TMates vs MyStart Health: Which GLP-1 Program Is Better? (2026)
A detailed side-by-side comparison of TMates and MyStart Health to help you choose the right GLP-1 weight loss program based on pricing, medications, medical support, and more.
Quick Verdict
We recommend MyStart Health
Between these two providers, MyStart Health is our pick for most users. It offers a higher overall rating (8.5 vs 7.8), availability in all 50 states, both brand-name and compounded medication options. That said, TMates may be the better fit if you are looking for users with insurance who want a coached glp-1 program with multiple medication options.
MyStart Health scores 8.5/10 in our independent evaluation at $224/month, while TMates scores 7.8/10 at $199/month. Both programs include a licensed physician consultation and ship medication directly to your door. Our rating considers five factors: safety and medical oversight (30%), pricing transparency (25%), cost value (20%), clinical support quality (15%), and onboarding speed (10%). This comparison was independently produced — neither provider pays for placement or higher ratings. Prices verified April 2026.
Side-by-Side Comparison
| Feature | TMates | MyStart Health |
|---|---|---|
| Monthly Price | $199 | $224 |
| Rating | 7.8 / 10 | 8.5 / 10 |
| Medication Type | Compounded Only | Brand & Compounded |
| Insurance Accepted | Yes | No |
| States Available | 45 states | All 50 states |
| Consultation Fee | Included | Free |
| Shipping | Free Shipping | Free Shipping |
| Cancel Anytime | Yes | Yes |
| Medical Support | Licensed providers, SMS coaching, digital check-ins | Licensed U.S. physicians, unlimited clinician access |
Prices reflect starting rates without insurance. Actual costs may vary by plan and medication. Last updated April 2026.
TMates: Detailed Look
TMates
GLP-1 weight loss program that accepts major insurance plans
Pros
- One of the few GLP-1 providers that accepts major insurance
- Flat-rate pricing includes meds, consults, coaching, and delivery
- 24/7 SMS-based coaching and digital check-ins
- Phentermine option for non-GLP-1 candidates
Cons
- Relatively newer platform with limited independent reviews
- Full program details require enrollment to verify
Users with insurance who want a coached GLP-1 program with multiple medication options
MyStart Health: Detailed Look
MyStart Health
GLP-1 programs with a price-lock guarantee and weight-loss promise
Pros
- Price Lock Guarantee — your rate never increases with dosage
- 10% bodyweight loss in 4 months or money back
- All-inclusive pricing with free shipping and labs
- Available in all 50 states with 24-hour consultation turnaround
Cons
- Some reports of shipping and fulfillment delays
- Tirzepatide option is significantly more expensive at $429/month
Users who value a money-back weight-loss guarantee and price-lock protection
Which Should You Choose?
The right choice depends on your specific needs and priorities. Here is a quick decision framework:
Go with TMates at $199/month. $199/mo semaglutide, $297/mo tirzepatide.
MyStart Health has the edge with a 8.5 rating.
TMates accepts insurance, which can significantly reduce your out-of-pocket cost.
TMates focuses on compounded medications at a lower price point.
Compare their support: TMates offers licensed providers, sms coaching, digital check-ins, while MyStart Health provides licensed u.s. physicians, unlimited clinician access.
MyStart Health at $224/month may offer features that justify the premium.
Frequently Asked Questions
Is TMates better than MyStart Health?
TMates has a 7.8 rating while MyStart Health has a 8.5 rating. The better choice depends on your priorities — TMates is best for users with insurance who want a coached glp-1 program with multiple medication options, while MyStart Health is best for users who value a money-back weight-loss guarantee and price-lock protection.
How much does TMates cost compared to MyStart Health?
TMates starts at $199/month ($199/mo semaglutide, $297/mo tirzepatide), while MyStart Health starts at $224/month ($299/mo (use code selflove25 for 25% off = $224/mo). includes meds, labs, shipping, unlimited clinician access).
Do TMates and MyStart Health accept insurance?
TMates accepts insurance. MyStart Health does not accept insurance.
Which GLP-1 medications does TMates offer vs MyStart Health?
TMates offers Compounded Semaglutide, Compounded Tirzepatide, Phentermine. MyStart Health offers Compounded Semaglutide, Compounded Tirzepatide, Ozempic, Wegovy.
Can I cancel TMates or MyStart Health at any time?
TMates allows cancel anytime. MyStart Health also allows cancel anytime.
Are TMates and MyStart Health available in my state?
TMates is available in 45 states. MyStart Health is available in all 50 states.
Not sure TMates or MyStart Health is right for you?
Answer 6 questions and we'll match you with the best program for your budget and goals.