ShedRx vs SkinnyRx: Which GLP-1 Program Is Better? (2026)
A detailed side-by-side comparison of ShedRx and SkinnyRx to help you choose the right GLP-1 weight loss program based on pricing, medications, medical support, and more.
Quick Verdict
We recommend SkinnyRx
Between these two providers, SkinnyRx is our pick for most users. It offers a higher overall rating (9.1 vs 8.8). That said, ShedRx may be the better fit if you are looking for users who want multiple medication delivery forms and a money-back weight loss guarantee.
SkinnyRx scores 9.1/10 in our independent evaluation at $199/month, while ShedRx scores 8.8/10 at $199/month. Both programs include a licensed physician consultation and ship medication directly to your door. SkinnyRx also offers oral GLP-1 options for patients who prefer pills over injections. Our rating considers five factors: safety and medical oversight (30%), pricing transparency (25%), cost value (20%), clinical support quality (15%), and onboarding speed (10%). This comparison was independently produced — neither provider pays for placement or higher ratings. Prices verified April 2026.
Side-by-Side Comparison
| Feature | ShedRx | SkinnyRx |
|---|---|---|
| Monthly Price | $199 | $199 |
| Rating | 8.8 / 10 | 9.1 / 10 |
| Medication Type | Brand & Compounded | Compounded Only |
| Insurance Accepted | No | No |
| States Available | All 50 states | 48 states |
| Consultation Fee | Included | Included |
| Shipping | Free Shipping | Free Shipping |
| Cancel Anytime | Yes | Yes |
| Medical Support | Licensed physicians, health coaching, supplement guidance | Licensed U.S. physicians, 24-48hr prescription review |
Prices reflect starting rates without insurance. Actual costs may vary by plan and medication. Last updated April 2026.
ShedRx: Detailed Look
ShedRx
150K+ members with 5 medication forms — injections, oral drops, lozenges, tablets, and pills
Pros
- Most delivery forms of any provider: injections, oral drops, lozenges, tablets, and pills
- 10% weight loss guarantee within 9 months or full refund
- Both compounded and brand-name options (Wegovy, Zepbound)
- 150,000+ members, health coaching and supplements included
Cons
- Price increases at higher doses (up to $299/mo)
- Mixed customer service reviews — communication speed can lag
Users who want multiple medication delivery forms and a money-back weight loss guarantee
SkinnyRx: Detailed Look
SkinnyRx
Fastest-growing GLP-1 provider — oral, sublingual, and injectable options with Affirm financing
Pros
- Three delivery forms: injectable, sublingual, and oral tablets
- Free overnight shipping from FDA-regulated U.S. pharmacies
- Month-to-month billing with no contracts
- 4.8/5 Trustpilot rating from thousands of verified reviews
Cons
- Cash-pay only — no insurance billing
- Compounded medications only — no brand-name options
Users who want multiple delivery forms (oral, sublingual, injectable) for their GLP-1
Which Should You Choose?
The right choice depends on your specific needs and priorities. Here is a quick decision framework:
Go with ShedRx at $199/month. $199/mo semaglutide starting dose, up to $299/mo at higher doses. Brand pathway $99/mo + pharmacy cost..
SkinnyRx has the edge with a 9.1 rating.
SkinnyRx focuses on compounded medications at a lower price point.
Compare their support: ShedRx offers licensed physicians, health coaching, supplement guidance, while SkinnyRx provides licensed u.s. physicians, 24-48hr prescription review.
Frequently Asked Questions
Is ShedRx better than SkinnyRx?
ShedRx has a 8.8 rating while SkinnyRx has a 9.1 rating. The better choice depends on your priorities — ShedRx is best for users who want multiple medication delivery forms and a money-back weight loss guarantee, while SkinnyRx is best for users who want multiple delivery forms (oral, sublingual, injectable) for their glp-1.
How much does ShedRx cost compared to SkinnyRx?
ShedRx starts at $199/month ($199/mo semaglutide starting dose, up to $299/mo at higher doses. brand pathway $99/mo + pharmacy cost.), while SkinnyRx starts at $199/month ($199/mo semaglutide, up to $349/mo for tirzepatide).
Do ShedRx and SkinnyRx accept insurance?
ShedRx does not accept insurance. SkinnyRx does not accept insurance.
Which GLP-1 medications does ShedRx offer vs SkinnyRx?
ShedRx offers Compounded Semaglutide, Compounded Tirzepatide, Wegovy, Zepbound. SkinnyRx offers Compounded Semaglutide (Injectable), Compounded Semaglutide (Sublingual), Compounded Tirzepatide (Injectable), Compounded Tirzepatide (Tablets).
Can I cancel ShedRx or SkinnyRx at any time?
ShedRx allows cancel anytime. SkinnyRx also allows cancel anytime.
Are ShedRx and SkinnyRx available in my state?
ShedRx is available in all 50 states. SkinnyRx is available in 48 states.