ShedRx vs MyStart Health: Which GLP-1 Program Is Better? (2026)

A detailed side-by-side comparison of ShedRx and MyStart Health to help you choose the right GLP-1 weight loss program based on pricing, medications, medical support, and more.

Eduard Cristea
Eduard Cristea
Dr. A. Goher, MD
Medically reviewed by Dr. A. Goher, MD
Published:

Quick Verdict

We recommend ShedRx

Between these two providers, ShedRx is our pick for most users. It offers a higher overall rating (8.8 vs 8.5), more affordable pricing. That said, MyStart Health may be the better fit if you are looking for users who value a money-back weight-loss guarantee and price-lock protection.

ShedRx scores 8.8/10 in our independent evaluation at $159/month, while MyStart Health scores 8.5/10 at $224/month. Both programs include a licensed physician consultation and ship medication directly to your door. ShedRx also offers oral GLP-1 options for patients who prefer pills over injections. Our rating considers five factors: safety and medical oversight (30%), pricing transparency (25%), cost value (20%), clinical support quality (15%), and onboarding speed (10%). We earn affiliate commissions from some providers, disclosed on this page; no provider can pay to fake safety, licensing, or hide the downsides. Prices verified April 2026.

Side-by-Side Comparison

Monthly Price
ShedRx
MyStart Health
Rating
ShedRx
8.8 / 10
MyStart Health
8.5 / 10
Medication Type
ShedRx
Brand & Compounded
MyStart Health
Brand & Compounded
Insurance Accepted
ShedRx
No
MyStart Health
No
States Available
ShedRx
All 50 states
MyStart Health
All 50 states
Consultation Fee
ShedRx
Included
MyStart Health
Free
Shipping
ShedRx
Free Shipping
MyStart Health
Free Shipping
Cancel Anytime
ShedRx
No
MyStart Health
Yes
Medical Support
ShedRx
Licensed physicians, health coaching, supplement guidance
MyStart Health
Licensed U.S. physicians, unlimited clinician access

Prices reflect starting rates without insurance. Actual costs may vary by plan and medication. Last updated April 2026.

ShedRx: Detailed Look

ShedRx

150K+ members with 5 medication forms — injections, oral drops, lozenges, tablets, and pills

8.8/10
Very Good

Pros

  • Most delivery forms of any provider: injections, oral drops, lozenges, tablets, and pills
  • 120-day guarantee: lose 5% (or reach your goal weight) or your money back — first-time GLP-1 users, coaching and check-in conditions apply
  • Both compounded and brand-name options (Wegovy, Zepbound)
  • 150,000+ members, health coaching and supplements included

Cons

  • 2-month minimum on every plan; the $159 rate needs a 12-month commitment ($199 month-to-month)
  • Recurring Trustpilot complaints about cancellations, reaching support and unexpected charges
Best For

Users who want multiple medication delivery forms and a money-back weight loss guarantee

MyStart Health: Detailed Look

MyStart Health

GLP-1 programs with a price-lock guarantee and weight-loss promise

8.5/10
Excellent

Pros

  • Price Lock Guarantee — your rate never increases with dosage
  • 10% bodyweight loss in 4 months or money back
  • All-inclusive pricing with free shipping and labs
  • Available in all 50 states with 24-hour consultation turnaround

Cons

  • Some reports of shipping and fulfillment delays
  • Tirzepatide option is significantly more expensive at $429/month
Best For

Users who value a money-back weight-loss guarantee and price-lock protection

Which Should You Choose?

The right choice depends on your specific needs and priorities. Here is a quick decision framework:

You want the lowest monthly cost

Go with ShedRx at $159/month. Now trading as Shed (tryshed.com). Compounded semaglutide from $159/mo (12-month plan; $179 6-month, $199 monthly) and tirzepatide from $239/mo ($269 / $299). Oral options: lozenges from $199, liquid drops from $229, semaglutide tablets from $299. Brand pathway: Wegovy pill $149 / pen $199, Zepbound $349, Foundayo $149 — medication only, plus a $125/mo Shed membership. Every plan carries a 2-month minimum..

You want the highest-rated program

ShedRx has the edge with a 8.8 rating.

You want comprehensive medical support

Compare their support: ShedRx offers licensed physicians, health coaching, supplement guidance, while MyStart Health provides licensed u.s. physicians, unlimited clinician access.

You are willing to invest more for premium care

MyStart Health at $224/month may offer features that justify the premium.

ShedRx

Starting at $159/mo · Very Good

Visit ShedRx

MyStart Health

Starting at $224/mo · Excellent

Read MyStart Health Review

Frequently Asked Questions

Is ShedRx better than MyStart Health?

ShedRx has a 8.8 rating while MyStart Health has a 8.5 rating. The better choice depends on your priorities — ShedRx is best for users who want multiple medication delivery forms and a money-back weight loss guarantee, while MyStart Health is best for users who value a money-back weight-loss guarantee and price-lock protection.

How much does ShedRx cost compared to MyStart Health?

ShedRx starts at $159/month (now trading as shed (tryshed.com). compounded semaglutide from $159/mo (12-month plan; $179 6-month, $199 monthly) and tirzepatide from $239/mo ($269 / $299). oral options: lozenges from $199, liquid drops from $229, semaglutide tablets from $299. brand pathway: wegovy pill $149 / pen $199, zepbound $349, foundayo $149 — medication only, plus a $125/mo shed membership. every plan carries a 2-month minimum.), while MyStart Health starts at $224/month ($299/mo (use code selflove25 for 25% off = $224/mo). includes meds, labs, shipping, unlimited clinician access).

Do ShedRx and MyStart Health accept insurance?

ShedRx does not accept insurance. MyStart Health does not accept insurance.

Which GLP-1 medications does ShedRx offer vs MyStart Health?

ShedRx offers Compounded Semaglutide, Compounded Tirzepatide, Wegovy, Zepbound, Foundayo (oral orforglipron). MyStart Health offers Compounded Semaglutide, Compounded Tirzepatide, Ozempic, Wegovy.

Can I cancel ShedRx or MyStart Health at any time?

ShedRx may have cancellation restrictions. MyStart Health also allows cancel anytime.

Are ShedRx and MyStart Health available in my state?

ShedRx is available in all 50 states. MyStart Health is available in all 50 states.

Not sure ShedRx or MyStart Health is right for you?

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