provider with verified patient reviews and flexible financing.

How much does ShedRx cost compared to Yucca Health?

ShedRx starts at $199/month ($199/mo semaglutide starting dose, up to $299/mo at higher doses. brand pathway $99/mo + pharmacy cost.), while Yucca Health starts at $146/month ($146/mo semaglutide on 6-month plan, $258/mo tirzepatide. klarna/affirm/afterpay available.).

Do ShedRx and Yucca Health accept insurance?

ShedRx does not accept insurance. Yucca Health does not accept insurance.

Which GLP-1 medications does ShedRx offer vs Yucca Health?

ShedRx offers Compounded Semaglutide, Compounded Tirzepatide, Wegovy, Zepbound. Yucca Health offers Compounded Semaglutide+, Compounded Tirzepatide+.

Can I cancel ShedRx or Yucca Health at any time?

ShedRx allows cancel anytime. Yucca Health may have cancellation restrictions.

Are ShedRx and Yucca Health available in my state?

ShedRx is available in all 50 states. Yucca Health is available in all 50 states.