Oak Longevity vs Enhance MD: Which GLP-1 Program Is Better? (2026)

A detailed side-by-side comparison of Oak Longevity and Enhance MD to help you choose the right GLP-1 weight loss program based on pricing, medications, medical support, and more.

Eduard Cristea
Eduard Cristea
Dr. A. Goher, MD
Medically reviewed by Dr. A. Goher, MD
Published: |Updated:

Quick Verdict

We recommend Oak Longevity

Between these two providers, Oak Longevity is our pick for most users. It offers a higher overall rating (9 vs 8.3), more affordable pricing. That said, Enhance MD may be the better fit if you are looking for budget-conscious users interested in combination therapies.

Side-by-Side Comparison

FeatureOak LongevityEnhance MD
Monthly Price$130$249
Rating9 / 108.3 / 10
Medication TypeCompounded OnlyBrand & Compounded
Insurance AcceptedNoNo
States AvailableAll 50 statesAll 50 states
Consultation FeeIncludedIncluded
ShippingFree ShippingFree Shipping
Cancel AnytimeYesYes
Medical SupportBoard-certified physicians, free health coaching, responsive care teamBoard-certified physicians

Prices reflect starting rates without insurance. Actual costs may vary by plan and medication. Last updated April 2026.

Oak Longevity: Detailed Look

Oak Longevity

Affordable GLP-1 from $130/mo — semaglutide and tirzepatide with free shipping and health coaching

9/10
Excellent

Pros

  • Among the cheapest: semaglutide from $130/mo, tirzepatide from $199/mo
  • Free shipping + free health coaching included
  • No subscriptions or membership fees — pay monthly
  • Same-day approval with 10,000+ satisfied patients

Cons

  • Compounded medications only — no brand-name options
  • Newer platform with limited independent reviews
Best For

Budget-conscious users who want the lowest price with health coaching and no membership fees

Enhance MD: Detailed Look

Enhance MD

Physician-led weight management with NAD+ options

8.3/10
Good

Pros

  • Affordable entry point starting at $115/month
  • Unique NAD+ therapy option alongside GLP-1
  • Board-certified physicians lead all protocols

Cons

  • NAD+ weight loss claims lack strong clinical evidence
  • Less transparent about which medications are compounded vs brand
Best For

Budget-conscious users interested in combination therapies

Which Should You Choose?

The right choice depends on your specific needs and priorities. Here is a quick decision framework:

You want the lowest monthly cost

Go with Oak Longevity at $130/month. $130/mo semaglutide, $199/mo tirzepatide. Use code OAKNEW50 for $50 off first month. All dosages same price..

You want the highest-rated program

Oak Longevity has the edge with a 9 rating.

You want affordable compounded options

Oak Longevity focuses on compounded medications at a lower price point.

You want comprehensive medical support

Compare their support: Oak Longevity offers board-certified physicians, free health coaching, responsive care team, while Enhance MD provides board-certified physicians.

You are willing to invest more for premium care

Enhance MD at $249/month may offer features that justify the premium.

Oak Longevity

Starting at $130/mo · Excellent

Visit Oak Longevity

Enhance MD

Starting at $249/mo · Good

Visit Enhance MD

Frequently Asked Questions

Is Oak Longevity better than Enhance MD?

Oak Longevity has a 9 rating while Enhance MD has a 8.3 rating. The better choice depends on your priorities — Oak Longevity is best for budget-conscious users who want the lowest price with health coaching and no membership fees, while Enhance MD is best for budget-conscious users interested in combination therapies.

How much does Oak Longevity cost compared to Enhance MD?

Oak Longevity starts at $130/month ($130/mo semaglutide, $199/mo tirzepatide. use code oaknew50 for $50 off first month. all dosages same price.), while Enhance MD starts at $249/month (semaglutide $249/mo; tirzepatide $379/mo; annual plans save ~15%).

Do Oak Longevity and Enhance MD accept insurance?

Oak Longevity does not accept insurance. Enhance MD does not accept insurance.

Which GLP-1 medications does Oak Longevity offer vs Enhance MD?

Oak Longevity offers Compounded Semaglutide, Compounded Tirzepatide. Enhance MD offers Semaglutide, Tirzepatide, NAD+.

Can I cancel Oak Longevity or Enhance MD at any time?

Oak Longevity allows cancel anytime. Enhance MD also allows cancel anytime.

Are Oak Longevity and Enhance MD available in my state?

Oak Longevity is available in all 50 states. Enhance MD is available in all 50 states.