Enhance MD vs Hone Health: Which GLP-1 Program Is Better? (2026)
A detailed side-by-side comparison of Enhance MD and Hone Health to help you choose the right GLP-1 weight loss program based on pricing, medications, medical support, and more.
Quick Verdict
We recommend Enhance MD
Between these two providers, Enhance MD is our pick for most users. It offers a higher overall rating (8.3 vs 8.1), more affordable pricing, availability in all 50 states, both brand-name and compounded medication options. That said, Hone Health may be the better fit if you are looking for users who want a full-service health platform covering weight loss plus hormones and labs.
Side-by-Side Comparison
| Feature | Enhance MD | Hone Health |
|---|---|---|
| Monthly Price | $115 | $160 |
| Rating | 8.3 / 10 | 8.1 / 10 |
| Medication Type | Brand & Compounded | Compounded Only |
| Insurance Accepted | No | No |
| States Available | All 50 states | 44 states |
| Consultation Fee | Included | $65 initial lab kit |
| Shipping | Free Shipping | Free Shipping |
| Cancel Anytime | Yes | Yes |
| Medical Support | Board-certified physicians | Licensed physicians, lab testing, ongoing monitoring |
Prices reflect starting rates without insurance. Actual costs may vary by plan and medication. Last updated March 2026.
Enhance MD: Detailed Look
Enhance MD
Physician-led weight management with NAD+ options
Pros
- Affordable entry point starting at $115/month
- Unique NAD+ therapy option alongside GLP-1
- Board-certified physicians lead all protocols
Cons
- NAD+ weight loss claims lack strong clinical evidence
- Less transparent about which medications are compounded vs brand
Budget-conscious users interested in combination therapies
Hone Health: Detailed Look
Hone Health
Full-service telehealth with GLP-1s, hormone therapy, and lab testing
Pros
- Full clinical platform — weight loss, hormones, longevity, and labs
- Advanced lab diagnostics included to guide treatment
- Private telehealth consults with licensed physicians
- Medications shipped directly to your door
Cons
- Requires separate membership fee ($25-149/mo) on top of medication
- Does not offer semaglutide — only liraglutide and tirzepatide
Users who want a full-service health platform covering weight loss plus hormones and labs
Which Should You Choose?
The right choice depends on your specific needs and priorities. Here is a quick decision framework:
Go with Enhance MD at $115/month. $115 standard; $250 with NAD+ therapy.
Enhance MD has the edge with a 8.3 rating.
Hone Health focuses on compounded medications at a lower price point.
Compare their support: Enhance MD offers board-certified physicians, while Hone Health provides licensed physicians, lab testing, ongoing monitoring.
Hone Health at $160/month may offer features that justify the premium.
Frequently Asked Questions
Is Enhance MD better than Hone Health?
Enhance MD has a 8.3 rating while Hone Health has a 8.1 rating. The better choice depends on your priorities — Enhance MD is best for budget-conscious users interested in combination therapies, while Hone Health is best for users who want a full-service health platform covering weight loss plus hormones and labs.
How much does Enhance MD cost compared to Hone Health?
Enhance MD starts at $115/month ($115 standard; $250 with nad+ therapy), while Hone Health starts at $160/month ($160/mo liraglutide, $349-499/mo tirzepatide + membership fee).
Do Enhance MD and Hone Health accept insurance?
Enhance MD does not accept insurance. Hone Health does not accept insurance.
Which GLP-1 medications does Enhance MD offer vs Hone Health?
Enhance MD offers Semaglutide, Tirzepatide, NAD+. Hone Health offers Compounded Liraglutide, Compounded Tirzepatide.
Can I cancel Enhance MD or Hone Health at any time?
Enhance MD allows cancel anytime. Hone Health also allows cancel anytime.
Are Enhance MD and Hone Health available in my state?
Enhance MD is available in all 50 states. Hone Health is available in 44 states.