Enhance MD vs MyStart Health: Which GLP-1 Program Is Better? (2026)
A detailed side-by-side comparison of Enhance MD and MyStart Health to help you choose the right GLP-1 weight loss program based on pricing, medications, medical support, and more.
Quick Verdict
We recommend Enhance MD
Between these two providers, Enhance MD is our pick for most users. It offers a higher overall rating (8.3 vs 8), more affordable pricing. That said, MyStart Health may be the better fit if you are looking for users who value a money-back weight-loss guarantee and price-lock protection.
Side-by-Side Comparison
| Feature | Enhance MD | MyStart Health |
|---|---|---|
| Monthly Price | $115 | $179 |
| Rating | 8.3 / 10 | 8 / 10 |
| Medication Type | Brand & Compounded | Brand & Compounded |
| Insurance Accepted | No | No |
| States Available | All 50 states | All 50 states |
| Consultation Fee | Included | Free |
| Shipping | Free Shipping | Free Shipping |
| Cancel Anytime | Yes | Yes |
| Medical Support | Board-certified physicians | Licensed U.S. physicians, unlimited clinician access |
Prices reflect starting rates without insurance. Actual costs may vary by plan and medication. Last updated March 2026.
Enhance MD: Detailed Look
Enhance MD
Physician-led weight management with NAD+ options
Pros
- Affordable entry point starting at $115/month
- Unique NAD+ therapy option alongside GLP-1
- Board-certified physicians lead all protocols
Cons
- NAD+ weight loss claims lack strong clinical evidence
- Less transparent about which medications are compounded vs brand
Budget-conscious users interested in combination therapies
MyStart Health: Detailed Look
MyStart Health
GLP-1 programs with a price-lock guarantee and weight-loss promise
Pros
- Price Lock Guarantee — your rate never increases with dosage
- 10% bodyweight loss in 4 months or money back
- All-inclusive pricing with free shipping and labs
- Available in all 50 states with 24-hour consultation turnaround
Cons
- Some reports of shipping and fulfillment delays
- Tirzepatide option is significantly more expensive at $429/month
Users who value a money-back weight-loss guarantee and price-lock protection
Which Should You Choose?
The right choice depends on your specific needs and priorities. Here is a quick decision framework:
Go with Enhance MD at $115/month. $115 standard; $250 with NAD+ therapy.
Enhance MD has the edge with a 8.3 rating.
Compare their support: Enhance MD offers board-certified physicians, while MyStart Health provides licensed u.s. physicians, unlimited clinician access.
MyStart Health at $179/month may offer features that justify the premium.
Frequently Asked Questions
Is Enhance MD better than MyStart Health?
Enhance MD has a 8.3 rating while MyStart Health has a 8 rating. The better choice depends on your priorities — Enhance MD is best for budget-conscious users interested in combination therapies, while MyStart Health is best for users who value a money-back weight-loss guarantee and price-lock protection.
How much does Enhance MD cost compared to MyStart Health?
Enhance MD starts at $115/month ($115 standard; $250 with nad+ therapy), while MyStart Health starts at $179/month ($249/mo semaglutide, $429/mo tirzepatide).
Do Enhance MD and MyStart Health accept insurance?
Enhance MD does not accept insurance. MyStart Health does not accept insurance.
Which GLP-1 medications does Enhance MD offer vs MyStart Health?
Enhance MD offers Semaglutide, Tirzepatide, NAD+. MyStart Health offers Compounded Semaglutide, Compounded Tirzepatide, Ozempic, Wegovy.
Can I cancel Enhance MD or MyStart Health at any time?
Enhance MD allows cancel anytime. MyStart Health also allows cancel anytime.
Are Enhance MD and MyStart Health available in my state?
Enhance MD is available in all 50 states. MyStart Health is available in all 50 states.