MyStart Health vs Sesame Care: Which GLP-1 Program Is Better? (2026)
A detailed side-by-side comparison of MyStart Health and Sesame Care to help you choose the right GLP-1 weight loss program based on pricing, medications, medical support, and more.
Quick Verdict
We recommend MyStart Health
Between these two providers, MyStart Health is our pick for most users. It offers a higher overall rating (8 vs 7.8). That said, Sesame Care may be the better fit if you are looking for users who want cheap doctor visits and already have insurance to cover brand-name medications.
Side-by-Side Comparison
| Feature | MyStart Health | Sesame Care |
|---|---|---|
| Monthly Price | $179 | $25 |
| Rating | 8 / 10 | 7.8 / 10 |
| Medication Type | Brand & Compounded | Brand & Compounded |
| Insurance Accepted | No | Yes |
| States Available | All 50 states | All 50 states |
| Consultation Fee | Free | $25-75 |
| Shipping | Free Shipping | Paid |
| Cancel Anytime | Yes | Yes |
| Medical Support | Licensed U.S. physicians, unlimited clinician access | Licensed physicians, per-visit model |
Prices reflect starting rates without insurance. Actual costs may vary by plan and medication. Last updated March 2026.
MyStart Health: Detailed Look
MyStart Health
GLP-1 programs with a price-lock guarantee and weight-loss promise
Pros
- Price Lock Guarantee — your rate never increases with dosage
- 10% bodyweight loss in 4 months or money back
- All-inclusive pricing with free shipping and labs
- Available in all 50 states with 24-hour consultation turnaround
Cons
- Some reports of shipping and fulfillment delays
- Tirzepatide option is significantly more expensive at $429/month
Users who value a money-back weight-loss guarantee and price-lock protection
Sesame Care: Detailed Look
Sesame Care
Affordable telehealth marketplace connecting patients with doctors from $25
Pros
- Lowest consultation cost — visits from just $25
- Prescribes brand-name FDA-approved medications
- Transparent per-visit pricing with no subscriptions
- Wide network of licensed physicians across all 50 states
Cons
- Medication cost is separate and not included in visit fee
- No compounded options — brand-name only (higher drug cost)
Users who want cheap doctor visits and already have insurance to cover brand-name medications
Which Should You Choose?
The right choice depends on your specific needs and priorities. Here is a quick decision framework:
Go with Sesame Care at $25/month. $25-75 per visit; medication costs separate.
MyStart Health has the edge with a 8 rating.
Sesame Care accepts insurance, which can significantly reduce your out-of-pocket cost.
Compare their support: MyStart Health offers licensed u.s. physicians, unlimited clinician access, while Sesame Care provides licensed physicians, per-visit model.
MyStart Health at $179/month may offer features that justify the premium.
Frequently Asked Questions
Is MyStart Health better than Sesame Care?
MyStart Health has a 8 rating while Sesame Care has a 7.8 rating. The better choice depends on your priorities — MyStart Health is best for users who value a money-back weight-loss guarantee and price-lock protection, while Sesame Care is best for users who want cheap doctor visits and already have insurance to cover brand-name medications.
How much does MyStart Health cost compared to Sesame Care?
MyStart Health starts at $179/month ($249/mo semaglutide, $429/mo tirzepatide), while Sesame Care starts at $25/month ($25-75 per visit; medication costs separate).
Do MyStart Health and Sesame Care accept insurance?
MyStart Health does not accept insurance. Sesame Care accepts insurance.
Which GLP-1 medications does MyStart Health offer vs Sesame Care?
MyStart Health offers Compounded Semaglutide, Compounded Tirzepatide, Ozempic, Wegovy. Sesame Care offers Ozempic, Wegovy, Mounjaro, Zepbound, Rybelsus.
Can I cancel MyStart Health or Sesame Care at any time?
MyStart Health allows cancel anytime. Sesame Care also allows cancel anytime.
Are MyStart Health and Sesame Care available in my state?
MyStart Health is available in all 50 states. Sesame Care is available in all 50 states.