ShedRx vs TrimRx: Which GLP-1 Program Is Better? (2026)
A detailed side-by-side comparison of ShedRx and TrimRx to help you choose the right GLP-1 weight loss program based on pricing, medications, medical support, and more.
Quick Verdict
We recommend ShedRx
Between these two providers, ShedRx is our pick for most users. It offers a higher overall rating (8.8 vs 6.6), availability in all 50 states, both brand-name and compounded medication options. That said, TrimRx may be the better fit if you are looking for users who want affordable compounded glp-1s with transparent, all-inclusive pricing.
ShedRx scores 8.8/10 in our independent evaluation at $199/month, while TrimRx scores 6.6/10 at $179/month. Both programs include a licensed physician consultation and ship medication directly to your door. ShedRx also offers oral GLP-1 options for patients who prefer pills over injections. Our rating considers five factors: safety and medical oversight (30%), pricing transparency (25%), cost value (20%), clinical support quality (15%), and onboarding speed (10%). This comparison was independently produced — neither provider pays for placement or higher ratings. Prices verified April 2026.
Side-by-Side Comparison
| Feature | ShedRx | TrimRx |
|---|---|---|
| Monthly Price | $199 | $179 |
| Rating | 8.8 / 10 | 6.6 / 10 |
| Medication Type | Brand & Compounded | Compounded Only |
| Insurance Accepted | No | No |
| States Available | All 50 states | 45 states |
| Consultation Fee | Included | Free |
| Shipping | Free Shipping | Free Shipping |
| Cancel Anytime | Yes | Yes |
| Medical Support | Licensed physicians, health coaching, supplement guidance | Licensed physicians, unlimited check-ins |
Prices reflect starting rates without insurance. Actual costs may vary by plan and medication. Last updated April 2026.
ShedRx: Detailed Look
ShedRx
150K+ members with 5 medication forms — injections, oral drops, lozenges, tablets, and pills
Pros
- Most delivery forms of any provider: injections, oral drops, lozenges, tablets, and pills
- 10% weight loss guarantee within 9 months or full refund
- Both compounded and brand-name options (Wegovy, Zepbound)
- 150,000+ members, health coaching and supplements included
Cons
- Price increases at higher doses (up to $299/mo)
- Mixed customer service reviews — communication speed can lag
Users who want multiple medication delivery forms and a money-back weight loss guarantee
TrimRx: Detailed Look
TrimRx
Doctor-supervised GLP-1 weight loss with free shipping from $179/mo
Pros
- Free medical consultation with a licensed provider
- All-inclusive pricing — no hidden fees or surprise bills
- Free delivery and unlimited medical check-ins included
- No contracts — cancel or pause treatment anytime
Cons
- Compounded medications only — no brand-name options
- Available in select states, not all 50
Users who want affordable compounded GLP-1s with transparent, all-inclusive pricing
Which Should You Choose?
The right choice depends on your specific needs and priorities. Here is a quick decision framework:
Go with TrimRx at $179/month. Semaglutide from $199/mo, Tirzepatide from $299/mo.
ShedRx has the edge with a 8.8 rating.
TrimRx focuses on compounded medications at a lower price point.
Compare their support: ShedRx offers licensed physicians, health coaching, supplement guidance, while TrimRx provides licensed physicians, unlimited check-ins.
ShedRx at $199/month may offer features that justify the premium.
Frequently Asked Questions
Is ShedRx better than TrimRx?
ShedRx has a 8.8 rating while TrimRx has a 6.6 rating. The better choice depends on your priorities — ShedRx is best for users who want multiple medication delivery forms and a money-back weight loss guarantee, while TrimRx is best for users who want affordable compounded glp-1s with transparent, all-inclusive pricing.
How much does ShedRx cost compared to TrimRx?
ShedRx starts at $199/month ($199/mo semaglutide starting dose, up to $299/mo at higher doses. brand pathway $99/mo + pharmacy cost.), while TrimRx starts at $179/month (semaglutide from $199/mo, tirzepatide from $299/mo).
Do ShedRx and TrimRx accept insurance?
ShedRx does not accept insurance. TrimRx does not accept insurance.
Which GLP-1 medications does ShedRx offer vs TrimRx?
ShedRx offers Compounded Semaglutide, Compounded Tirzepatide, Wegovy, Zepbound. TrimRx offers Compounded Semaglutide, Compounded Tirzepatide.
Can I cancel ShedRx or TrimRx at any time?
ShedRx allows cancel anytime. TrimRx also allows cancel anytime.
Are ShedRx and TrimRx available in my state?
ShedRx is available in all 50 states. TrimRx is available in 45 states.