MyStart Health vs TMates: Which GLP-1 Program Is Better? (2026)
A detailed side-by-side comparison of MyStart Health and TMates to help you choose the right GLP-1 weight loss program based on pricing, medications, medical support, and more.
Quick Verdict
We recommend MyStart Health
Between these two providers, MyStart Health is our pick for most users. It offers a higher overall rating (8 vs 7.8), more affordable pricing, availability in all 50 states, both brand-name and compounded medication options. That said, TMates may be the better fit if you are looking for users with insurance who want a coached glp-1 program with multiple medication options.
Side-by-Side Comparison
| Feature | MyStart Health | TMates |
|---|---|---|
| Monthly Price | $179 | $199 |
| Rating | 8 / 10 | 7.8 / 10 |
| Medication Type | Brand & Compounded | Compounded Only |
| Insurance Accepted | No | Yes |
| States Available | All 50 states | 45 states |
| Consultation Fee | Free | Included |
| Shipping | Free Shipping | Free Shipping |
| Cancel Anytime | Yes | Yes |
| Medical Support | Licensed U.S. physicians, unlimited clinician access | Licensed providers, SMS coaching, digital check-ins |
Prices reflect starting rates without insurance. Actual costs may vary by plan and medication. Last updated March 2026.
MyStart Health: Detailed Look
MyStart Health
GLP-1 programs with a price-lock guarantee and weight-loss promise
Pros
- Price Lock Guarantee — your rate never increases with dosage
- 10% bodyweight loss in 4 months or money back
- All-inclusive pricing with free shipping and labs
- Available in all 50 states with 24-hour consultation turnaround
Cons
- Some reports of shipping and fulfillment delays
- Tirzepatide option is significantly more expensive at $429/month
Users who value a money-back weight-loss guarantee and price-lock protection
TMates: Detailed Look
TMates
GLP-1 weight loss program that accepts major insurance plans
Pros
- One of the few GLP-1 providers that accepts major insurance
- Flat-rate pricing includes meds, consults, coaching, and delivery
- 24/7 SMS-based coaching and digital check-ins
- Phentermine option for non-GLP-1 candidates
Cons
- Relatively newer platform with limited independent reviews
- Full program details require enrollment to verify
Users with insurance who want a coached GLP-1 program with multiple medication options
Which Should You Choose?
The right choice depends on your specific needs and priorities. Here is a quick decision framework:
Go with MyStart Health at $179/month. $249/mo semaglutide, $429/mo tirzepatide.
MyStart Health has the edge with a 8 rating.
TMates accepts insurance, which can significantly reduce your out-of-pocket cost.
TMates focuses on compounded medications at a lower price point.
Compare their support: MyStart Health offers licensed u.s. physicians, unlimited clinician access, while TMates provides licensed providers, sms coaching, digital check-ins.
TMates at $199/month may offer features that justify the premium.
Frequently Asked Questions
Is MyStart Health better than TMates?
MyStart Health has a 8 rating while TMates has a 7.8 rating. The better choice depends on your priorities — MyStart Health is best for users who value a money-back weight-loss guarantee and price-lock protection, while TMates is best for users with insurance who want a coached glp-1 program with multiple medication options.
How much does MyStart Health cost compared to TMates?
MyStart Health starts at $179/month ($249/mo semaglutide, $429/mo tirzepatide), while TMates starts at $199/month ($199/mo semaglutide, $297/mo tirzepatide).
Do MyStart Health and TMates accept insurance?
MyStart Health does not accept insurance. TMates accepts insurance.
Which GLP-1 medications does MyStart Health offer vs TMates?
MyStart Health offers Compounded Semaglutide, Compounded Tirzepatide, Ozempic, Wegovy. TMates offers Compounded Semaglutide, Compounded Tirzepatide, Phentermine.
Can I cancel MyStart Health or TMates at any time?
MyStart Health allows cancel anytime. TMates also allows cancel anytime.
Are MyStart Health and TMates available in my state?
MyStart Health is available in all 50 states. TMates is available in 45 states.