MyStart Health vs Sesame Care: Which GLP-1 Program Is Better? (2026)

A detailed side-by-side comparison of MyStart Health and Sesame Care to help you choose the right GLP-1 weight loss program based on pricing, medications, medical support, and more.

Eduard Cristea
Eduard Cristea
Dr. A. Goher, MD
Medically reviewed by Dr. A. Goher, MD
Published:

Quick Verdict

We recommend MyStart Health

Between these two providers, MyStart Health is our pick for most users. It offers a higher overall rating (8.5 vs 7.2), more affordable pricing. That said, Sesame Care may be the better fit if you are looking for users with insurance who want cheap doctor visits — medication costs are separate and not included.

MyStart Health scores 8.5/10 in our independent evaluation at $224/month, while Sesame Care scores 7.2/10 at $225/month. Both programs include a licensed physician consultation and ship medication directly to your door. Our rating considers five factors: safety and medical oversight (30%), pricing transparency (25%), cost value (20%), clinical support quality (15%), and onboarding speed (10%). This comparison was independently produced — neither provider pays for placement or higher ratings. Prices verified April 2026.

Side-by-Side Comparison

Monthly Price
MyStart Health
$224
Sesame Care
$225
Rating
MyStart Health
8.5 / 10
Sesame Care
7.2 / 10
Medication Type
MyStart Health
Brand & Compounded
Sesame Care
Brand & Compounded
Insurance Accepted
MyStart Health
No
Sesame Care
Yes
States Available
MyStart Health
All 50 states
Sesame Care
All 50 states
Consultation Fee
MyStart Health
Free
Sesame Care
$25-75
Shipping
MyStart Health
Free Shipping
Sesame Care
Paid
Cancel Anytime
MyStart Health
Yes
Sesame Care
Yes
Medical Support
MyStart Health
Licensed U.S. physicians, unlimited clinician access
Sesame Care
Licensed physicians, per-visit model

Prices reflect starting rates without insurance. Actual costs may vary by plan and medication. Last updated April 2026.

MyStart Health: Detailed Look

MyStart Health

GLP-1 programs with a price-lock guarantee and weight-loss promise

8.5/10
Excellent

Pros

  • Price Lock Guarantee — your rate never increases with dosage
  • 10% bodyweight loss in 4 months or money back
  • All-inclusive pricing with free shipping and labs
  • Available in all 50 states with 24-hour consultation turnaround

Cons

  • Some reports of shipping and fulfillment delays
  • Tirzepatide option is significantly more expensive at $429/month
Best For

Users who value a money-back weight-loss guarantee and price-lock protection

Sesame Care: Detailed Look

Sesame Care

Affordable telehealth marketplace connecting patients with doctors from $25

7.2/10
Good

Pros

  • Lowest consultation cost — visits from just $25
  • Prescribes brand-name FDA-approved medications
  • Transparent per-visit pricing with no subscriptions
  • Wide network of licensed physicians across all 50 states

Cons

  • Medication cost is separate and not included in visit fee
  • No compounded options — brand-name only (higher drug cost)
Best For

Users with insurance who want cheap doctor visits — medication costs are separate and not included

Which Should You Choose?

The right choice depends on your specific needs and priorities. Here is a quick decision framework:

You want the lowest monthly cost

Go with MyStart Health at $224/month. $299/mo (use code SELFLOVE25 for 25% off = $224/mo). Includes meds, labs, shipping, unlimited clinician access.

You want the highest-rated program

MyStart Health has the edge with a 8.5 rating.

You have insurance coverage

Sesame Care accepts insurance, which can significantly reduce your out-of-pocket cost.

You want comprehensive medical support

Compare their support: MyStart Health offers licensed u.s. physicians, unlimited clinician access, while Sesame Care provides licensed physicians, per-visit model.

You are willing to invest more for premium care

Sesame Care at $225/month may offer features that justify the premium.

MyStart Health

Starting at $224/mo · Excellent

Visit MyStart Health

Sesame Care

Starting at $225/mo · Good

Visit Sesame Care

Frequently Asked Questions

Is MyStart Health better than Sesame Care?

MyStart Health has a 8.5 rating while Sesame Care has a 7.2 rating. The better choice depends on your priorities — MyStart Health is best for users who value a money-back weight-loss guarantee and price-lock protection, while Sesame Care is best for users with insurance who want cheap doctor visits — medication costs are separate and not included.

How much does MyStart Health cost compared to Sesame Care?

MyStart Health starts at $224/month ($299/mo (use code selflove25 for 25% off = $224/mo). includes meds, labs, shipping, unlimited clinician access), while Sesame Care starts at $225/month ($25-75 per visit + medication at pharmacy prices ($200-1,400/mo). total starting cost ~$225/mo with insurance savings cards. medication not included in visit fee.).

Do MyStart Health and Sesame Care accept insurance?

MyStart Health does not accept insurance. Sesame Care accepts insurance.

Which GLP-1 medications does MyStart Health offer vs Sesame Care?

MyStart Health offers Compounded Semaglutide, Compounded Tirzepatide, Ozempic, Wegovy. Sesame Care offers Ozempic, Wegovy, Mounjaro, Zepbound, Rybelsus.

Can I cancel MyStart Health or Sesame Care at any time?

MyStart Health allows cancel anytime. Sesame Care also allows cancel anytime.

Are MyStart Health and Sesame Care available in my state?

MyStart Health is available in all 50 states. Sesame Care is available in all 50 states.