Enhance MD vs Novi: Which GLP-1 Program Is Better? (2026)
A detailed side-by-side comparison of Enhance MD and Novi to help you choose the right GLP-1 weight loss program based on pricing, medications, medical support, and more.
Quick Verdict
We recommend Enhance MD
Between these two providers, Enhance MD is our pick for most users. It offers a higher overall rating (8.3 vs 7.3), availability in all 50 states. That said, Novi may be the better fit if you are looking for users who want flexible, no-contract glp-1 access with strong clinical support.
Enhance MD scores 8.3/10 in our independent evaluation at $249/month, while Novi scores 7.3/10 at $199/month. Both programs include a licensed physician consultation and ship medication directly to your door. Our rating considers five factors: safety and medical oversight (30%), pricing transparency (25%), cost value (20%), clinical support quality (15%), and onboarding speed (10%). This comparison was independently produced — neither provider pays for placement or higher ratings. Prices verified April 2026.
Side-by-Side Comparison
| Feature | Enhance MD | Novi |
|---|---|---|
| Monthly Price | $249 | $199 |
| Rating | 8.3 / 10 | 7.3 / 10 |
| Medication Type | Brand & Compounded | Brand & Compounded |
| Insurance Accepted | No | No |
| States Available | All 50 states | 45 states |
| Consultation Fee | Included | Included |
| Shipping | Free Shipping | Free Shipping |
| Cancel Anytime | Yes | Yes |
| Medical Support | Board-certified physicians | Licensed physicians, unlimited access, nutritionist meal plans |
Prices reflect starting rates without insurance. Actual costs may vary by plan and medication. Last updated April 2026.
Enhance MD: Detailed Look
Enhance MD
Physician-led weight management with NAD+ options
Pros
- Affordable entry point starting at $115/month
- Unique NAD+ therapy option alongside GLP-1
- Board-certified physicians lead all protocols
Cons
- NAD+ weight loss claims lack strong clinical evidence
- Less transparent about which medications are compounded vs brand
Budget-conscious users interested in combination therapies
Novi: Detailed Look
Novi
No-contract GLP-1 access with unlimited clinician support from $199/mo
Pros
- All-in transparent pricing with no hidden fees
- Unlimited clinician access for check-ins and dose adjustments
- Month-to-month with no contracts or minimum commitments
- Includes nutritionist-crafted meal plans and online community
Cons
- No refunds once a prescription has been shipped
- Relatively new with limited long-term track record
Users who want flexible, no-contract GLP-1 access with strong clinical support
Which Should You Choose?
The right choice depends on your specific needs and priorities. Here is a quick decision framework:
Go with Novi at $199/month. $199/mo first month, no contract.
Enhance MD has the edge with a 8.3 rating.
Compare their support: Enhance MD offers board-certified physicians, while Novi provides licensed physicians, unlimited access, nutritionist meal plans.
Enhance MD at $249/month may offer features that justify the premium.
Frequently Asked Questions
Is Enhance MD better than Novi?
Enhance MD has a 8.3 rating while Novi has a 7.3 rating. The better choice depends on your priorities — Enhance MD is best for budget-conscious users interested in combination therapies, while Novi is best for users who want flexible, no-contract glp-1 access with strong clinical support.
How much does Enhance MD cost compared to Novi?
Enhance MD starts at $249/month (semaglutide $249/mo; tirzepatide $379/mo; annual plans save ~15%), while Novi starts at $199/month ($199/mo first month, no contract).
Do Enhance MD and Novi accept insurance?
Enhance MD does not accept insurance. Novi does not accept insurance.
Which GLP-1 medications does Enhance MD offer vs Novi?
Enhance MD offers Semaglutide, Tirzepatide, NAD+. Novi offers Compounded Semaglutide, Brand-name GLP-1s.
Can I cancel Enhance MD or Novi at any time?
Enhance MD allows cancel anytime. Novi also allows cancel anytime.
Are Enhance MD and Novi available in my state?
Enhance MD is available in all 50 states. Novi is available in 45 states.