ShedRx vs DudeMeds: Which GLP-1 Program Is Better? (2026)
A detailed side-by-side comparison of ShedRx and DudeMeds to help you choose the right GLP-1 weight loss program based on pricing, medications, medical support, and more.
Quick Verdict
We recommend ShedRx
Between these two providers, ShedRx is our pick for most users. It offers a higher overall rating (8.8 vs 5.7), availability in all 50 states, both brand-name and compounded medication options. That said, DudeMeds may be the better fit if you are looking for men who want glp-1 weight loss from a men's health-focused platform.
ShedRx scores 8.8/10 in our independent evaluation at $159/month, while DudeMeds scores 5.7/10 at $149/month. Both programs include a licensed physician consultation and ship medication directly to your door. ShedRx also offers oral GLP-1 options for patients who prefer pills over injections. Our rating considers five factors: safety and medical oversight (30%), pricing transparency (25%), cost value (20%), clinical support quality (15%), and onboarding speed (10%). We earn affiliate commissions from some providers, disclosed on this page; no provider can pay to fake safety, licensing, or hide the downsides. Prices verified April 2026.
Side-by-Side Comparison
| Feature | ShedRx | DudeMeds |
|---|---|---|
| Monthly Price | $159 | $149 |
| Rating | 8.8 / 10 | 5.7 / 10 |
| Medication Type | Brand & Compounded | Compounded Only |
| Insurance Accepted | No | No |
| States Available | All 50 states | 46 states |
| Consultation Fee | Included | Free |
| Shipping | Free Shipping | Free Shipping |
| Cancel Anytime | No | Yes |
| Medical Support | Licensed physicians, health coaching, supplement guidance | Licensed clinicians, 24/7 patient portal |
Prices reflect starting rates without insurance. Actual costs may vary by plan and medication. Last updated April 2026.
ShedRx: Detailed Look
ShedRx
150K+ members with 5 medication forms — injections, oral drops, lozenges, tablets, and pills
Pros
- Most delivery forms of any provider: injections, oral drops, lozenges, tablets, and pills
- 120-day guarantee: lose 5% (or reach your goal weight) or your money back — first-time GLP-1 users, coaching and check-in conditions apply
- Both compounded and brand-name options (Wegovy, Zepbound)
- 150,000+ members, health coaching and supplements included
Cons
- 2-month minimum on every plan; the $159 rate needs a 12-month commitment ($199 month-to-month)
- Recurring Trustpilot complaints about cancellations, reaching support and unexpected charges
Users who want multiple medication delivery forms and a money-back weight loss guarantee
DudeMeds: Detailed Look
DudeMeds
Men's health platform with GLP-1 weight loss in oral and injectable forms
Pros
- No membership fee, no doctor fee, no hidden fees
- Free shipping with 48-hour turnaround after approval
- 24/7 patient portal with clinician access
- Oral and injectable GLP-1 options available
Cons
- Pricing not transparent upfront — must complete intake to see cost
- Originally a men's TRT clinic — weight loss is a newer offering
Men who want GLP-1 weight loss from a men's health-focused platform
Which Should You Choose?
The right choice depends on your specific needs and priorities. Here is a quick decision framework:
Go with DudeMeds at $149/month. Advertised "Starting at $149/mo" compounded semaglutide and "Starting at $233/mo" compounded tirzepatide, consistent across dudemeds.com's new-patient, clinic-switch and refill shop pages (read 2026-09-01). Those pages carry "Launch Prices / Commit & Save" framing with a countdown that renders as 00:00:00:00, but DudeMeds publishes no separate non-launch price anywhere, so these are the only advertised figures. Per-term commitment tiers sit behind the intake funnel and are not publicly readable..
ShedRx has the edge with a 8.8 rating.
DudeMeds focuses on compounded medications at a lower price point.
Compare their support: ShedRx offers licensed physicians, health coaching, supplement guidance, while DudeMeds provides licensed clinicians, 24/7 patient portal.
ShedRx at $159/month may offer features that justify the premium.
Frequently Asked Questions
Is ShedRx better than DudeMeds?
ShedRx has a 8.8 rating while DudeMeds has a 5.7 rating. The better choice depends on your priorities — ShedRx is best for users who want multiple medication delivery forms and a money-back weight loss guarantee, while DudeMeds is best for men who want glp-1 weight loss from a men's health-focused platform.
How much does ShedRx cost compared to DudeMeds?
ShedRx starts at $159/month (now trading as shed (tryshed.com). compounded semaglutide from $159/mo (12-month plan; $179 6-month, $199 monthly) and tirzepatide from $239/mo ($269 / $299). oral options: lozenges from $199, liquid drops from $229, semaglutide tablets from $299. brand pathway: wegovy pill $149 / pen $199, zepbound $349, foundayo $149 — medication only, plus a $125/mo shed membership. every plan carries a 2-month minimum.), while DudeMeds starts at $149/month (advertised "starting at $149/mo" compounded semaglutide and "starting at $233/mo" compounded tirzepatide, consistent across dudemeds.com's new-patient, clinic-switch and refill shop pages (read 2026-09-01). those pages carry "launch prices / commit & save" framing with a countdown that renders as 00:00:00:00, but dudemeds publishes no separate non-launch price anywhere, so these are the only advertised figures. per-term commitment tiers sit behind the intake funnel and are not publicly readable.).
Do ShedRx and DudeMeds accept insurance?
ShedRx does not accept insurance. DudeMeds does not accept insurance.
Which GLP-1 medications does ShedRx offer vs DudeMeds?
ShedRx offers Compounded Semaglutide, Compounded Tirzepatide, Wegovy, Zepbound, Foundayo (oral orforglipron). DudeMeds offers Compounded Semaglutide (Oral), Compounded Semaglutide (Injectable), Compounded Tirzepatide.
Can I cancel ShedRx or DudeMeds at any time?
ShedRx may have cancellation restrictions. DudeMeds also allows cancel anytime.
Are ShedRx and DudeMeds available in my state?
ShedRx is available in all 50 states. DudeMeds is available in 46 states.
Not sure ShedRx or DudeMeds is right for you?
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