Enhance MD vs Zealthy: Which GLP-1 Program Is Better? (2026)

A detailed side-by-side comparison of Enhance MD and Zealthy to help you choose the right GLP-1 weight loss program based on pricing, medications, medical support, and more.

By GLP-1 Watchdog Editorial TeamIndependent Health Research
Published: March 30, 2026|Updated: March 30, 2026

Quick Verdict

We recommend Enhance MD

Between these two providers, Enhance MD is our pick for most users. It offers a higher overall rating (8.3 vs 7.6), more affordable pricing. That said, Zealthy may be the better fit if you are looking for users who want the option to switch between compounded and brand-name glp-1s.

Side-by-Side Comparison

FeatureEnhance MDZealthy
Monthly Price$115$151
Rating8.3 / 107.6 / 10
Medication TypeBrand & CompoundedBrand & Compounded
Insurance AcceptedNoNo
States AvailableAll 50 statesAll 50 states
Consultation FeeIncluded$135/mo membership
ShippingFree ShippingFree Shipping
Cancel AnytimeYesYes
Medical SupportBoard-certified physiciansLicensed physicians, ongoing clinical support

Prices reflect starting rates without insurance. Actual costs may vary by plan and medication. Last updated March 2026.

Enhance MD: Detailed Look

Enhance MD

Physician-led weight management with NAD+ options

8.3/10
Good

Pros

  • Affordable entry point starting at $115/month
  • Unique NAD+ therapy option alongside GLP-1
  • Board-certified physicians lead all protocols

Cons

  • NAD+ weight loss claims lack strong clinical evidence
  • Less transparent about which medications are compounded vs brand
Best For

Budget-conscious users interested in combination therapies

Zealthy: Detailed Look

Zealthy

Physician-supervised GLP-1 with both compounded and brand-name access

7.6/10
Good

Pros

  • Access to both compounded and FDA-approved brand-name medications
  • Bulk 3-month purchasing lowers per-month cost significantly
  • Physician-supervised with ongoing clinical support
  • Can facilitate brand-name prescriptions for insured patients

Cons

  • Separate $135/month membership fee adds to total cost
  • Bundled pricing ($297-449/mo) is higher than many competitors
Best For

Users who want the option to switch between compounded and brand-name GLP-1s

Which Should You Choose?

The right choice depends on your specific needs and priorities. Here is a quick decision framework:

You want the lowest monthly cost

Go with Enhance MD at $115/month. $115 standard; $250 with NAD+ therapy.

You want the highest-rated program

Enhance MD has the edge with a 8.3 rating.

You want comprehensive medical support

Compare their support: Enhance MD offers board-certified physicians, while Zealthy provides licensed physicians, ongoing clinical support.

You are willing to invest more for premium care

Zealthy at $151/month may offer features that justify the premium.

Enhance MD

Starting at $115/mo · Good

Visit Enhance MD

Zealthy

Starting at $151/mo · Good

Visit Zealthy

Frequently Asked Questions

Is Enhance MD better than Zealthy?

Enhance MD has a 8.3 rating while Zealthy has a 7.6 rating. The better choice depends on your priorities — Enhance MD is best for budget-conscious users interested in combination therapies, while Zealthy is best for users who want the option to switch between compounded and brand-name glp-1s.

How much does Enhance MD cost compared to Zealthy?

Enhance MD starts at $115/month ($115 standard; $250 with nad+ therapy), while Zealthy starts at $151/month ($151/mo semaglutide (3-mo bulk); bundled plans $297-449/mo).

Do Enhance MD and Zealthy accept insurance?

Enhance MD does not accept insurance. Zealthy does not accept insurance.

Which GLP-1 medications does Enhance MD offer vs Zealthy?

Enhance MD offers Semaglutide, Tirzepatide, NAD+. Zealthy offers Compounded Semaglutide, Compounded Tirzepatide, Wegovy, Zepbound.

Can I cancel Enhance MD or Zealthy at any time?

Enhance MD allows cancel anytime. Zealthy also allows cancel anytime.

Are Enhance MD and Zealthy available in my state?

Enhance MD is available in all 50 states. Zealthy is available in all 50 states.

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