Novi vs SynergyRx: Which GLP-1 Program Is Better? (2026)
A detailed side-by-side comparison of Novi and SynergyRx to help you choose the right GLP-1 weight loss program based on pricing, medications, medical support, and more.
Quick Verdict
We recommend SynergyRx
Between these two providers, SynergyRx is our pick for most users. It offers a higher overall rating (7.6 vs 7.3). That said, Novi may be the better fit if you are looking for users who want flexible, no-contract glp-1 access with strong clinical support.
Side-by-Side Comparison
| Feature | Novi | SynergyRx |
|---|---|---|
| Monthly Price | $199 | $200 |
| Rating | 7.3 / 10 | 7.6 / 10 |
| Medication Type | Brand & Compounded | Brand & Compounded |
| Insurance Accepted | No | No |
| States Available | 45 states | 45 states |
| Consultation Fee | Included | Included |
| Shipping | Free Shipping | Free Shipping |
| Cancel Anytime | Yes | Yes |
| Medical Support | Licensed physicians, unlimited access, nutritionist meal plans | Licensed providers, 24/7 messaging, unlimited check-ins |
Prices reflect starting rates without insurance. Actual costs may vary by plan and medication. Last updated March 2026.
Novi: Detailed Look
Novi
No-contract GLP-1 access with unlimited clinician support from $199/mo
Pros
- All-in transparent pricing with no hidden fees
- Unlimited clinician access for check-ins and dose adjustments
- Month-to-month with no contracts or minimum commitments
- Includes nutritionist-crafted meal plans and online community
Cons
- No refunds once a prescription has been shipped
- Relatively new with limited long-term track record
Users who want flexible, no-contract GLP-1 access with strong clinical support
SynergyRx: Detailed Look
SynergyRx
Bundled GLP-1 programs with 24/7 support and no hidden fees
Pros
- All-inclusive bundled pricing — no fees for messaging or adjustments
- Free expedited shipping on all orders
- 24/7 support access with unlimited messaging
- Partners with multiple certified pharmacies for reliability
Cons
- Starting price of $200/mo is mid-range for compounded semaglutide
- May not be available in all 50 states
Users who want predictable bundled pricing with 24/7 support access
Which Should You Choose?
The right choice depends on your specific needs and priorities. Here is a quick decision framework:
Go with Novi at $199/month. $199/mo first month, no contract.
SynergyRx has the edge with a 7.6 rating.
Compare their support: Novi offers licensed physicians, unlimited access, nutritionist meal plans, while SynergyRx provides licensed providers, 24/7 messaging, unlimited check-ins.
SynergyRx at $200/month may offer features that justify the premium.
Frequently Asked Questions
Is Novi better than SynergyRx?
Novi has a 7.3 rating while SynergyRx has a 7.6 rating. The better choice depends on your priorities — Novi is best for users who want flexible, no-contract glp-1 access with strong clinical support, while SynergyRx is best for users who want predictable bundled pricing with 24/7 support access.
How much does Novi cost compared to SynergyRx?
Novi starts at $199/month ($199/mo first month, no contract), while SynergyRx starts at $200/month ($200/mo semaglutide, $299-347/mo tirzepatide).
Do Novi and SynergyRx accept insurance?
Novi does not accept insurance. SynergyRx does not accept insurance.
Which GLP-1 medications does Novi offer vs SynergyRx?
Novi offers Compounded Semaglutide, Brand-name GLP-1s. SynergyRx offers Compounded Semaglutide, Compounded Tirzepatide, Ozempic, Wegovy, Mounjaro.
Can I cancel Novi or SynergyRx at any time?
Novi allows cancel anytime. SynergyRx also allows cancel anytime.
Are Novi and SynergyRx available in my state?
Novi is available in 45 states. SynergyRx is available in 45 states.