Enhance MD vs Fridays: Which GLP-1 Program Is Better? (2026)
A detailed side-by-side comparison of Enhance MD and Fridays to help you choose the right GLP-1 weight loss program based on pricing, medications, medical support, and more.
Quick Verdict
We recommend Enhance MD
Between these two providers, Enhance MD is our pick for most users. It offers a higher overall rating (8.3 vs 6.8), availability in all 50 states. That said, Fridays may be the better fit if you are looking for users who want a holistic program with coaching, nutrition support, and flexible pricing.
Enhance MD scores 8.3/10 in our independent evaluation at $249/month, while Fridays scores 6.8/10 at $249/month. Both programs include a licensed physician consultation and ship medication directly to your door. Our rating considers five factors: safety and medical oversight (30%), pricing transparency (25%), cost value (20%), clinical support quality (15%), and onboarding speed (10%). This comparison was independently produced — neither provider pays for placement or higher ratings. Prices verified April 2026.
Side-by-Side Comparison
| Feature | Enhance MD | Fridays |
|---|---|---|
| Monthly Price | $249 | $249 |
| Rating | 8.3 / 10 | 6.8 / 10 |
| Medication Type | Brand & Compounded | Brand & Compounded |
| Insurance Accepted | No | Yes |
| States Available | All 50 states | 49 states |
| Consultation Fee | Included | Included |
| Shipping | Free Shipping | Free Shipping |
| Cancel Anytime | Yes | Yes |
| Medical Support | Board-certified physicians | Licensed providers, health coaching, nutrition support |
Prices reflect starting rates without insurance. Actual costs may vary by plan and medication. Last updated April 2026.
Enhance MD: Detailed Look
Enhance MD
Physician-led weight management with NAD+ options
Pros
- Affordable entry point starting at $115/month
- Unique NAD+ therapy option alongside GLP-1
- Board-certified physicians lead all protocols
Cons
- NAD+ weight loss claims lack strong clinical evidence
- Less transparent about which medications are compounded vs brand
Budget-conscious users interested in combination therapies
Fridays: Detailed Look
Fridays
Holistic GLP-1 weight loss with coaching, nutrition, and clinical support
Pros
- Plans include provider visits, coaching, and nutrition support
- 12-month plan drops price to as low as $150/month
- Accepts insurance for brand-name medications
- HSA/FSA accepted with itemized receipts
Cons
- Not available in Louisiana (49 states only)
- 12-month plan requires upfront payment for best discount
Users who want a holistic program with coaching, nutrition support, and flexible pricing
Which Should You Choose?
The right choice depends on your specific needs and priorities. Here is a quick decision framework:
Go with Enhance MD at $249/month. Semaglutide $249/mo; tirzepatide $379/mo; annual plans save ~15%.
Enhance MD has the edge with a 8.3 rating.
Fridays accepts insurance, which can significantly reduce your out-of-pocket cost.
Compare their support: Enhance MD offers board-certified physicians, while Fridays provides licensed providers, health coaching, nutrition support.
Frequently Asked Questions
Is Enhance MD better than Fridays?
Enhance MD has a 8.3 rating while Fridays has a 6.8 rating. The better choice depends on your priorities — Enhance MD is best for budget-conscious users interested in combination therapies, while Fridays is best for users who want a holistic program with coaching, nutrition support, and flexible pricing.
How much does Enhance MD cost compared to Fridays?
Enhance MD starts at $249/month (semaglutide $249/mo; tirzepatide $379/mo; annual plans save ~15%), while Fridays starts at $249/month (as low as $150/mo on 12-month plan).
Do Enhance MD and Fridays accept insurance?
Enhance MD does not accept insurance. Fridays accepts insurance.
Which GLP-1 medications does Enhance MD offer vs Fridays?
Enhance MD offers Semaglutide, Tirzepatide, NAD+. Fridays offers Compounded Semaglutide, Compounded Tirzepatide, Brand-name GLP-1s (with insurance).
Can I cancel Enhance MD or Fridays at any time?
Enhance MD allows cancel anytime. Fridays also allows cancel anytime.
Are Enhance MD and Fridays available in my state?
Enhance MD is available in all 50 states. Fridays is available in 49 states.