PeterMD vs SynergyRx: Which GLP-1 Program Is Better? (2026)

A detailed side-by-side comparison of PeterMD and SynergyRx to help you choose the right GLP-1 weight loss program based on pricing, medications, medical support, and more.

By GLP-1 Watchdog Editorial TeamIndependent Health Research
Published: March 30, 2026|Updated: March 30, 2026

Quick Verdict

We recommend SynergyRx

Between these two providers, SynergyRx is our pick for most users. It offers a higher overall rating (7.6 vs 7.5), both brand-name and compounded medication options. That said, PeterMD may be the better fit if you are looking for budget-conscious users looking for the lowest monthly glp-1 cost.

Side-by-Side Comparison

FeaturePeterMDSynergyRx
Monthly Price$105$200
Rating7.5 / 107.6 / 10
Medication TypeCompounded OnlyBrand & Compounded
Insurance AcceptedNoNo
States Available46 states45 states
Consultation FeeFreeIncluded
ShippingFree ShippingFree Shipping
Cancel AnytimeYesYes
Medical SupportLicensed physicians, virtual screeningLicensed providers, 24/7 messaging, unlimited check-ins

Prices reflect starting rates without insurance. Actual costs may vary by plan and medication. Last updated March 2026.

PeterMD: Detailed Look

PeterMD

Among the lowest-cost GLP-1 programs starting at $105/month

7.5/10
Good

Pros

  • Among the lowest starting prices at ~$105/month
  • Free consultations, shipping, and supplies included
  • Nearly 14,000 Trustpilot reviews averaging 4.8 stars
  • Fast virtual screening and medication delivery

Cons

  • Mixed post-purchase customer service (some billing complaints)
  • Blood work not available in AL, ID, NY, NJ
Best For

Budget-conscious users looking for the lowest monthly GLP-1 cost

SynergyRx: Detailed Look

SynergyRx

Bundled GLP-1 programs with 24/7 support and no hidden fees

7.6/10
Good

Pros

  • All-inclusive bundled pricing — no fees for messaging or adjustments
  • Free expedited shipping on all orders
  • 24/7 support access with unlimited messaging
  • Partners with multiple certified pharmacies for reliability

Cons

  • Starting price of $200/mo is mid-range for compounded semaglutide
  • May not be available in all 50 states
Best For

Users who want predictable bundled pricing with 24/7 support access

Which Should You Choose?

The right choice depends on your specific needs and priorities. Here is a quick decision framework:

You want the lowest monthly cost

Go with PeterMD at $105/month. Semaglutide + B12 subscription, tirzepatide also available.

You want the highest-rated program

SynergyRx has the edge with a 7.6 rating.

You want affordable compounded options

PeterMD focuses on compounded medications at a lower price point.

You want comprehensive medical support

Compare their support: PeterMD offers licensed physicians, virtual screening, while SynergyRx provides licensed providers, 24/7 messaging, unlimited check-ins.

You are willing to invest more for premium care

SynergyRx at $200/month may offer features that justify the premium.

PeterMD

Starting at $105/mo · Good

Visit PeterMD

SynergyRx

Starting at $200/mo · Good

Visit SynergyRx

Frequently Asked Questions

Is PeterMD better than SynergyRx?

PeterMD has a 7.5 rating while SynergyRx has a 7.6 rating. The better choice depends on your priorities — PeterMD is best for budget-conscious users looking for the lowest monthly glp-1 cost, while SynergyRx is best for users who want predictable bundled pricing with 24/7 support access.

How much does PeterMD cost compared to SynergyRx?

PeterMD starts at $105/month (semaglutide + b12 subscription, tirzepatide also available), while SynergyRx starts at $200/month ($200/mo semaglutide, $299-347/mo tirzepatide).

Do PeterMD and SynergyRx accept insurance?

PeterMD does not accept insurance. SynergyRx does not accept insurance.

Which GLP-1 medications does PeterMD offer vs SynergyRx?

PeterMD offers Compounded Semaglutide + B12, Compounded Tirzepatide. SynergyRx offers Compounded Semaglutide, Compounded Tirzepatide, Ozempic, Wegovy, Mounjaro.

Can I cancel PeterMD or SynergyRx at any time?

PeterMD allows cancel anytime. SynergyRx also allows cancel anytime.

Are PeterMD and SynergyRx available in my state?

PeterMD is available in 46 states. SynergyRx is available in 45 states.

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